Related papers: Prompt gamma ray diagnostics and enhanced hadron-t…
The accurate imaging and quantitative measurement of 478-keV prompt gamma rays are critical for advancing boron neutron capture therapy (BNCT), a promising cancer treatment. Although numerical simulations have indicated that such…
Background and purpose: Accelerator-Based Boron Neutron Capture Therapy is a radiotherapy based on compact accelerator neutron sources requiring an epithermal neutron field for tumour irradiations. Neutrons of 10 keV are considered as the…
Protontherapy is hadrontherapy fastest-growing modality and a pillar in the battle against cancer. Hadrontherapy superiority lies in its inverted depth-dose profile, hence tumour-confined irradiation. Protons, however, lack distinct…
The proton boron fusion reaction, 11B(p, 3{\alpha}), is investigated using MCNP6 to assess the viability for potential use in radiation therapy. The 11B(p, 3{\alpha}) is theoretically desirable because it could combine the localized dose…
Boron Neutron Capture Therapy (BNCT) is a neutron radiotherapy used to treat tumours cells previously doping with Boron-10. This therapy requires an epithermal neutron beam for the treatment of deep tumours and a thermal beam for shallow…
Boron Neutron Capture Therapy (BNCT) is a form of radiotherapy based on the irradiation of the tumour with a low energy neutron beam, after the administration of a selective drug enriched in boron-10. The therapy exploits the high cross…
Hadron therapy, because of the dosimetric and radiobiological advantages, is more and more often used in tumour treatment. This treatment method leads also to the radioactive effects induced by energetic protons on nuclei. Nuclear reactions…
Boron Neutron Capture Therapy (BNCT), is an advanced cancer therapy that destroys the cancer tumors using the well-known Li(p,n)Be . Because of the highly selectively reaction between a boron and a neutron, BNCT is effective for rapidly…
Dosimetry in BNCT poses significant challenges due to the indirect effect of neutrons interacting with elements within the body and uncertainties associated with the uptake of boron compounds used in clinical practice. Current treatment…
A work recently published experimentally demonstrates an increase in the radiobiological efficacy of clinical proton beams when a tumour is treated in the presence of a concentration of 11B. The paper, for the first time, demonstrates the…
Aneutronic and nonradioactive properties make the proton-boron fusion a prospective candidate for fusion energy production through reactions following p+$^{11}$B$\rightarrow$3${\alpha}$ (p-$^{11}$B). However, it is difficult to achieve a…
Selective accumulation of B-10 compound in tumour tissue is a fundamental condition for the achievement of BNCT (Boron Neutron Capture Therapy), since the effectiveness of therapy irradiation derives just from neutron capture reaction of…
The advent of high-intensity pulsed laser technology enables the generation of extreme states of matter under conditions that are far from thermal equilibrium. This in turn could enable different approaches to generating energy from nuclear…
We investigate the feasibility of using laser accelerated protons/deuterons for positron emission tomography (PET) isotope production by means of the nuclear reactions $^{11}$B($p,n$)$^{11}$C and $^{10}$B($d,n$)$^{11}$C. The second reaction…
To improve the quality of cancer treatment with protons, a translation of X-ray Computed Tomography (CT) images into a map of the proton stopping powers needs to be more accurate. Proton stopping powers determined from CT images have…
Monitoring the dose delivered during proton and carbon ion therapy is still a matter of research. Among the possible solutions, several exploit the measurement of the single photon emission from nuclear decays induced by the irradiation. To…
We present calculations and simulations on the role of the p+$^{11}$B$\to$3$\alpha$ reaction in proton therapy. This reaction has been recently suggested to be responsible for a decrease in the survival probability of tumor cells, when they…
The prompt gamma ray emission was investigated in the 16A MeV energy region by means of the 36,40Ar+96,92Zr fusion reactions leading to a compound nucleus in the vicinity of 132Ce. We show that the prompt radiation, which appears to be…
Radiotherapy is one of the main methods in the successful treatment of cancer. The tumor is irradiated with photons or charged particles (e.g. protons), and in the case of massive charged particles, the treatment results in less unnecessary…
Short-pulse, ultra high-intensity lasers have opened new regimes for studying fusion plasmas and creating novel ultra-short ion beams and neutron sources. Diagnosing the plasma in these experiments is important for optimizing the fusion…