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Hypertext documents, such as web pages and academic papers, are of great importance in delivering information in our daily life. Although being effective on plain documents, conventional text embedding methods suffer from information loss…

Computation and Language · Computer Science 2018-05-11 Jialong Han , Yan Song , Wayne Xin Zhao , Shuming Shi , Haisong Zhang

We propose Lib2Vec, a novel self-supervised framework to efficiently learn meaningful vector representations of library cells, enabling ML models to capture essential cell semantics. The framework comprises three key components: (1) an…

Machine Learning · Computer Science 2025-04-01 Rongjian Liang , Yi-Chen Lu , Wen-Hao Liu , Haoxing Ren

String matching algorithm plays the vital role in the Computational Biology. The functional and structural relationship of the biological sequence is determined by similarities on that sequence. For that, the researcher is supposed to aware…

Data Structures and Algorithms · Computer Science 2014-01-30 Pandiselvam. P , Marimuthu. T , Lawrance. R

With the consolidation of deep learning in drug discovery, several novel algorithms for learning molecular representations have been proposed. Despite the interest of the community in developing new methods for learning molecular embeddings…

Biomolecules · Quantitative Biology 2022-05-09 María Virginia Sabando , Ignacio Ponzoni , Evangelos E. Milios , Axel J. Soto

Unsupervised text embeddings extraction is crucial for text understanding in machine learning. Word2Vec and its variants have received substantial success in mapping words with similar syntactic or semantic meaning to vectors close to each…

Computation and Language · Computer Science 2018-05-30 Furong Huang , Animashree Anandkumar

Learning accurate drug representation is essential for tasks such as computational drug repositioning and prediction of drug side-effects. A drug hierarchy is a valuable source that encodes human knowledge of drug relations in a tree-like…

Machine Learning · Computer Science 2020-06-02 Ke Yu , Shyam Visweswaran , Kayhan Batmanghelich

Machine- and deep-learning approaches for biological sequences depend critically on transforming raw DNA, RNA, and protein FASTA files into informative numerical representations. However, this process is often fragmented across multiple…

Genomics · Quantitative Biology 2025-12-01 Hamid Ismail , Marwan Bikdash

The rapid development of high-throughput sequencing technologies has led to an explosive increase in biological sequence data, making sequence clustering a fundamental task in large-scale bioinformatics analyses. Unlike traditional…

Genomics · Quantitative Biology 2026-01-22 Simeng Zhang , Xinying Liu , Jun Lou , Mudi Jiang , Quan Zou , Zengyou He

Sentence embeddings have become an essential part of today's natural language processing (NLP) systems, especially together advanced deep learning methods. Although pre-trained sentence encoders are available in the general domain, none…

Computation and Language · Computer Science 2020-01-28 Qingyu Chen , Yifan Peng , Zhiyong Lu

While several feature embedding models have been developed in the literature, comparisons of these embeddings have largely focused on their numerical performance in classification-related downstream applications. However, an interpretable…

Machine Learning · Computer Science 2025-08-19 Mohammad Jalali , Bahar Dibaei Nia , Farzan Farnia

We propose a novel method for establishing correspondence between two sequences of 2D images. One particular application of this technique is slice-level content navigation, where the goal is to localize specific 2D slices within a 3D…

Computer Vision and Pattern Recognition · Computer Science 2026-02-16 Dingjie Su , Weixiang Hong , Benoit M. Dawant , Bennett A. Landman

We propose a new kernel for biological sequences which borrows ideas and techniques from information theory and data compression. This kernel can be used in combination with any kernel method, in particular Support Vector Machines for…

Genomics · Quantitative Biology 2011-01-05 Marco Cuturi , Jean-Philippe Vert

Proteins play a pivotal role in biological systems. The use of machine learning algorithms for protein classification can assist and even guide biological experiments, offering crucial insights for biotechnological applications. We…

Quantitative Methods · Quantitative Biology 2024-10-24 Yizheng Wang , Yixiao Zhai , Yijie Ding , Quan Zou

Kernel classifiers and regressors designed for structured data, such as sequences, trees and graphs, have significantly advanced a number of interdisciplinary areas such as computational biology and drug design. Typically, kernels are…

Machine Learning · Computer Science 2020-01-14 Hanjun Dai , Bo Dai , Le Song

To obtain insights from event data, advanced process mining methods assess the similarity of activities to incorporate their semantic relations into the analysis. Here, distributional similarity that captures similarity from activity…

Databases · Computer Science 2025-09-12 Henrik Kirchmann , Stephan A. Fahrenkrog-Petersen , Xixi Lu , Matthias Weidlich

With the rapid development of biomedical software and hardware, a large amount of relational data interlinking genes, proteins, chemical components, drugs, diseases, and symptoms has been collected for modern biomedical research. Many…

Artificial Intelligence · Computer Science 2021-01-21 Yankai Chen , Yaozu Wu , Shicheng Ma , Irwin King

Biomedical association studies are increasingly done using clinical concepts, and in particular diagnostic codes from clinical data repositories as phenotypes. Clinical concepts can be represented in a meaningful, vector space using word…

Quantitative Methods · Quantitative Biology 2018-11-06 Brett K. Beaulieu-Jones , Isaac S. Kohane , Andrew L. Beam

Representation learning is a fundamental building block for analyzing entities in a database. While the existing embedding learning methods are effective in various data mining problems, their applicability is often limited because these…

Machine Learning · Computer Science 2020-09-24 Chin-Chia Michael Yeh , Dhruv Gelda , Zhongfang Zhuang , Yan Zheng , Liang Gou , Wei Zhang

Deep learning, a rebranding of deep neural network research works, has achieved a remarkable success in recent years. With multiple hidden layers, deep learning models aim at computing the hierarchical feature representations of the…

Neural and Evolutionary Computing · Computer Science 2018-06-06 Jiawei Zhang , Limeng Cui , Fisher B. Gouza

Distributional semantics models derive word space from linguistic items in context. Meaning is obtained by defining a distance measure between vectors corresponding to lexical entities. Such vectors present several problems. In this paper…

Computation and Language · Computer Science 2017-12-25 Jakub Dutkiewicz , Czesław Jędrzejek
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