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Sequence classification is the supervised learning task of building models that predict class labels of unseen sequences of symbols. Although accuracy is paramount, in certain scenarios interpretability is a must. Unfortunately, such…

Machine Learning · Computer Science 2020-06-26 Severin Gsponer , Luca Costabello , Chan Le Van , Sumit Pai , Christophe Gueret , Georgiana Ifrim , Freddy Lecue

Protein-ligand interactions are one of the fundamental types of molecular interactions in living systems. Ligands are small molecules that interact with protein molecules at specific regions on their surfaces called binding sites. Tasks…

Biomolecules · Quantitative Biology 2020-08-11 Arnab Bhadra , Kalidas Y

In sequence-based predictions, conventionally an input sequence is represented by a multiple sequence alignment (MSA) or a representation derived from MSA, such as a position-specific scoring matrix. Recently, inspired by the development in…

Quantitative Methods · Quantitative Biology 2021-10-18 Nabil Ibtehaz , Daisuke Kihara

DNA sequence alignment involves assigning short DNA reads to the most probable locations on an extensive reference genome. This process is crucial for various genomic analyses, including variant calling, transcriptomics, and epigenomics.…

In this paper a novel biclustering algorithm based on artificial intelligence (AI) is introduced. The method called EBIC aims to detect biologically meaningful, order-preserving patterns in complex data. The proposed algorithm is probably…

Machine Learning · Computer Science 2018-07-27 Patryk Orzechowski , Moshe Sipper , Xiuzhen Huang , Jason H. Moore

Encoder-decoder recurrent neural network models (RNN Seq2Seq) have achieved great success in ubiquitous areas of computation and applications. It was shown to be successful in modeling data with both temporal and spatial dependencies for…

Machine Learning · Computer Science 2020-02-03 Kun Su , Eli Shlizerman

With the recent success of embeddings in natural language processing, research has been conducted into applying similar methods to code analysis. Most works attempt to process the code directly or use a syntactic tree representation,…

Machine Learning · Computer Science 2018-11-30 Tal Ben-Nun , Alice Shoshana Jakobovits , Torsten Hoefler

Modern single-cell flow and mass cytometry technologies measure the expression of several proteins of the individual cells within a blood or tissue sample. Each profiled biological sample is thus represented by a set of hundreds of…

Machine Learning · Computer Science 2022-06-29 Siyuan Shan , Vishal Baskaran , Haidong Yi , Jolene Ranek , Natalie Stanley , Junier Oliva

Vector-space representations provide geometric tools for reasoning about the similarity of a set of objects and their relationships. Recent machine learning methods for deriving vector-space embeddings of words (e.g., word2vec) have…

Computation and Language · Computer Science 2017-06-12 Dawn Chen , Joshua C. Peterson , Thomas L. Griffiths

In this paper, we present subgraph2vec, a novel approach for learning latent representations of rooted subgraphs from large graphs inspired by recent advancements in Deep Learning and Graph Kernels. These latent representations encode…

Machine Learning · Computer Science 2016-06-30 Annamalai Narayanan , Mahinthan Chandramohan , Lihui Chen , Yang Liu , Santhoshkumar Saminathan

Embeddings mapping high-dimensional discrete input to lower-dimensional continuous vector spaces have been widely adopted in machine learning applications as a way to capture domain semantics. Interviewing 13 embedding users across…

Human-Computer Interaction · Computer Science 2022-03-07 Angie Boggust , Brandon Carter , Arvind Satyanarayan

We argue that time series analysis is fundamentally different in nature to either vision or natural language processing with respect to the forms of meaningful self-supervised learning tasks that can be defined. Motivated by this insight,…

Machine Learning · Computer Science 2023-12-13 Navid Mohammadi Foumani , Chang Wei Tan , Geoffrey I. Webb , Hamid Rezatofighi , Mahsa Salehi

We address the problem of learning a distributed representation of entities in a relational database using a low-dimensional embedding. Low-dimensional embeddings aim to encapsulate a concise vector representation for an underlying dataset…

Databases · Computer Science 2020-05-14 Siddhant Arora , Srikanta Bedathur

High throughput technologies have become the practice of choice for comparative studies in biomedical applications. Limited number of sample points due to sequencing cost or access to organisms of interest necessitates the development of…

Methodology · Statistics 2018-07-17 Ariana Broumand , Siamak Zamani Dadaneh

Node embeddings have been attracting increasing attention during the past years. In this context, we propose a new ensemble node embedding approach, called TenSemble2Vec, by first generating multiple embeddings using the existing techniques…

Machine Learning · Computer Science 2020-08-19 Jia Chen , Evangelos E. Papalexakis

Advances in bioinformatics are primarily due to new algorithms for processing diverse biological data sources. While sophisticated alignment algorithms have been pivotal in analyzing biological sequences, deep learning has substantially…

Gene finding is the task of identifying the locations of coding sequences within the vast amount of genetic code contained in the genome. With an ever increasing quantity of raw genome sequences, gene finding is an important avenue towards…

Genomics · Quantitative Biology 2025-05-07 Frederikke I. Marin , Dennis Pultz , Wouter Boomsma

Vector representation of sentences is important for many text processing tasks that involve clustering, classifying, or ranking sentences. Recently, distributed representation of sentences learned by neural models from unlabeled data has…

Computation and Language · Computer Science 2016-10-27 Tanay Kumar Saha , Shafiq Joty , Naeemul Hassan , Mohammad Al Hasan

In this work, we study whether enforcing strict compositional structure in sequence embeddings yields meaningful geometric organization when applied to protein-protein interaction networks. Using Event2Vec, an additive sequence embedding…

Machine Learning · Computer Science 2026-04-02 Antonin Sulc

Mining tasks over sequential data, such as clickstreams and gene sequences, require a careful design of embeddings usable by learning algorithms. Recent research in feature learning has been extended to sequential data, where each instance…

Machine Learning · Computer Science 2020-07-28 Zhongfang Zhuang , Xiangnan Kong , Elke Rundensteiner , Jihane Zouaoui , Aditya Arora