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In recent years, we have witnessed an increased interest in temporal modeling of patient records from large scale Electronic Health Records (EHR). While simpler RNN models have been used for such problems, memory networks, which in other…

Machine Learning · Computer Science 2020-07-15 Prithwish Chakraborty , Fei Wang , Jianying Hu , Daby Sow

Electronic Medical Records (EMR) are a rich source of patient information, including measurements reflecting physiologic signs and administered therapies. Identifying which variables are useful in predicting clinical outcomes can be…

Machine Learning · Statistics 2019-04-03 Eugene Laksana , Melissa Aczon , Long Ho , Cameron Carlin , David Ledbetter , Randall Wetzel

Electronic health records (EHR) consist of longitudinal clinical observations portrayed with sparsity, irregularity, and high-dimensionality, which become major obstacles in drawing reliable downstream clinical outcomes. Although there…

Machine Learning · Computer Science 2020-11-17 Ahmad Wisnu Mulyadi , Eunji Jun , Heung-Il Suk

Electronic Health Record (EHR) data can be represented as discrete counts over a high dimensional set of possible procedures, diagnoses, and medications. Supervised topic models present an attractive option for incorporating EHR data as…

Machine Learning · Computer Science 2019-11-21 Jason Ren , Russell Kunes , Finale Doshi-Velez

Deep learning has demonstrated success in many applications; however, their use in healthcare has been limited due to the lack of transparency into how they generate predictions. Algorithms such as Recurrent Neural Networks (RNNs) when…

Machine Learning · Computer Science 2021-01-14 Long V. Ho , Melissa D. Aczon , David Ledbetter , Randall Wetzel

We introduce HTAD, a novel model for diagnosis prediction using Electronic Health Records (EHR) represented as Heterogeneous Information Networks. Recent studies on modeling EHR have shown success in automatically learning representations…

Machine Learning · Computer Science 2019-12-24 Anahita Hosseini , Tyler Davis , Majid Sarrafzadeh

The advent of Transformers marked a significant breakthrough in sequence modelling, providing a highly performant architecture capable of leveraging GPU parallelism. However, Transformers are computationally expensive at inference time,…

Machine Learning · Computer Science 2024-05-29 Leo Feng , Frederick Tung , Hossein Hajimirsadeghi , Mohamed Osama Ahmed , Yoshua Bengio , Greg Mori

In high stakes applications such as healthcare and finance analytics, the interpretability of predictive models is required and necessary for domain practitioners to trust the predictions. Traditional machine learning models, e.g., logistic…

Signal Processing · Electrical Eng. & Systems 2020-03-27 Kaiping Zheng , Shaofeng Cai , Horng Ruey Chua , Wei Wang , Kee Yuan Ngiam , Beng Chin Ooi

With the increasing availability of patient data, modern medicine is shifting towards prospective healthcare. Electronic health records offer a variety of information useful for clinical patient characterization and the development of…

Machine Learning · Computer Science 2025-05-27 Fabio Azzalini , Tommaso Dolci , Marco Vagaggini

Extracting actionable insight from Electronic Health Records (EHRs) poses several challenges for traditional machine learning approaches. Patients are often missing data relative to each other; the data comes in a variety of modalities,…

Machine Learning · Computer Science 2018-11-13 Brandon Malone , Alberto Garcia-Duran , Mathias Niepert

Clinical notes contain a large amount of clinically valuable information that is ignored in many clinical decision support systems due to the difficulty that comes with mining that information. Recent work has found success leveraging deep…

Machine Learning · Computer Science 2019-11-13 Justin R. Lovelace , Nathan C. Hurley , Adrian D. Haimovich , Bobak J. Mortazavi

Electronic health records (EHR) is an inherently multimodal register of the patient's health status characterized by static data and multivariate time series (MTS). While MTS are a valuable tool for clinical prediction, their fusion with…

Retentive Network (RetNet) represents a significant advancement in neural network architecture, offering an efficient alternative to the Transformer. While Transformers rely on self-attention to model dependencies, they suffer from high…

Computation and Language · Computer Science 2025-06-10 Haiqi Yang , Zhiyuan Li , Yi Chang , Yuan Wu

Deep neural networks have shown promising results for various clinical prediction tasks such as diagnosis, mortality prediction, predicting duration of stay in hospital, etc. However, training deep networks -- such as those based on…

Machine Learning · Computer Science 2018-07-06 Priyanka Gupta , Pankaj Malhotra , Lovekesh Vig , Gautam Shroff

Predictive modeling with electronic health record (EHR) data is anticipated to drive personalized medicine and improve healthcare quality. Constructing predictive statistical models typically requires extraction of curated predictor…

Electronic health record (EHR) data has emerged as a valuable resource for analyzing patient health status. However, the prevalence of missing data in EHR poses significant challenges to existing methods, leading to spurious correlations…

Machine Learning · Computer Science 2024-05-16 Zhihao Yu , Xu Chu , Yujie Jin , Yasha Wang , Junfeng Zhao

Machine learning (ML) has recently shown promising results in medical predictions using electronic health records (EHRs). However, since ML models typically have a limited capability in terms of input sizes, selecting specific medical…

Machine Learning · Computer Science 2024-07-23 Junu Kim , Chaeeun Shim , Bosco Seong Kyu Yang , Chami Im , Sung Yoon Lim , Han-Gil Jeong , Edward Choi

In longitudinal electronic health records (EHRs), the event records of a patient are distributed over a long period of time and the temporal relations between the events reflect sufficient domain knowledge to benefit prediction tasks such…

Computation and Language · Computer Science 2020-06-16 Xueping Peng , Guodong Long , Tao Shen , Sen Wang , Jing Jiang , Michael Blumenstein

Accurate prediction of medical conditions with straight past clinical evidence is a long-sought topic in the medical management and health insurance field. Although great progress has been made with machine learning algorithms, the medical…

Machine Learning · Computer Science 2024-12-06 Dongping Fang , Lian Duan , Xiaojing Yuan , Allyn Klunder , Kevin Tan , Suiting Cao , Yeqing Ji , Mike Xu

Evaluating the clinical similarities between pairwise patients is a fundamental problem in healthcare informatics. A proper patient similarity measure enables various downstream applications, such as cohort study and treatment comparative…

Machine Learning · Statistics 2019-02-12 Zihao Zhu , Changchang Yin , Buyue Qian , Yu Cheng , Jishang Wei , Fei Wang