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Neural networks are composed of neurons and synapses, which are responsible for learning in a slow adaptive dynamical process. Here we experimentally show that neurons act like independent anisotropic multiplex hubs, which relay and mute…

Neurons and Cognition · Quantitative Biology 2017-07-21 Roni Vardi , Amir Goldental , Anton Sheinin , Shira Sardi , Ido Kanter

We consider the problem of communication over a network containing a hidden and malicious adversary that can control a subset of network resources, and aims to disrupt communications. We focus on omniscient node-based adversaries, i.e., the…

Information Theory · Computer Science 2016-05-09 Peida Tian , Sidharth Jaggi , Mayank Bakshi , Oliver Kosut

Human brain contains about 10 billion neurons, each of which has about 10~10,000 nerve endings from which neurotransmitters are released in response to incoming spikes, and the released neurotransmitters then bind to receptors located in…

Neurons and Cognition · Quantitative Biology 2012-03-06 Xuejuan Zhang , Jianfeng Feng

We quantify the influence of the topology of a transcriptional regulatory network on its ability to process environmental signals. By posing the problem in terms of information theory, we may do this without specifying the function…

Molecular Networks · Quantitative Biology 2015-06-26 Etay Ziv , Ilya Nemenman , Chris H. Wiggins

The human brain prioritises relevant sensory information to perform different tasks. Enhancement of task-relevant information requires flexible allocation of attentional resources, but it is still a mystery how this is operationalised in…

Neurons and Cognition · Quantitative Biology 2021-02-22 Tijl Grootswagers , Amanda K. Robinson , Sophia M. Shatek , Thomas A. Carlson

Recent experiments suggest that inhibitory networks of interneurons can synchronize the neuronal discharge in in vitro hippocampal slices. Subsequent theoretical work has shown that strong synchronization by mutual inhibition is only…

Statistical Mechanics · Physics 2007-05-23 P. H. E Tiesinga , Jorge V Jose

We use a biophysical model of a local neuronal circuit to study the implications of synaptic plasticity for the detection of weak sensory stimuli. Networks with fast plastic coupling show behavior consistent with stochastic resonance.…

Neurons and Cognition · Quantitative Biology 2009-11-13 Vladislav Volman , Herbert Levine

Information transmission in biological signaling circuits has often been described using the metaphor of a noise filter. Cellular systems need accurate, real-time data about their environmental conditions, but the biochemical reaction…

Molecular Networks · Quantitative Biology 2019-02-27 David Hathcock , James Sheehy , Casey Weisenberger , Efe Ilker , Michael Hinczewski

Populations of cells regulate gene expression in response to external signals, but their ability to make reliable collective decisions is limited by both intrinsic noise in molecular signaling and variability between individual cells. In…

Biological Physics · Physics 2026-03-20 Olivier Witteveen , Samuel J. Rosen , Ryan S. Lach , Maxwell Z. Wilson , Marianne Bauer

We would like to know whether the statistics of neuronal responses vary across cortical areas. We examined stimulus-elicited spike count response distributions in V1 and IT cortices of awake monkeys. In both areas the distribution of spike…

Neurons and Cognition · Quantitative Biology 2007-05-23 Ethan D. Gershon , Matthew C. Wiener , Peter E. Latham , Barry J. Richmond

Complex systems are characterized by multiple spatial and temporal scales. A natural framework to capture their multiscale nature is that of multilayer networks, where different layers represent distinct physical processes that often…

Statistical Mechanics · Physics 2024-04-29 Giorgio Nicoletti , Daniel Maria Busiello

Neural activity in the brain exhibits correlated fluctuations that may strongly influence the properties of neural population coding. However, how such correlated neural fluctuations may arise from the intrinsic neural circuit dynamics and…

Biological Physics · Physics 2023-10-18 Hengyuan Ma , Yang Qi , Pulin Gong , Jie Zhang , Wenlian Lu , Jianfeng Feng

Synapses are information efficient in the sense that their natural conductance values convey as many bits per Joule as possible, but efficiency falls rapidly if the conductance is forced to deviate from its natural value (Harris et al,…

Neurons and Cognition · Quantitative Biology 2026-05-19 James V Stone

Neurons in the brain continuously process the barrage of sensory inputs they receive from the environment. A wide array of experimental work has shown that the collective activity of neural populations encodes and processes this constant…

Neurons and Cognition · Quantitative Biology 2025-10-30 Siddharth Paliwal , Gabriel Koch Ocker , Braden A. W. Brinkman

Fluctuations in intracellular reactions (intrinsic noise) reduce the information transmitted from an extracellular input to a cellular response. However, recent studies have demonstrated that the decrease in the transmitted information with…

Molecular Networks · Quantitative Biology 2019-10-09 Takehiro Tottori , Masashi Fujii , Shinya Kuroda

The response of a neural cell to an external stimulus can follow one of the two patterns: Nonresonant neurons monotonously relax to the resting state after excitation while resonant ones show subthreshold oscillations. We investigate how do…

Neurons and Cognition · Quantitative Biology 2009-11-10 T. Verechtchaguina , L. Schimansky-Geier , I. M. Sokolov

In this work we study the detection of weak stimuli by spiking neurons in the presence of certain level of noisy background neural activity. Our study has focused in the realistic assumption that the synapses in the network present…

Neurons and Cognition · Quantitative Biology 2009-06-04 Jorge F. Mejias , Joaquin J. Torres

In this paper, we systematically investigate both the synfire propagation and firing rate propagation in feedforward neuronal network coupled in an all-to-all fashion. In contrast to most earlier work, where only reliable synaptic…

Neurons and Cognition · Quantitative Biology 2015-03-19 Daqing Guo , Chunguang Li

Adversarial examples are often cited by neuroscientists and machine learning researchers as an example of how computational models diverge from biological sensory systems. Recent work has proposed adding biologically-inspired components to…

Neurons and Cognition · Quantitative Biology 2021-11-16 Joel Dapello , Jenelle Feather , Hang Le , Tiago Marques , David D. Cox , Josh H. McDermott , James J. DiCarlo , SueYeon Chung

The magnitude of correlations between stimulus-driven responses of pairs of neurons can itself be stimulus-dependent. We examine how this dependence impacts the information carried by neural populations about the stimuli that drive them.…

Neurons and Cognition · Quantitative Biology 2008-10-14 Kresimir Josic , Eric Shea-Brown , Brent Doiron , Jaime de la Rocha
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