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The evolution of the genome has led to very sophisticated and complex regulation. Because of the abundance of non-coding RNA (ncRNA) in the cell, different species will promiscuously associate with each other, suggesting collective dynamics…

Molecular Networks · Quantitative Biology 2018-05-16 J. M. Deutsch

We study genetic networks that produce many species of non-coding RNA molecules that are present at a moderate density, as typically exists in the cell. The associations of the many species of these RNA are modeled physically, taking into…

Genomics · Quantitative Biology 2014-09-08 J. M. Deutsch

Biology stores information and computes at the molecular scale, yet the ways in which it does so are often distinct from human-engineered computers. Mapping biological computation onto architectures familiar to computer science remains an…

Biological Physics · Physics 2026-03-31 Jan Kocka , Kabir Husain , Jaime Agudo-Canalejo

This paper presents the design of an associative memory with feedback that is capable of on-line temporal sequence learning. A framework for on-line sequence learning has been proposed, and different sequence learning models have been…

Neural and Evolutionary Computing · Computer Science 2007-05-23 J. Bose , S. B. Furber , J. L. Shapiro

We show that macro-molecular self-assembly can recognize and classify high-dimensional patterns in the concentrations of $N$ distinct molecular species. Similar to associative neural networks, the recognition here leverages dynamical…

Disordered Systems and Neural Networks · Physics 2017-04-26 Weishun Zhong , David J. Schwab , Arvind Murugan

The task of a neural associative memory is to retrieve a set of previously memorized patterns from their noisy versions using a network of neurons. An ideal network should have the ability to 1) learn a set of patterns as they arrive, 2)…

Neural and Evolutionary Computing · Computer Science 2014-07-25 Amin Karbasi , Amir Hesam Salavati , Amin Shokrollahi

Associative memories are data structures that allow retrieval of stored messages from part of their content. They thus behave similarly to human brain that is capable for instance of retrieving the end of a song given its beginning. Among…

Neural and Evolutionary Computing · Computer Science 2013-07-25 Bartosz Boguslawski , Vincent Gripon , Fabrice Seguin , Frédéric Heitzmann

Many important phenomena in biochemistry and biology exploit dynamical features such as multi-stability, oscillations, and chaos. Construction of novel chemical systems with such rich dynamics is a challenging problem central to the fields…

Molecular Networks · Quantitative Biology 2026-05-04 Alexander Dack , Benjamin Qureshi , Thomas E. Ouldridge , Tomislav Plesa

Molecular circuits capable of autonomous learning could unlock novel applications in fields such as bioengineering and synthetic biology. To this end, existing chemical implementations of neural computing have mainly relied on emulating…

Machine Learning · Computer Science 2025-09-23 Rajiv Teja Nagipogu , John H. Reif

The brain must robustly store a large number of memories, corresponding to the many events encountered over a lifetime. However, the number of memory states in existing neural network models either grows weakly with network size or recall…

Neurons and Cognition · Quantitative Biology 2017-11-06 Rishidev Chaudhuri , Ila Fiete

Natural memories are associative, declarative and distributed. Symbolic computing memories resemble natural memories in their declarative character, and information can be stored and recovered explicitly; however, they lack the associative…

Artificial Intelligence · Computer Science 2020-09-29 Luis A. Pineda , Gibrán Fuentes , Rafael Morales

Neural associative memories are single layer perceptrons with fast synaptic learning typically storing discrete associations between pairs of neural activity patterns. Previous works have analyzed the optimal networks under naive Bayes…

Neural and Evolutionary Computing · Computer Science 2024-12-25 Andreas Knoblauch

We propose a novel architecture to design a neural associative memory that is capable of learning a large number of patterns and recalling them later in presence of noise. It is based on dividing the neurons into local clusters and parallel…

Neural and Evolutionary Computing · Computer Science 2013-08-26 Amin Karbasi , Amir Hesam Salavati , Amin Shokrollahi

Exactly solvable neural network models with asymmetric weights are rare, and exact solutions are available only in some mean-field approaches. In this article we find exact analytical solutions of an asymmetric spin-glass-like model of…

Neurons and Cognition · Quantitative Biology 2017-02-16 Diego Fasoli , Anna Cattani , Stefano Panzeri

Identifying computational mechanisms for memorization and retrieval of data is a long-standing problem at the intersection of machine learning and neuroscience. Our main finding is that standard overparameterized deep neural networks…

Machine Learning · Computer Science 2022-05-25 Adityanarayanan Radhakrishnan , Mikhail Belkin , Caroline Uhler

Continuous-Time Recurrent Neural Networks (CTRNNs) have been widely used for their capacity to model complex temporal behaviour. However, their internal dynamics often remain difficult to interpret. In this paper, we propose a new class of…

Disordered Systems and Neural Networks · Physics 2025-11-17 Miguel Aguilera , Daniele De Martino , Ivan Garashchuk , Dmitry Sinelshchikov

Humans excel at continually acquiring, consolidating, and retaining information from an ever-changing environment, whereas artificial neural networks (ANNs) exhibit catastrophic forgetting. There are considerable differences in the…

Neural and Evolutionary Computing · Computer Science 2023-04-17 Fahad Sarfraz , Elahe Arani , Bahram Zonooz

Neuron models of associative memory provide a new and prospective technology for reliable date storage and patterns recognition. However, even when the patterns are uncorrelated, the efficiency of most known models of associative memory is…

Disordered Systems and Neural Networks · Physics 2007-05-23 B. V. Kryzhanovsky , L. B. Litinskii , A. Fonarev

Neural Cellular Automata (NCA) represent a powerful framework for modeling biological self-organization, extending classical rule-based systems with trainable, differentiable (or evolvable) update rules that capture the adaptive…

Artificial Intelligence · Computer Science 2025-09-16 Benedikt Hartl , Michael Levin , Léo Pio-Lopez

A method based on mapping a symbolic sequence into a set of patterns (strings resulting from the sequence parsing) is proposed as a tool for the reconstruction of ancestral sequences. The set union of patterns comprises all the patterns…

Genomics · Quantitative Biology 2015-04-16 Bohdan Kozarzewski
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