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We present a novel topological framework for analyzing functional brain signals using time-frequency analysis. By integrating persistent homology with time-frequency representations, we capture multi-scale topological features that…

Neurons and Cognition · Quantitative Biology 2025-04-23 Moo K. Chung , Aaron F. Struck

In recent years, there is a growing need for processing methods aimed at extracting useful information from large datasets. In many cases the challenge is to discover a low-dimensional structure in the data, often concealed by the existence…

Statistics Theory · Mathematics 2019-06-05 Yariv Aizenbud , Boris Landa , Yoel Shkolnisky

The amount of high-dimensional large-scale RNA sequencing data derived from multiple heterogeneous sources has increased exponentially in biological science. During data collection, significant technical noise or errors may occur. To…

Applications · Statistics 2025-06-24 Xiaolu Jiang , Wei Liu

We present a deep semi-nonnegative matrix factorization method for identifying subject-specific functional networks (FNs) at multiple spatial scales with a hierarchical organization from resting state fMRI data. Our method is built upon a…

Computer Vision and Pattern Recognition · Computer Science 2018-09-18 Hongming Li , Xiaofeng Zhu , Yong Fan

Factor analysis provides a canonical framework for imposing lower-dimensional structure such as sparse covariance in high-dimensional data. High-dimensional data on the same set of variables are often collected under different conditions,…

Methodology · Statistics 2024-08-27 Noirrit Kiran Chandra , David B. Dunson , Jason Xu

Magnetic Resonance Imaging (MRI) requires a trade-off between resolution, signal-to-noise ratio, and scan time, making high-resolution (HR) acquisition challenging. Therefore, super-resolution for MR image is a feasible solution. However,…

Image and Video Processing · Electrical Eng. & Systems 2024-09-17 Weifeng Wei , Heng Chen , Pengxiang Su

Factor models are a very efficient way to describe high dimensional vectors of data in terms of a small number of common relevant factors. This problem, which is of fundamental importance in many disciplines, is usually reformulated in…

Optimization and Control · Mathematics 2018-06-13 Valentina Ciccone , Augusto Ferrante , Mattia Zorzi

Multiresolution analysis and matrix factorization are foundational tools in computer vision. In this work, we study the interface between these two distinct topics and obtain techniques to uncover hierarchical block structure in symmetric…

Computer Vision and Pattern Recognition · Computer Science 2017-05-17 Vamsi K. Ithapu , Risi Kondor , Sterling C. Johnson , Vikas Singh

Human brains exhibit highly organized multiscale neurophysiological dynamics. Understanding those dynamic changes and the neuronal networks involved is critical for understanding how the brain functions in health and disease. Functional…

Neurons and Cognition · Quantitative Biology 2024-09-09 Manuel Morante , Kristian Frølich , Naveed ur Rehman

Modern recording techniques enable neuroscientists to simultaneously study neural activity across large populations of neurons, with capturing predictor-dependent correlations being a fundamental challenge in neuroscience. Moreover, the…

Applications · Statistics 2025-02-04 Ganchao Wei

Researchers often have datasets measuring features $x_{ij}$ of samples, such as test scores of students. In factor analysis and PCA, these features are thought to be influenced by unobserved factors, such as skills. Can we determine how…

Statistics Theory · Mathematics 2019-09-16 Edgar Dobriban

In this paper, we set up the theoretical foundations for a high-dimensional functional factor model approach in the analysis of large cross-sections (panels) of functional time series (FTS). We first establish a representation result…

Statistics Theory · Mathematics 2021-04-14 Shahin Tavakoli , Gilles Nisol , Marc Hallin

The connectome, a map of the structural and/or functional connections in the brain, provides a complex representation of the neurobiological phenotypes on which it supervenes. This information-rich data modality has the potential to…

Large-scale association analysis between multivariate responses and predictors is of great practical importance, as exemplified by modern business applications including social media marketing and crisis management. Despite the rapid…

Methodology · Statistics 2020-11-18 Zemin Zheng , Yang Li , Jie Wu , Yuchen Wang

Factor analysis has proven to be a relevant tool for extracting tissue time-activity curves (TACs) in dynamic PET images, since it allows for an unsupervised analysis of the data. Reliable and interpretable results are possible only if…

Image and Video Processing · Electrical Eng. & Systems 2019-03-27 Yanna Cruz Cavalcanti , Thomas Oberlin , Nicolas Dobigeon , Cédric Févotte , Simon Stute , Maria-Joao Ribeiro , Clovis Tauber

Many tasks in data mining and related fields can be formalized as matching between objects in two heterogeneous domains, including collaborative filtering, link prediction, image tagging, and web search. Machine learning techniques,…

Machine Learning · Computer Science 2014-10-24 Jingbo Shang , Tianqi Chen , Hang Li , Zhengdong Lu , Yong Yu

We tackle the challenges of modeling high-dimensional data sets, particularly those with latent low-dimensional structures hidden within complex, non-linear, and noisy relationships. Our approach enables a seamless integration of concepts…

Machine Learning · Statistics 2025-03-17 Zichuan Guo , Mihai Cucuringu , Alexander Y. Shestopaloff

Factors models are routinely used to analyze high-dimensional data in both single-study and multi-study settings. Bayesian inference for such models relies on Markov Chain Monte Carlo (MCMC) methods which scale poorly as the number of…

Methodology · Statistics 2025-04-29 Blake Hansen , Alejandra Avalos-Pacheco , Massimiliano Russo , Roberta De Vito

This paper proposes a hierarchical approximate-factor approach to analyzing high-dimensional, large-scale heterogeneous time series data using distributed computing. The new method employs a multiple-fold dimension reduction procedure using…

Methodology · Statistics 2022-04-20 Zhaoxing Gao , Ruey S. Tsay

This paper proposes the design and implementation strategy of a novel computing architecture, the Factor Machine. The work is a step towards a general-purpose parallel system operating in a non-sequential manner, exploiting…

Hardware Architecture · Computer Science 2024-02-21 Piotr Dudek