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Network flow is a powerful mathematical framework to systematically explore the relationship between structure and function in biological, social, and technological networks. We introduce a new pipelining model of flow through networks…

Neural and Evolutionary Computing · Computer Science 2019-11-04 Lavanya Marla , Lav R. Varshney , Devavrat Shah , Nirmal A. Prakash , Michael E. Gale

Mesh-like structures, such as mucus gel or cytoskeleton networks, are ubiquitous in biological systems. These intricate structures are composed of cross-linked, semi-flexible bio-filaments, crucial to numerous biological processes. In many…

Soft Condensed Matter · Physics 2024-01-10 Yeongjin Kim , Won Kyu Kim , Jae-Hyung Jeon

The metabolic networks are very well characterized for a large set of organisms, a unique case in within the large-scale biological networks. For this reason they provide a a very interesting framework for the construction of analytically…

Molecular Networks · Quantitative Biology 2007-05-23 Ginestra Bianconi , Riccardo Zecchina

As two main focuses of the study of complex networks, the community structure and the dynamics on networks have both attracted much attention in various scientific fields. However, it is still an open question how the community structure is…

Physics and Society · Physics 2010-05-11 Xue-Qi Cheng , Hua-Wei Shen

A major achievement in the study of complex networks is the observation that diverse systems, from sub-cellular biology to social networks, exhibit universal topological characteristics. Yet this universality does not naturally translate to…

Physics and Society · Physics 2018-01-29 Chittaranjan Hens , Uzi Harush , Reuven Cohen , Baruch Barzel

Time plays an essential role in the diffusion of information, influence and disease over networks. In many cases we only observe when a node copies information, makes a decision or becomes infected -- but the connectivity, transmission…

Social and Information Networks · Computer Science 2011-05-05 Manuel Gomez Rodriguez , David Balduzzi , Bernhard Schölkopf

Networks of elastic fibers are ubiquitous in biological systems and often provide mechanical stability to cells and tissues. Fiber reinforced materials are also common in technology. An important characteristic of such materials is their…

Bacterial cellulose biofilms are complex networks of strong interwoven nanofibers that control transport and protect bacterial colonies in the film. Design of diverse applications of bacterial cellulose films also relies on understanding…

Soft Condensed Matter · Physics 2022-06-09 Firoozeh Babayekhorasani , Maryam Hosseini , Patrick T. Spicer

Transportation and distribution networks are a class of spatial networks that have been of interest in recent years. These networks are often characterized by the presence of complex structures such as central loops paired with peripheral…

Physics and Society · Physics 2023-01-23 Sebastiano Bontorin , Giulia Cencetti , Riccardo Gallotti , Bruno Lepri , Manlio De Domenico

Many cellular processes are tightly connected to the dynamics of microtubules (MTs). While in neuronal axons MTs mainly regulate intracellular trafficking, they participate in cytoskeleton reorganization in many other eukaryotic cells,…

Subcellular Processes · Quantitative Biology 2017-12-19 M. Reza Shaebani , Aravind Pasula , Albrecht Ott , Ludger Santen

In this paper we present a network model to study the impact of spatial distribution of constituents, coupling between them and diffusive processes in the context of biological situations. The model is in terms of network of mobile elements…

Molecular Networks · Quantitative Biology 2007-05-23 Kanchan Thadani , Ashutosh

Intracellular dynamics in living tissue are dominated by active transport driven by bioenergetic processes far from thermal equilibrium. Intracellular constituents typically execute persistent walks. In the limit of long mean-free paths,…

Quantitative Methods · Quantitative Biology 2019-04-12 Zhe Li , Hao Sun , John Turek , Shadia Jalal , Michael Childress , David D. Nolte

The rapid diffusion of information and the adoption of social behaviors are of critical importance in situations as diverse as collective actions, pandemic prevention, or advertising and marketing. Although the dynamics of large cascades…

Physics and Society · Physics 2020-12-30 Hao Peng , Azadeh Nematzadeh , Daniel M. Romero , Emilio Ferrara

One of the aims of systems biology is to build multiple layered and multiple scale models of living systems which can efficiently describe phenomena occurring at various level of resolution. Such models should consist of layers of various…

Dynamical Systems · Mathematics 2015-03-03 Jacek Banasiak , Aleksandra Falkiewicz , Proscovia Namayanja

It is known from the wave-like motion of microtubules in motility assays that the piconewton forces that motors produce can be sufficient to bend the filaments. In cellular phenomena such as cytosplasmic streaming, molecular motors…

Soft Condensed Matter · Physics 2017-07-11 Gabriele De Canio , Eric Lauga , Raymond E. Goldstein

The rigidity of elastic networks depends sensitively on their internal connectivity and the nature of the interactions between constituents. Particles interacting via central forces undergo a zero-temperature rigidity-percolation transition…

Soft Condensed Matter · Physics 2011-12-08 Chase P. Broedersz , Xiaoming Mao , T. C. Lubensky , F. C. MacKintosh

Recent experiments reveal both passive subdiffusion of various nanoparticles and anomalous active transport of such particles by molecular motors in the molecularly crowded environment of living biological cells. Passive and active…

Biological Physics · Physics 2014-03-24 Igor Goychuk , Vasyl O. Kharchenko , R. Metzler

Keratin are among the most abundant proteins in epithelial cells. Functions of the keratin network in cells are shaped by their dynamical organization. Using a collection of experimentally-driven mathematical models, different hypotheses…

Subcellular Processes · Quantitative Biology 2015-08-19 Stephanie Portet , Anotida Madzvamuse , Andy Chung , Rudolf E. Leube , Reinhard Windoffer

Numerous networks, such as transportation, distribution and delivery networks optimize their designs in order to increase efficiency and lower costs, improving the stability of its intended functions, etc. Networks that distribute goods,…

Physics and Society · Physics 2020-03-26 Fabricio L. Forgerini , Orahcio F. de Sousa

Active fluid transport is a hallmark of many biological transport networks. While animal circulatory systems generally rely on a single heart to drive flows, other organisms employ decentralized local pumps to distribute fluids and…

Biological Physics · Physics 2024-01-04 Adam B. Dionne , Katharine E. Jensen , Henrik Ronellenfitsch
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