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Deformable image registration (DIR) remains a fundamental yet challenging problem in medical image analysis, largely due to the prohibitively high-dimensional deformation space of dense displacement fields and the scarcity of voxel-level…

Computer Vision and Pattern Recognition · Computer Science 2026-05-19 Runxun Zhang , Yizhou Liu , Li Dongrui , Bo XU , Jingwei Wei

Current trends in scientific imaging are challenged by the emerging need of integrating sophisticated machine learning with Big Data analytics platforms. This work proposes an in-memory distributed learning architecture for enabling…

Distributed, Parallel, and Cluster Computing · Computer Science 2018-10-01 A. Panousopoulou , S. Farrens , K. Fotiadou , A. Woiselle , G. Tsagkatakis , J-L. Starck , P. Tsakalides

Recent works in medical image registration have proposed the use of Implicit Neural Representations, demonstrating performance that rivals state-of-the-art learning-based methods. However, these implicit representations need to be optimized…

Image and Video Processing · Electrical Eng. & Systems 2023-10-04 Louis D. van Harten , Jaap Stoker , Ivana Išgum

Pathologists need to combine information from differently stained pathology slices for accurate diagnosis. Deformable image registration is a necessary technique for fusing multi-modal pathology slices. This paper proposes a hybrid deep…

Image and Video Processing · Electrical Eng. & Systems 2024-10-28 Chulong Zhang , Yuming Jiang , Na Li , Zhicheng Zhang , Md Tauhidul Islam , Jingjing Dai , Lin Liu , Wenfeng He , Wenjian Qin , Jing Xiong , Yaoqin Xie , Xiaokun Liang

Deformable image registration is a fundamental problem in the field of medical image analysis. During the last years, we have witnessed the advent of deep learning-based image registration methods which achieve state-of-the-art performance,…

Image and Video Processing · Electrical Eng. & Systems 2020-02-03 Lucas Mansilla , Diego H. Milone , Enzo Ferrante

We propose a fully unsupervised multi-modal deformable image registration method (UMDIR), which does not require any ground truth deformation fields or any aligned multi-modal image pairs during training. Multi-modal registration is a key…

Computer Vision and Pattern Recognition · Computer Science 2019-03-25 Chen Qin , Bibo Shi , Rui Liao , Tommaso Mansi , Daniel Rueckert , Ali Kamen

We present VoxelMorph, a fast learning-based framework for deformable, pairwise medical image registration. Traditional registration methods optimize an objective function for each pair of images, which can be time-consuming for large…

Computer Vision and Pattern Recognition · Computer Science 2019-09-04 Guha Balakrishnan , Amy Zhao , Mert R. Sabuncu , John Guttag , Adrian V. Dalca

Image deblurring is an economic way to reduce certain degradations (blur and noise) in acquired images. Thus, it has become essential tool in high resolution imaging in many applications, e.g., astronomy, microscopy or computational…

Optimization and Control · Mathematics 2017-05-19 Rahul Mourya , André Ferrari , Rémi Flamary , Pascal Bianchi , Cédric Richard

In this paper, we propose a novel mathematical framework for piecewise diffeomorphic image registration that involves discontinuous sliding motion using a diffeomorphism groupoid and algebroid approach. The traditional Large Deformation…

Group Theory · Mathematics 2026-04-30 Lili Bao , Bin Xiao , Shihui Ying , Stefan Sommer

The free-form deformation model can represent a wide range of non-rigid deformations by manipulating a control point lattice over the image. However, due to a large number of parameters, it is challenging to fit the free-form deformation…

Computer Vision and Pattern Recognition · Computer Science 2022-06-10 Takumi Nakane , Haoran Xie , Chao Zhang

Deformable registration of two-dimensional/three-dimensional (2D/3D) images of abdominal organs is a complicated task because the abdominal organs deform significantly and their contours are not detected in two-dimensional X-ray images. We…

Image and Video Processing · Electrical Eng. & Systems 2022-12-13 Ryuto Miura , Megumi Nakao , Mitsuhiro Nakamura , Tetsuya Matsuda

This paper describes an effective and efficient image classification framework nominated distributed deep representation learning model (DDRL). The aim is to strike the balance between the computational intensive deep learning approaches…

Computer Vision and Pattern Recognition · Computer Science 2016-07-05 Le Dong , Na Lv , Qianni Zhang , Shanshan Xie , Ling He , Mengdie Mao

Deformable image registration is fundamental to longitudinal and population analysis. Geometric alignment of the infant brain MR images is challenging, owing to rapid changes in image appearance in association with brain development. In…

Computer Vision and Pattern Recognition · Computer Science 2020-07-07 Dongming Wei , Sahar Ahmad , Yunzhi Huang , Lei Ma , Zhengwang Wu , Gang Li , Li Wang , Qian Wang , Pew-Thian Yap , Dinggang Shen

Registration is widely used in image-guided therapy and image-guided surgery to estimate spatial correspondences between organs of interest between planning and treatment images. However, while high-quality computed tomography (CT) images…

Image and Video Processing · Electrical Eng. & Systems 2022-03-11 Lin Tian , Connor Puett , Peirong Liu , Zhengyang Shen , Stephen R. Aylward , Yueh Z. Lee , Marc Niethammer

Segmentation maps of medical images annotated by medical experts contain rich spatial information. In this paper, we propose to decompose annotation maps to learn disentangled and richer feature transforms for segmentation problems in…

Image and Video Processing · Electrical Eng. & Systems 2019-06-10 Yizhe Zhang , Michael T. C. Ying , Danny Z. Chen

Image registration plays an important role in medical image analysis. Conventional optimization based methods provide an accurate estimation due to the iterative process at the cost of expensive computation. Deep learning methods such as…

Computer Vision and Pattern Recognition · Computer Science 2021-06-21 Junshen Xu , Eric Z. Chen , Xiao Chen , Terrence Chen , Shanhui Sun

The accuracy of deformable image registration (DIR) has a significant dosimetric impact in radiation treatment planning. We evaluated accuracy of various DIR algorithms using variations of the deformation point and volume. The reference…

We present a novel computational approach to fast and memory-efficient deformable image registration. In the variational registration model, the computation of the objective function derivatives is the computationally most expensive…

Computer Vision and Pattern Recognition · Computer Science 2018-04-30 Lars König , Jan Rühaak , Alexander Derksen , Jan Lellmann

We address the following problem: given two smooth densities on a manifold, find an optimal diffeomorphism that transforms one density into the other. Our framework builds on connections between the Fisher-Rao information metric on the…

Optimization and Control · Mathematics 2016-09-05 Martin Bauer , Sarang Joshi , Klas Modin

Deep learning has revolutionized image registration by its ability to handle diverse tasks while achieving significant speed advantages over conventional approaches. Current approaches, however, often employ globally uniform smoothness…

Computer Vision and Pattern Recognition · Computer Science 2025-09-22 Xiang Chen , Fengting Zhang , Qinghao Liu , Min Liu , Kun Wu , Yaonan Wang , Hang Zhang