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Many systems are modulated by unknown slow processes. This hinders analysis in highly non-linear systems, such as excitable systems. We show that for such systems, if the input matches the sparse `spiky' nature of the output, the spiking…

Neurons and Cognition · Quantitative Biology 2014-05-01 Daniel Soudry , Ron Meir

We report on a photo-induced transient state of YBa2Cu2O6+x in which transport perpendicular to the Cu-O planes becomes highly coherent. This effect is achieved by excitation with mid-infrared optical pulses, tuned to the resonant frequency…

Superconductivity · Physics 2014-06-04 S. Kaiser , C. R. Hunt , D. Nicoletti , W. Hu , I. Gierz , H. Y. Liu , M. Le Tacon , T. Loew , D. Haug , B. Keimer , A. Cavalleri

To improve artificial intelligence/autonomous systems and help with treating neurological conditions, there's a requirement for artificial neuron hardware that mimics biological. We examine experimental artificial neurons with quantum…

Quantum Physics · Physics 2024-01-03 Osama M. Nayfeh , Haik Manukian , Matthew Kelly , Justin Mauger

Emerging evidence shows that the modular organization of the human brain allows for better and efficient cognitive performance. Many of these cognitive functions are very fast and occur in subsecond time scale such as the visual object…

Neurons and Cognition · Quantitative Biology 2018-08-01 J. Rizkallah , P. Benquet , A. Kabbara , O. Dufor , F. Wendling , M. Hassan

Graph theoretical analyses of nervous systems usually omit the aspect of connection polarity, due to data insufficiency. The chemical synapse network of Caenorhabditis elegans is a well-reconstructed directed network, but the signs of its…

Molecular Networks · Quantitative Biology 2021-01-18 Bank G. Fenyves , Gabor S. Szilagyi , Zsolt Vassy , Csaba Soti , Peter Csermely

Recent electrophysiological experiments have shown that dopamine (D1) modulation of pyramidal cells in prefrontal cortex reduces spike frequency adaptation and enhances NMDA transmission. Using four models, from multicompartmental to…

Neurons and Cognition · Quantitative Biology 2017-12-12 Gabriele Scheler , Jean-Marc Fellous

Closed-loop neural interfaces with on-chip machine learning can detect and suppress disease symptoms in neurological disorders or restore lost functions in paralyzed patients. While high-density neural recording can provide rich neural…

Signal Processing · Electrical Eng. & Systems 2023-03-21 Uisub Shin , Cong Ding , Bingzhao Zhu , Yashwanth Vyza , Alix Trouillet , Emilie C. M. Revol , Stéphanie P. Lacour , Mahsa Shoaran

Biological systems sense and extract information from fluctuating signals while operating under energetic constraints and limited resolution. We introduce a general chemical model in which a sensor, coupled to a signaling pathway activated…

Statistical Mechanics · Physics 2025-12-09 Giorgio Nicoletti , Ivan Di Terlizzi , Daniel Maria Busiello

The neural dynamics of the nematode C. elegans are experimentally low-dimensional and correspond to discrete behavioral states, where previous modeling work has found neural proxies for some of these states. Experimental results further…

Neurons and Cognition · Quantitative Biology 2015-09-04 James Kunert , Eli Shlizerman , Andrew Walker , J. Nathan Kutz

Recordings from area V4 of monkeys have revealed that when the focus of attention is on a visual stimulus within the receptive field of a cortical neuron, two distinct changes can occur: The firing rate of the neuron can change and there…

Neurons and Cognition · Quantitative Biology 2007-05-23 Paul H. E. Tiesinga , Jean-Marc Fellous , Emilio Salinas , Jorge V. Jose , Terrence J. Sejnowski

The computation performed by a neuron can be formulated as a combination of dimensional reduction in stimulus space and the nonlinearity inherent in a spiking output. White noise stimulus and reverse correlation (the spike-triggered average…

Biological Physics · Physics 2007-05-23 Blaise Aguera y Arcas , Adrienne Fairhall

In the light of recent experimental findings that gap junctions are essential for low level intensity detection in the sensory periphery, the Greenberg-Hastings cellular automaton is employed to model the response of a two-dimensional…

Neurons and Cognition · Quantitative Biology 2016-09-08 Mauro Copelli , Osame Kinouchi

We present a method of estimating the gradient of an objective function with respect to the synaptic weights of a spiking neural network. The method works by measuring the fluctuations in the objective function in response to dynamic…

Neurons and Cognition · Quantitative Biology 2007-05-23 Ila R. Fiete , H. Sebastian Seung

Understanding how information about external stimuli is transformed into behavior is one of the central goals of neuroscience. Here we characterize the information flow through a complete sensorimotor circuit: from stimulus, to sensory…

Neurons and Cognition · Quantitative Biology 2015-10-15 Eduardo J. Izquierdo , Paul L. Williams , Randall D. Beer

Information integration from different modalities is an active area of research. Human beings and, in general, biological neural systems are quite adept at using a multitude of signals from different sensory perceptive fields to interact…

Neural and Evolutionary Computing · Computer Science 2021-10-05 Shiv Shankar

Local computation in microcircuits is an essential feature of distributed information processing in vertebrate and invertebrate brains. The insect antennal lobe represents a spatially confined local network that processes high-dimensional…

Neurons and Cognition · Quantitative Biology 2012-12-27 Anneke Meyer , Giovanni Galizia , Martin P. Nawrot

The concept of feature selectivity in sensory signal processing can be formalized as dimensionality reduction: in a stimulus space of very high dimensions, neurons respond only to variations within some smaller, relevant subspace. But if…

Neurons and Cognition · Quantitative Biology 2016-03-15 Kanaka Rajan , William Bialek

Foundation models have shown remarkable success in fitting biological visual systems; however, their black-box nature inherently limits their utility for understanding brain function. Here, we peek inside a SOTA foundation model of neural…

Neurons and Cognition · Quantitative Biology 2026-01-30 Johannes Bertram , Luciano Dyballa , Anderson Keller , Savik Kinger , Steven W. Zucker

Olfactory navigation is observed across species and plays a crucial role in locating resources for survival. In the laboratory, understanding the behavioral strategies and neural circuits underlying odor-taxis requires a detailed…

Neurons and Cognition · Quantitative Biology 2023-01-18 Kevin S. Chen , Rui Wu , Marc H. Gershow , Andrew M. Leifer

Insects identify and evaluate behaviorally relevant odorants in complex natural scenes where odor concentrations and mixture composition can change rapidly. In the honeybee, a combinatorial code of activated and inactivated projection…

Biological Physics · Physics 2011-01-06 Martin Paul Nawrot , Sabine Krofczik , Farzad Farkhooi , Randolf Menzel