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There is multiple databases contain datasets of TP53 gene and its tumor protein P53 which believed to be involved in over 50% of human cancers cases, these databases are rich as datasets covered all mutations caused diseases (cancers), but…

Computational Engineering, Finance, and Science · Computer Science 2015-05-27 Ayad Ghany Ismaeel , Raghad Zuhair Yousif

Tumor protein P53 is believed to be involved in over half of human cancers cases, the prediction of malignancies plays essential roles not only in advance detection for cancer, but also in discovering effective prevention and treatment of…

Computational Engineering, Finance, and Science · Computer Science 2013-10-09 Ayad Ghany Ismaeel

Determining the primary site of origin for metastatic tumors is one of the open problems in cancer care because the efficacy of treatment often depends on the cancer tissue of origin. Classification methods that can leverage tumor genomic…

Genomics · Quantitative Biology 2019-11-19 Alena Harley

With the increased affordability and availability of whole-genome sequencing, large-scale and high-throughput gene expression is widely used to characterize diseases, including cancers. However, establishing specificity in cancer diagnosis…

Machine Learning · Statistics 2018-12-21 Xi Chen , Jin Xie , Qingcong Yuan

In the current technological era, the medical profession has emerged as one of the researchers' favorite subject areas, and cancer is one of them. Because there is now no effective treatment for this illness, it is a matter of concern. Only…

Machine Learning · Computer Science 2024-10-23 Praneeth Kumar T , Nidhi Srivastava , Rakshith Mahishi , Chayadevi M L

Cancer is a term that denotes a group of diseases caused by abnormal growth of cells that can spread in different parts of the body. According to the World Health Organization (WHO), cancer is the second major cause of death after…

Machine Learning · Computer Science 2023-01-31 Fadi Alharbi , Aleksandar Vakanski

Machine learning can precisely identify different cancer tumors at any stage by classifying cancerous and healthy samples based on their genomic profile. We have developed novel methods of MLAC (Machine Learning Against Cancer) achieving…

Genomics · Quantitative Biology 2020-09-15 Arash Hooshmand

Background and Objective: Breast cancer, which accounts for 23% of all cancers, is threatening the communities of developing countries because of poor awareness and treatment. Early diagnosis helps a lot in the treatment of the disease. The…

Quantitative Methods · Quantitative Biology 2020-11-24 Hamza Saad , Nagendra Nagarur

Precise breast cancer classification on histopathological images has the potential to greatly improve the diagnosis and patient outcome in oncology. The data imbalance problem largely stems from the inherent imbalance within medical image…

Image and Video Processing · Electrical Eng. & Systems 2024-11-28 Majid Behzadpour , Bengie L. Ortiz , Ebrahim Azizi , Kai Wu

The discovery of important biomarkers is a significant step towards understanding the molecular mechanisms of carcinogenesis; enabling accurate diagnosis for, and prognosis of, a certain cancer type. Before recommending any diagnosis,…

Quantitative Methods · Quantitative Biology 2019-09-11 Md. Rezaul Karim , Michael Cochez , Oya Beyan , Stefan Decker , Christoph Lange

Breast cancer has long been a prominent cause of mortality among women. Diagnosis, therapy, and prognosis are now possible, thanks to the availability of RNA sequencing tools capable of recording gene expression data. Molecular subtyping…

Machine Learning · Computer Science 2021-11-11 Sheetal Rajpal , Virendra Kumar , Manoj Agarwal , Naveen Kumar

Background Precise prediction of cancer types is vital for cancer diagnosis and therapy. Important cancer marker genes can be inferred through predictive model. Several studies have attempted to build machine learning models for this task…

Genomics · Quantitative Biology 2019-06-20 Milad Mostavi , Yu-Chiao Chiu , Yufei Huang , Yidong Chen

Cancer and its subtypes constitute approximately 30% of all causes of death globally and display a wide range of heterogeneity in terms of clinical and molecular responses to therapy. Molecular subtyping has enabled the use of precision…

Quantitative Methods · Quantitative Biology 2024-07-11 Anwar Khan , Boreom Lee

Cancer is a complex genetic disease involving uncontrolled cell growth and proliferation, and necessitates effective targeting of dysregulated cellular pathways underlying cancer progression. Multiple genetic and epigenetic alterations…

Other Quantitative Biology · Quantitative Biology 2026-01-28 Manish Kumar

Late diagnosis and high costs are key factors that negatively impact the care of cancer patients worldwide. Although the availability of biological markers for the diagnosis of cancer type is increasing, costs and reliability of tests…

Machine Learning · Computer Science 2019-08-20 Sterling Ramroach , Melford John , Ajay Joshi

Breast cancer is one of the deadliest cancers causing about massive number of patients to die annually all over the world according to the WHO. It is a kind of cancer that develops when the tissues of the breast grow rapidly and unboundly.…

Computer Vision and Pattern Recognition · Computer Science 2025-01-22 Mst. Mumtahina Labonno , D. M. Asadujjaman , Md. Mahfujur Rahman , Abdullah Tamim , Mst. Jannatul Ferdous , Rafi Muttaki Mahi

Gene expression analysis is a critical method for cancer classification, enabling precise diagnoses through the identification of unique molecular signatures associated with various tumors. Identifying cancer-specific genes from gene…

Quantitative Methods · Quantitative Biology 2024-10-11 Farzana Tabassum , Sabrina Islam , Siana Rizwan , Masrur Sobhan , Tasnim Ahmed , Sabbir Ahmed , Tareque Mohmud Chowdhury

Prostate cancer is among the most common cancer in males and its heterogeneity is well known. Its early detection helps making therapeutic decision. There is no standard technique or procedure yet which is full-proof in predicting cancer…

Machine Learning · Computer Science 2018-12-18 Khalid Raza , Atif N Hasan

Oral cancer presents a formidable challenge in oncology, necessitating early diagnosis and accurate prognosis to enhance patient survival rates. Recent advancements in machine learning and data mining have revolutionized traditional…

Machine Learning · Computer Science 2025-06-13 Mohammad Subhi Al-Batah , Muhyeeddin Alqaraleh , Mowafaq Salem Alzboon

As much as data science is playing a pivotal role everywhere, healthcare also finds it prominent application. Breast Cancer is the top rated type of cancer amongst women; which took away 627,000 lives alone. This high mortality rate due to…

Machine Learning · Computer Science 2019-02-26 Vivek Kumar , Brojo Kishore Mishra , Manuel Mazzara , Dang N. H. Thanh , Abhishek Verma
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