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Tissue fluidity regulates many critical biological processes, including embryonic development, wound healing, and cancer metastasis. In confluent epithelia, where cell packing fraction is effectively fixed, the prevailing paradigm…

Biological Physics · Physics 2026-03-09 Pradip K. Bera , Anh Q. Nguyen , Molly McCord , Dapeng Bi , Jacob Notbohm

Engineering synthetic materials that mimic the remarkable complexity of living organisms is a fundamental challenge in science and technology. We study the spatiotemporal patterns that emerge when an active nematicfilm of microtubules and…

A theoretical model for stratified epithelium is presented. The viscoelastic properties of the tissue is assumed to be dependent on the spatial distribution of proliferative and differentiated cells. Based on this assumption, a hydrodynamic…

Biological Physics · Physics 2016-06-08 Wei-Ting Yeh , Hsuan-Yi Chen

The shear-thickening behaviour of wormlike micelles, at concentrations just below overlap, remains unexplained. In some cases it has recently been confirmed that very slow relaxations must be present even in the quiescent state -- for…

Soft Condensed Matter · Physics 2009-11-07 M. E. Cates , S. J. Candau

A minimalist simulation model for lipid bilayers is presented. Each lipid is represented by a flexible chain of beads in implicit solvent. The hydrophobic effect is mimicked through an intermolecular pair potential localized at the…

Statistical Mechanics · Physics 2009-11-11 Grace Brannigan , Peter F. Philips , Frank L. H. Brown

Lipid membranes form the barrier between the inside and outside of cells and many of their subcompartments. As such, they bind to a wide variety of nano- and micrometer sized objects and, in the presence of strong adhesive forces, strongly…

Soft Condensed Matter · Physics 2021-08-31 Hendrik T. Spanke , Jaime Agudo-Canalejo , Daniel Tran , Robert W. Style , Eric R. Dufresne

In biology, cells undergo deformations under the action of flow caused by the fluid surrounding them. These flows lead to shape changes and instabilities that have been explored in detail for single component vesicles. However, cell…

Fluid Dynamics · Physics 2025-10-15 Anirudh Venkatesh , Vivek Narsimhan

A coarse-grained molecular model, which consists of a spherical particle and an orientation vector, is proposed to simulate lipid membrane on a large length scale. The solvent is implicitly represented by an effective attractive interaction…

Soft Condensed Matter · Physics 2015-05-20 Hiroshi Noguchi

Metabolic substrates, such as oxygen and glucose, are rapidly delivered to the cell through filtration across microvessels walls. Modelling this important process is complicated by the coupling between flow and transport equations, which…

Subcellular Processes · Quantitative Biology 2013-08-12 Laura Facchini , Alberto Bellin , Eleuterio F. Toro

The phase behavior of colloidal particles embedded in a binary fluid is influenced by wetting layers surrounding each particle. The free energy of the fluid film depends on its morphology, i.e., on size, shape and connectivity. Under rather…

Soft Condensed Matter · Physics 2007-05-23 Uwe Brodatzki , Klaus Mecke

Morphogenetic dynamics of tissue sheets require coordinated cell shape changes regulated by global patterning of mechanical forces. Inspired by such biological phenomena, we propose a minimal mechanochemical model based on the notion that…

Soft Condensed Matter · Physics 2021-01-01 Andrei Zakharov , Kinjal Dasbiswas

Within the framework of the well-known curvature models, a fluid lipid bilayer membrane is regarded as a surface embedded in the three-dimensional Euclidean space whose equilibrium shapes are described in terms of its mean and Gaussian…

Mathematical Physics · Physics 2009-10-22 V. M. Vassilev , P. A. Djondjorov , I. M. Mladenov

Molecules at the air-water interface often form inhomogeneous layers in which domains of different densities are separated by sharp interfaces. Complex interfacial pattern formation may occur through the competition of short- and long-range…

patt-sol · Physics 2009-10-30 David K. Lubensky , Raymond E. Goldstein

The dynamics of a membrane is a coupled system comprising a moving elastic surface and an incompressible membrane fluid. We will consider a reduced elastic surface model, which involves the evolution equations of the moving surface, the…

Analysis of PDEs · Mathematics 2015-05-27 Wei Wang , Pingwen Zhang , Zhifei Zhang

Surface active ionic liquids (SAILs) combine useful characteristics of both ionic liquids (ILs) and surfactants, hence are promising candidates for a wide range of applications. However, the effect of SAIL ionic structures on their…

The Fluid Mosaic Model by Singer & Nicolson proposes that biological membranes consist of a fluid lipid layer into which integral proteins are embedded. The lipid membrane acts as a two-dimensional liquid in which the proteins can diffuse…

Biological Physics · Physics 2025-09-29 Thomas Heimburg

Vesicles self-assembled from amphiphilic diblock copolymers exhibit a wide diversity of behavior upon electroporation, due to competitions between edge, surface and bending energies that drive the system, while different viscous dissipation…

Soft Condensed Matter · Physics 2009-11-07 Harry Bermudez , Helim Aranda-Espinoza , Daniel A. Hammer , Dennis E. Discher , .

We analyze the aggregation of locally amphiphilic copolymers with blocky architecture and uniformly distributed amphiphilic moieties in terms of a mean-field theory. Locally amphiphilic structure is characteristic of many thermoresponsive…

Soft Condensed Matter · Physics 2024-12-31 S. A. Pavlenko , E. N. Govorun

We report experiments investigating the behaviour of micron-scale fluid droplets jetted onto surfaces patterned with lyophobic and lyophilic stripes. The final droplet shape depends on the droplet size relative to that of the stripes. In…

Soft Condensed Matter · Physics 2007-05-23 J. Leopoldes , A. Dupuis , D. G. Bucknall , J. M. Yeomans

We have studied by Molecular Dynamics computer simulations the dynamics of water confined in ionic surfactants phases, ranging from well ordered lamellar structures to micelles at low and high water loading, respectively. We have analysed…

Soft Condensed Matter · Physics 2016-03-23 Samuel Hanot , Sandrine Lyonnard , Stefano Mossa
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