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Melanoma is one of the most aggressive forms of skin cancer, causing a large proportion of skin cancer deaths. However, melanoma diagnoses by pathologists shows low interrater reliability. As melanoma is a cancer of the melanocyte, there is…

Quantitative Methods · Quantitative Biology 2024-03-15 Mikio Tada , Ursula E. Lang , Iwei Yeh , Elizabeth S. Keiser , Maria L. Wei , Michael J. Keiser

The immunohistochemical (IHC) staining of the human epidermal growth factor receptor 2 (HER2) biomarker is widely practiced in breast tissue analysis, preclinical studies and diagnostic decisions, guiding cancer treatment and investigation…

Skin cancer is among the most common cancer types. Dermoscopic image analysis improves the diagnostic accuracy for detection of malignant melanoma and other pigmented skin lesions when compared to unaided visual inspection. Hence,…

Computer Vision and Pattern Recognition · Computer Science 2020-06-29 Amirreza Mahbod , Gerald Schaefer , Chunliang Wang , Rupert Ecker , Georg Dorffner , Isabella Ellinger

The advent of deep learning has significantly propelled the capabilities of automated medical image diagnosis, providing valuable tools and resources in the realm of healthcare and medical diagnostics. This research delves into the…

Image and Video Processing · Electrical Eng. & Systems 2023-11-20 Ryan Donghan Kwon , Dohyun Lim , Yoonha Lee , Seung Won Lee

Skin cancer is a serious worldwide health issue, precise and early detection is essential for better patient outcomes and effective treatment. In this research, we use modern deep learning methods and explainable artificial intelligence…

Image and Video Processing · Electrical Eng. & Systems 2023-12-19 Faysal Mahmud , Md. Mahin Mahfiz , Md. Zobayer Ibna Kabir , Yusha Abdullah

In recent years, the incidence of vision-threatening eye diseases has risen dramatically, necessitating scalable and accurate screening solutions. This paper presents a comprehensive study on deep learning architectures for the automated…

Computer Vision and Pattern Recognition · Computer Science 2025-12-12 Mohammad Sadegh Gholizadeh , Amir Arsalan Rezapour

Deep learning models have gained increasing adoption in medical image analysis. However, these models often produce overconfident predictions, which can compromise clinical accuracy and reliability. Bridging the gap between high-performance…

Image and Video Processing · Electrical Eng. & Systems 2026-03-24 Jutika Borah , Hidam Kumarjit Singh

Fine-grained classification of cervical cells into different abnormality levels is of great clinical importance but remains very challenging. Contrary to traditional classification methods that rely on hand-crafted or engineered features,…

Computer Vision and Pattern Recognition · Computer Science 2018-10-16 Haoming Lin , Yuyang Hu , Siping Chen , Jianhua Yao , Ling Zhang

Digital pathology and microscopy image analysis are widely employed in the segmentation of digitally scanned IHC slides, primarily to identify cancer and pinpoint regions of interest (ROI) indicative of tumor presence. However, current ROI…

Computer Vision and Pattern Recognition · Computer Science 2024-06-11 Akash Modi , Sumit Kumar Jha , Purnendu Mishra , Rajiv Kumar , Kiran Aatre , Gursewak Singh , Shubham Mathur

Histopathological images are widely used for the analysis of diseased (tumor) tissues and patient treatment selection. While the majority of microscopy image processing was previously done manually by pathologists, recent advances in…

Image and Video Processing · Electrical Eng. & Systems 2024-07-12 Andrey Ignatov , Josephine Yates , Valentina Boeva

Purpose: We aimed to develop deep machine learning (DL) models to improve the detection and segmentation of intraprostatic lesions (IL) on bp-MRI by using whole amount prostatectomy specimen-based delineations. We also aimed to investigate…

Image and Video Processing · Electrical Eng. & Systems 2020-10-30 Zhenzhen Dai , Ivan Jambor , Pekka Taimen , Milan Pantelic , Mohamed Elshaikh , Craig Rogers , Otto Ettala , Peter Boström , Hannu Aronen , Harri Merisaari , Ning Wen

Skin cancer is a fatal manifestation of cancer. Unrepaired deoxyribo-nucleic acid (DNA) in skin cells, causes genetic defects in the skin and leads to skin cancer. To deal with lethal mortality rates coupled with skyrocketing costs of…

Computer Vision and Pattern Recognition · Computer Science 2022-11-22 Sanya Sinha , Nilay Gupta

The rapid development in representation learning techniques such as deep neural networks and the availability of large-scale, well-annotated medical imaging datasets have to a rapid increase in the use of supervised machine learning in the…

Computer Vision and Pattern Recognition · Computer Science 2023-04-19 Dat T. Ngo , Thao T. B. Nguyen , Hieu T. Nguyen , Dung B. Nguyen , Ha Q. Nguyen , Hieu H. Pham

Computer-aided histopathological image analysis for cancer detection is a major research challenge in the medical domain. Automatic detection and classification of nuclei for cancer diagnosis impose a lot of challenges in developing state…

Computer Vision and Pattern Recognition · Computer Science 2022-02-22 Suvidha Tripathi , Satish Kumar Singh

The Deep Convolutional Neural Network (DCNN) is one of the most powerful and successful deep learning approaches. DCNNs have already provided superior performance in different modalities of medical imaging including breast cancer…

Computer Vision and Pattern Recognition · Computer Science 2018-11-13 Md Zahangir Alom , Chris Yakopcic , Tarek M. Taha , Vijayan K. Asari

Breast cancer, the most common malignancy among women, requires precise detection and classification for effective treatment. Immunohistochemistry (IHC) biomarkers like HER2, ER, and PR are critical for identifying breast cancer subtypes.…

Computer Vision and Pattern Recognition · Computer Science 2025-03-31 Ekansh Chauhan , Anila Sharma , Amit Sharma , Vikas Nishadham , Asha Ghughtyal , Ankur Kumar , Gurudutt Gupta , Anurag Mehta , C. V. Jawahar , P. K. Vinod

Treatment approaches for colorectal cancer (CRC) are highly dependent on the molecular subtype, as immunotherapy has shown efficacy in cases with microsatellite instability (MSI) but is ineffective for the microsatellite stable (MSS)…

Computer Vision and Pattern Recognition · Computer Science 2024-11-13 Hadar Hezi , Matan Gelber , Alexander Balabanov , Yosef E. Maruvka , Moti Freiman

This study evaluates the reliability of two deep learning models for skin cancer detection, focusing on their explainability and fairness. Using the HAM10000 dataset of dermatoscopic images, the research assesses two convolutional neural…

Image and Video Processing · Electrical Eng. & Systems 2024-09-09 Tanish Jain

Skin cancer is a global health concern, necessitating early and accurate diagnosis for improved patient outcomes. This study introduces a groundbreaking approach to skin cancer classification, employing the Vision Transformer, a…

Image and Video Processing · Electrical Eng. & Systems 2024-01-11 Galib Muhammad Shahriar Himel , Md. Masudul Islam , Kh Abdullah Al-Aff , Shams Ibne Karim , Md. Kabir Uddin Sikder

Deep neural networks have demonstrated promising performance on image recognition tasks. However, they may heavily rely on confounding factors, using irrelevant artifacts or bias within the dataset as the cue to improve performance. When a…

Computer Vision and Pattern Recognition · Computer Science 2023-03-03 Siyuan Yan , Zhen Yu , Xuelin Zhang , Dwarikanath Mahapatra , Shekhar S. Chandra , Monika Janda , Peter Soyer , Zongyuan Ge
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