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Over the past few years, there has been a considerable spread of microarray technology in many biological patterns, particularly in those pertaining to cancer diseases like leukemia, prostate, colon cancer, etc. The primary bottleneck that…

Quantitative Methods · Quantitative Biology 2020-07-20 Parth Patel , Kalpdrum Passi , Chakresh Kumar Jain

Nonnegative Matrix Factorization (NMF) is a widely used technique for data representation. Inspired by the expressive power of deep learning, several NMF variants equipped with deep architectures have been proposed. However, these methods…

Machine Learning · Computer Science 2017-11-21 Yuning Qiu , Guoxu Zhou , Kan Xie

We propose a combined model, which integrates the latent factor model and the logistic regression model, for the citation network. It is noticed that neither a latent factor model nor a logistic regression model alone is sufficient to…

Machine Learning · Statistics 2019-12-03 Namjoon Suh , Xiaoming Huo , Eric Heim , Lee Seversky

Nonnegative Matrix Factorization (NMF) is the problem of approximating a nonnegative matrix with the product of two low-rank nonnegative matrices and has been shown to be particularly useful in many applications, e.g., in text mining, image…

Optimization and Control · Mathematics 2012-08-13 Nicolas Gillis , François Glineur

It is more and more common to explore the genome at diverse levels and not only at a single omic level. Through integrative statistical methods, omics data have the power to reveal new biological processes, potential biomarkers, and…

Methodology · Statistics 2021-03-05 Morgane Pierre-Jean , Florence Mauger , Jean-François Deleuze , Edith Le Floch

Extracting genetic information from a full range of sequencing data is important for understanding diseases. We propose a novel method to effectively explore the landscape of genetic mutations and aggregate them to predict cancer type. We…

Genomics · Quantitative Biology 2018-10-10 Zexian Zeng , Andy Vo , Chengsheng Mao , Susan E Clare , Seema A Khan , Yuan Luo

Topic modeling is a technique for organizing and extracting themes from large collections of unstructured text. Non-negative matrix factorization (NMF) is a common unsupervised approach that decomposes a term frequency-inverse document…

Machine Learning · Computer Science 2024-07-30 Selma Wanna , Ryan Barron , Nick Solovyev , Maksim E. Eren , Manish Bhattarai , Kim Rasmussen , Boian S. Alexandrov

Most existing methods for biomedical entity recognition task rely on explicit feature engineering where many features either are specific to a particular task or depends on output of other existing NLP tools. Neural architectures have been…

Computation and Language · Computer Science 2017-08-14 Sunil Kumar Sahu , Ashish Anand

The symmetric Nonnegative Matrix Factorization (NMF), a special but important class of the general NMF, has found numerous applications in data analysis such as various clustering tasks. Unfortunately, designing fast algorithms for the…

Machine Learning · Computer Science 2023-01-26 Xiao Li , Zhihui Zhu , Qiuwei Li , Kai Liu

Nonnegative matrix factorization (NMF) seeks a low-rank approximation $X \approx UV^T$ with nonnegative factors and is commonly solved using interior methods that enforce feasibility throughout optimization. We show that such…

Machine Learning · Computer Science 2026-05-20 Qiujing Lu , Tonmoy Monsoor , Ehsan Ebrahimzadeh , Kartik Sharma , Vwani Roychowdhury

Latent feature models (LFM)s are widely employed for extracting latent structures of data. While offering high, parameter estimation is difficult with LFMs because of the combinational nature of latent features, and non-identifiability is a…

Machine Learning · Computer Science 2018-09-27 Ryota Suzuki , Shingo Takahashi , Murtuza Petladwala , Shigeru Kohmoto

We show how to incorporate information from labeled examples into nonnegative matrix factorization (NMF), a popular unsupervised learning algorithm for dimensionality reduction. In addition to mapping the data into a space of lower…

Machine Learning · Computer Science 2011-12-19 Youngmin Cho , Lawrence K. Saul

We present a hybrid method for latent information discovery on the data sets containing both text content and connection structure based on constrained low rank approximation. The new method jointly optimizes the Nonnegative Matrix…

Machine Learning · Computer Science 2017-03-29 Rundong Du , Barry Drake , Haesun Park

Various Non-negative Matrix factorization (NMF) based methods add new terms to the cost function to adapt the model to specific tasks, such as clustering, or to preserve some structural properties in the reduced space (e.g., local…

Nonnegative matrix factorization (NMF) is a known unsupervised data-reduction method. The principle of the common cause (PCC) is a basic methodological approach in probabilistic causality, which seeks an independent mixture model for the…

Machine Learning · Computer Science 2025-09-09 E. Khalafyan , A. E. Allahverdyan , A. Hovhannisyan

In this paper we consider the Nonnegative Matrix Factorization (NMF) problem: given an (elementwise) nonnegative matrix $V \in \R_+^{m\times n}$ find, for assigned $k$, nonnegative matrices $W\in\R_+^{m\times k}$ and $H\in\R_+^{k\times n}$…

Optimization and Control · Mathematics 2014-07-08 Lorenzo Finesso , Peter Spreij

Non-negative matrix factorization (NMF) has become a popular machine learning approach to many problems in text mining, speech and image processing, bio-informatics and seismic data analysis to name a few. In NMF, a matrix of non-negative…

Numerical Analysis · Computer Science 2013-03-19 Hugo Van hamme

Motivated by the problem of identifying potential hierarchical population structure on modern survey data containing a wide range of complex data types, we introduce population-based hierarchical non-negative matrix factorization (PHNMF).…

Nonnegative Matrix Factorization (NMF) is a widely applied technique in the fields of machine learning and data mining. Graph Regularized Non-negative Matrix Factorization (GNMF) is an extension of NMF that incorporates graph regularization…

Machine Learning · Computer Science 2024-03-19 Zhen Wang , Wenwen Min

Nonnegative matrix factorization (NMF) is widely used for clustering with strong interpretability. Among general NMF problems, symmetric NMF is a special one that plays an important role in graph clustering where each element measures the…

Machine Learning · Computer Science 2023-11-07 Mengyuan Zhang , Kai Liu
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