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Precision medicine emerges as the most important contemporary paradigm shift of medical practice but has several challenges in evidence formation and implementation for clinical practice. Precision/Personalized evidence-based medicine…

Other Quantitative Biology · Quantitative Biology 2015-12-15 Maani Beigy

In many contexts Gaussian Mixtures (GM) are used to approximate probability distributions, possibly time-varying. In some applications the number of GM components exponentially increases over time, and reduction procedures are required to…

Machine Learning · Statistics 2021-04-27 A. D'Ortenzio , C. Manes

In many applications involving multi-media data, the definition of similarity between items is integral to several key tasks, e.g., nearest-neighbor retrieval, classification, and recommendation. Data in such regimes typically exhibits…

Artificial Intelligence · Computer Science 2010-09-01 Brian McFee , Gert Lanckriet

Accurate approximation of probability measures is essential in numerical applications. This paper explores the quantization of probability measures using the maximum mean discrepancy (MMD) distance as a guiding metric. We first investigate…

Optimization and Control · Mathematics 2025-03-18 Zahra Mehraban , Alois Pichler

We present simple, user-friendly bounds for the expected operator norm of a random kernel matrix under general conditions on the kernel function $k(\cdot,\cdot)$. Our approach uses decoupling results for U-statistics and the non-commutative…

Machine Learning · Statistics 2025-11-07 Chiraag Kaushik , Justin Romberg , Vidya Muthukumar

Monotonicity constraints are powerful regularizers in statistical modelling. They can support fairness in computer-aided decision making and increase plausibility in data-driven scientific models. The seminal min-max (MM) neural network…

Machine Learning · Computer Science 2024-05-28 Christian Igel

Many interesting machine learning problems are best posed by considering instances that are distributions, or sample sets drawn from distributions. Previous work devoted to machine learning tasks with distributional inputs has done so…

Machine Learning · Statistics 2021-01-15 Danica J. Sutherland , Junier B. Oliva , Barnabás Póczos , Jeff Schneider

Generalized empirical likelihood and generalized method of moments are well spread methods of resolution of inverse problems in econometrics. Each method defines a specific semiparametric model for which it is possible to calculate…

Statistics Theory · Mathematics 2010-11-24 Paul Rochet

Gaussian processes (GP) for machine learning have been studied systematically over the past two decades and they are by now widely used in a number of diverse applications. However, GP kernel design and the associated hyper-parameter…

Machine Learning · Computer Science 2020-10-28 Feng Yin , Lishuo Pan , Xinwei He , Tianshi Chen , Sergios Theodoridis , Zhi-Quan , Luo

Understanding and developing a correlation measure that can detect general dependencies is not only imperative to statistics and machine learning, but also crucial to general scientific discovery in the big data age. In this paper, we…

Machine Learning · Statistics 2024-06-27 Cencheng Shen , Carey E. Priebe , Joshua T. Vogelstein

Distributionally robust optimization (DRO) has attracted attention in machine learning due to its connections to regularization, generalization, and robustness. Existing work has considered uncertainty sets based on phi-divergences and…

Machine Learning · Computer Science 2019-05-28 Matthew Staib , Stefanie Jegelka

Kernel two-sample tests have been widely used for multivariate data to test equality of distributions. However, existing tests based on mapping distributions into a reproducing kernel Hilbert space mainly target specific alternatives and do…

Methodology · Statistics 2023-11-21 Hoseung Song , Hao Chen

Generalized linear mixed-effects models (GLMMs) are widely used to analyze grouped and hierarchical data. In a GLMM, each response is assumed to follow an exponential-family distribution where the natural parameter is given by a linear…

Machine Learning · Statistics 2026-04-14 Yuli Slavutsky , Sebastian Salazar , David M. Blei

Generalized linear mixed models are powerful tools for analyzing clustered data, where the unknown parameters are classically (and most commonly) estimated by the maximum likelihood and restricted maximum likelihood procedures. However,…

Statistics Theory · Mathematics 2023-03-23 Andrea M. Bratsberg , Magne Thoresen , Abhik Ghosh

Given the increasing popularity of algorithms for overlapping clustering, in particular in social network analysis, quantitative measures are needed to measure the accuracy of a method. Given a set of true clusters, and the set of clusters…

Physics and Society · Physics 2013-08-05 Aaron F. McDaid , Derek Greene , Neil Hurley

Generalized linear mixed models (GLMMs) are used to model responses from exponential families with a combination of fixed and random effects. For variance components in GLMMs, we propose an approximate restricted likelihood ratio test that…

Methodology · Statistics 2019-06-11 Stephanie T. Chen , Luo Xiao , Ana-Maria Staicu

Statistical machine learning plays an important role in modern statistics and computer science. One main goal of statistical machine learning is to provide universally consistent algorithms, i.e., the estimator converges in probability or…

Machine Learning · Statistics 2016-04-18 Andreas Christmann , Florian Dumpert , Dao-Hong Xiang

We propose a new metric ($m$-coherence) to experimentally study the alignment of per-example gradients during training. Intuitively, given a sample of size $m$, $m$-coherence is the number of examples in the sample that benefit from a small…

Machine Learning · Computer Science 2020-08-05 Satrajit Chatterjee , Piotr Zielinski

Machine learning (ML) models, such as SVM, for tasks like classification and clustering of sequences, require a definition of distance/similarity between pairs of sequences. Several methods have been proposed to compute the similarity…

Machine Learning · Computer Science 2022-09-13 Sarwan Ali , Bikram Sahoo , Muhammad Asad Khan , Alexander Zelikovsky , Imdad Ullah Khan , Murray Patterson

Similarity learning has received a large amount of interest and is an important tool for many scientific and industrial applications. In this framework, we wish to infer the distance (similarity) between points with respect to an arbitrary…

Machine Learning · Statistics 2016-11-30 Michael Rabadi