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Patients with epilepsy can manifest short, sub-clinical epileptic "bursts" in addition to full-blown clinical seizures. We believe the relationship between these two classes of events---something not previously studied…

Machine Learning · Statistics 2014-07-29 Drausin F. Wulsin , Emily B. Fox , Brian Litt

We present a hybrid scheme for the parameter and state estimation of nonlinear continuous-time systems, which is inspired by the supervisory setup used for control. State observers are synthesized for some nominal parameter values and a…

Optimization and Control · Mathematics 2016-11-18 Michelle S. Chong , Dragan Nešić , Romain Postoyan , Levin Kuhlmann

A central challenge in neuroscience is understanding how neural system implements computation through its dynamics. We propose a nonlinear time series model aimed at characterizing interpretable dynamics from neural trajectories. Our model…

Quantitative Methods · Quantitative Biology 2016-10-28 Yuan Zhao , Il Memming Park

In the dynamic hospital setting, decision support can be a valuable tool for improving patient outcomes. Data-driven inference of future outcomes is challenging in this dynamic setting, where long sequences such as laboratory tests and…

Quantitative Methods · Quantitative Biology 2024-04-25 Alan D. Kaplan , Priyadip Ray , John D. Greene , Vincent X. Liu

The advent of dispersion-engineered and highly nonlinear nanophotonics is expected to open up an all-optical path towards the strong-interaction regime of quantum optics by combining high transverse field confinement with ultra-short-pulse…

Quantum Physics · Physics 2021-03-09 Ryotatsu Yanagimoto , Edwin Ng , Tatsuhiro Onodera , Hideo Mabuchi

Currently, many critical care indices are repetitively assessed and recorded by overburdened nurses, e.g. physical function or facial pain expressions of nonverbal patients. In addition, many essential information on patients and their…

Dynamic prediction of causal effects under different treatment regimes conditional on an individual's characteristics and longitudinal history is an essential problem in precision medicine. This is challenging in practice because outcomes…

Methodology · Statistics 2023-03-07 Yizhen Xu , Jisoo Kim , Laura K. Hummers , Ami A. Shah , Scott Zeger

In the present paper, two existing nonlinear system identification methodologies are used to identify data-driven models. The first methodology focuses on identifying the system using steady-state excitations. To accomplish this, a…

Systems and Control · Electrical Eng. & Systems 2020-11-18 Maren Scheel , Gleb Kleyman , Ali Tatar , Matthew R. W. Brake , Simon Peter , Jean-Philippe Noël , Matthew S. Allen , Malte Krack

The intensive care unit (ICU) is a specialized hospital space where critically ill patients receive intensive care and monitoring. Comprehensive monitoring is imperative in assessing patients conditions, in particular acuity, and ultimately…

Artificial Intelligence · Computer Science 2024-11-25 Subhash Nerella , Ziyuan Guan , Scott Siegel , Jiaqing Zhang , Ruilin Zhu , Kia Khezeli , Azra Bihorac , Parisa Rashidi

In this paper, we investigate induced and nonlinear fiber topological pressure for random dynamical systems. We define a non-averaged induced fiber pressure via spanning and separated sets, characterize it as the pseudo-inverse of the…

Dynamical Systems · Mathematics 2026-04-17 Cunyi Nan

Owing to the recent advancements in wearable devices for health care, the importance of BP estimation without cuffs increases. Cuff technologies are inappropriate for continuous BP measurement due to their inconvenient usage, invasive…

Signal Processing · Electrical Eng. & Systems 2026-05-05 Vaibhav Gollapalli , Aniruth Ananthanarayanan

In nonlinear dynamical systems with highly nonorthogonal linear eigenvectors, linear non-modal analysis is more useful than normal mode analysis in predicting turbulent properties. However, the non-trivial time evolution of non-modal…

Plasma Physics · Physics 2015-06-22 Brett Friedman , Troy A. Carter

This study investigates the paradigm of intraoperative analgesic dosage using a data-driven approach based on retrospective clinical data. Remifentanil, an analgesic widely used during anesthesia, presents a dosing challenge due to the…

Signal Processing · Electrical Eng. & Systems 2025-12-23 Bob Aubouin-Pairault , Mazen Alamir , Benjamin Meyer , Rémi Wolf , Kaouther Moussa

Neural network modules conditioned by known priors can be effectively trained and combined to represent systems with nonlinear dynamics. This work explores a novel formulation for data-efficient learning of deep control-oriented nonlinear…

Dynamical Systems · Mathematics 2021-01-07 Elliott Skomski , Soumya Vasisht , Colby Wight , Aaron Tuor , Jan Drgona , Draguna Vrabie

In this paper, several advanced data-driven nonlinear identification techniques are compared on a specific problem: a simplified glucoregulatory system modeling example. This problem represents a challenge in the development of an…

Systems and Control · Computer Science 2018-04-20 Anna Marconato , Maarten Schoukens , Koen Tiels , W. Dhammika Widanage , Amjad Abu-Rmileh , Johan Schoukens

This paper presents a novel mechatronic setup intended for providing respiratory support to patients suffering from pulmonary failure. The setup relies upon the circulation of an oxygenated perfluorocarbon (PFC) through the abdominal…

Objective: realtime monitoring of invasive ventilation (iV) in intensive care units (ICUs) plays a crucial role in ensuring prompt interventions and better patient outcomes. However, conventional methods often overlook valuable insights…

Computation and Language · Computer Science 2024-10-08 Arash Pakbin , Aaron Su , Donald K. K. Lee , Bobak J. Mortazavi

Probing signal injection is a well-established technique to extract additional information from a weakly (or non) observable dynamical system. Using averaging theory, a framework to analyse such schemes for general nonlinear systems has…

Systems and Control · Computer Science 2019-11-20 Bowen Yi , Romeo Ortega , Houria Siguerdidjane , Juan E. Machado , Weidong Zhang

Nonlinear dynamics can impact the performance of a particle accelerator in a number of different ways, depending on the type of the accelerator and the parameter regime in which it operates. Effects can range from minor changes in beam…

Accelerator Physics · Physics 2022-01-06 H. Bartosik , Y. Papaphilippou , A. Wolski

The ability to robustly and efficiently control the dynamics of nonlinear systems lies at the heart of many current technological challenges, ranging from drug delivery systems to ensuring flight safety. Most such scenarios are too complex…

Fluid Dynamics · Physics 2021-02-16 Radu Cimpeanu , Susana N. Gomes , Demetrios T. Papageorgiou