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Significant intra-observer and inter-observer variability in the interpretation of coronary angiograms are reported. This variability is in part due to the common practices that rely on performing visual inspections by specialists (e.g.,…
Coronary artery disease leading up to stenosis, the partial or total blocking of coronary arteries, is a severe condition that affects millions of patients each year. Automated identification and classification of stenosis severity from…
Computed Tomography Coronary Angiography (CTCA) is a non-invasive method to evaluate coronary artery anatomy and disease. CTCA is ideal for geometry reconstruction to create virtual models of coronary arteries. To our knowledge there is no…
We propose a new iterative segmentation model which can be accurately learned from a small dataset. A common approach is to train a model to directly segment an image, requiring a large collection of manually annotated images to capture the…
Coronary artery diseases are among the leading causes of mortality worldwide. Timely and accurate diagnosis, facilitated by precise coronary artery segmentation, is pivotal in changing patient outcomes. In the realm of biomedical imaging,…
Accurate cerebrovascular segmentation from Magnetic Resonance Angiography (MRA) and Computed Tomography Angiography (CTA) is of great significance in diagnosis and treatment of cerebrovascular pathology. Due to the complexity and topology…
More than 13 million people suffer from ischemic cerebral stroke worldwide each year. Thrombolytic treatment can reduce brain damage but has a narrow treatment window. Computed Tomography Perfusion imaging is a commonly used primary…
Advances in image registration and machine learning have recently enabled volumetric analysis of postmortem brain tissue from conventional photographs of coronal slabs, which are routinely collected in brain banks and neuropathology…
Coronary stenosis is a major risk factor for ischemic heart events leading to increased mortality, and medical treatments for this condition require meticulous, labor-intensive analysis. Coronary angiography provides critical visual cues…
Automatic labelling of anatomical structures, such as coronary arteries, is critical for diagnosis, yet existing (non-deep learning) methods are limited by a reliance on prior topological knowledge of the expected tree-like structures. As…
Acute Coronary Syndrome (ACS) is a syndrome caused by a decrease in blood flow in the coronary arteries. The ACS is usually related to coronary thrombosis and is primarily caused by plaque rupture followed by plaque erosion and calcified…
Medical image segmentation is one of the important tasks of computer-aided diagnosis in medical image analysis. Since most medical images have the characteristics of blurred boundaries and uneven intensity distribution, through existing…
Segmentation of the aorta is crucial for various medical analyses, such as the diagnosis and treatment of cardiovascular diseases. This work presents mathematical models and methods yielding a semi-automatic segmentation of the aorta from…
In the era of digital medicine, medical imaging serves as a widespread technique for early disease detection, with a substantial volume of images being generated and stored daily in electronic patient records. X-ray angiography imaging is a…
Coronary artery disease (CAD) remains a leading cause of mortality worldwide, requiring accurate segmentation and stenosis detection using Coronary Computed Tomography angiography (CCTA). Existing methods struggle with challenges such as…
Existing methods to reconstruct vascular structures from a computed tomography (CT) angiogram rely on injection of intravenous contrast to enhance the radio-density within the vessel lumen. However, pathological changes can be present in…
Heart disease is one of the most common diseases in middle-aged citizens. Among the vast number of heart diseases, the coronary artery disease (CAD) is considered as a common cardiovascular disease with a high death rate. The most popular…
The analysis of carotid arteries, particularly plaques, in multi-sequence Magnetic Resonance Imaging (MRI) data is crucial for assessing the risk of atherosclerosis and ischemic stroke. In order to evaluate metrics and radiomic features,…
The three-dimensional vascular model reconstructed from CT images is widely used in medical diagnosis. At different phases, the beating of the heart can cause deformation of vessels, resulting in different vascular imaging states and false…
Fetal cortical plate segmentation is essential in quantitative analysis of fetal brain maturation and cortical folding. Manual segmentation of the cortical plate, or manual refinement of automatic segmentations is tedious and…