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Partitioning and transport of water and small solutes into and through nanopores is important to a variety of chemical and biological processes and applications. Here we study the partitioning of positive ions of increasing size into the…

Chemical Physics · Physics 2007-05-23 Lu Yang , Shekhar Garde

We investigate a model nanopore sensor that is able to detect analyte ions that are present in the electrolyte solution in very small concentrations. The nanopore selectively binds the analyte ions with which the local concentrations of the…

Applied Physics · Physics 2018-12-31 Eszter Mádai , Mónika Valiskó , Dezső Boda

Interfacial interactions significantly alter the fundamental properties of water confined in mesoporous structures, with crucial implications for geological, physicochemical, and biological processes. Herein, we focused on the effect of…

Water mediates electrostatic interactions via the orientation of its dipoles around ions, molecules, and interfaces. This induced water polarization consequently influences multiple phenomena. In particular, water polarization modulated by…

Ionic Current Rectification (ICR) can appear in nanopores, causing a diode-like behavior that originates from different efficiency of ion transport through the pore channel with respect to the applied voltage bias polarity. This effect is…

Graphene-based laminates, with ultralong and tortuous nanocapillaries formed by simply stacking graphene flakes together, have great promises in filtration and separation. However, the information on liquid water trans-membrane permeation…

Chemical Physics · Physics 2015-02-11 Pengzhan Sun , He Liu , Kunlin Wang , Minlin Zhong , Dehai Wu , Hongwei Zhu

Biological ion channels balance electrostatic and dehydration effects to yield large ion selectivities alongside high transport rates. These macromolecular systems are often interrogated through point mutations of their pore domain,…

Mesoscale and Nanoscale Physics · Physics 2019-07-19 Subin Sahu , Justin Elenewski , Christoph Rohmann , Michael Zwolak

Molecular dynamics (MD) simulations were performed to study the formation process of nanopores in a suspended graphene sheet irradiated by using energetic ions though a mask. By controlling the ion parameters including mass, energy and…

Mesoscale and Nanoscale Physics · Physics 2016-03-10 Weisen Li , Li Liang , Shijun Zhao , Shuo zhang , Jianming Xue

We report Molecular Dynamics (MD) simulations of a generic hydrophobic nanopore connecting two reservoirs which are initially at different Na+ concentrations, as in a biological cell. The nanopore is impermeable to water under equilibrium…

Biological Physics · Physics 2009-11-10 J. Dzubiella , R. J. Allen , J. -P. Hansen

Isolated, atomically thin conducting membranes of graphite, called graphene, have recently been the subject of intense research with the hope that practical applications in fields ranging from electronics to energy science will emerge.…

Mesoscale and Nanoscale Physics · Physics 2010-09-17 S. Garaj , W. Hubbard , A. Reina , J. Kong , D. Branton , J. A. Golovchenko

Angstrom confined solvents in two-dimensional laminates travel through interlayer spacings, gaps between adjacent sheets, and via in plane pores. Among these, experimental access to investigate the mass transport through in plane pores is…

We combine quantum-chemical calculations and molecular dynamics simulations to consider aqueous ion flow across non-axisymmetric nanopores in monolayer graphene and MoS$_2$. When the pore-containing membrane is subject to uniaxial tensile…

Applied Physics · Physics 2020-04-30 A. Smolyanitsky , A. Fang , A. F. Kazakov , E. Paulechka

Ionic transport in nanopores or nanochannels is key to many cellular processes and is now being explored as a method for DNA/polymer sequencing and detection. Although apparently simple in its scope, the study of ionic dynamics in confined…

Mesoscale and Nanoscale Physics · Physics 2013-06-13 Andrew Meyertholen , Massimiliano Di Ventra

Ion transport through nanopores permeates through many areas of science and technology, from cell behavior to sensing and separation to catalysis and batteries. Two-dimensional materials, such as graphene, molybdenum disulfide (MoS$_2$),…

Mesoscale and Nanoscale Physics · Physics 2019-07-19 Subin Sahu , Michael Zwolak

The permeation, rejection, and transport of electrolytes in water-filled nanopores are critical to ion current gating and desalinalion processes in synthetic porous membranes and the functions of biological ion channels. Mile the effects of…

Statistical Mechanics · Physics 2008-04-29 Kevin Leung

Ionic transport in nanopores is a fundamentally and technologically important problem in view of its occurrence in biological processes and its impact on novel DNA sequencing applications. Using microscopic calculations, here we show that…

Soft Condensed Matter · Physics 2009-09-26 Michael Zwolak , Johan Lagerqvist , Massimiliano Di Ventra

With controlled ionic current rectification (ICR) achieved through a strategically designed non-uniform surface charge distribution, short unipolar nanopores exhibit promising applications in nanofluidic sensors, ionic circuits, and ion…

Chemical Physics · Physics 2025-12-08 Hongwen Zhang , Long Ma , Di Liu , Tianyi Sui , Zuzanna S. Siwy , Yinghua Qiu

The distribution of ions and their impact on the structure of electrolyte interfaces plays an important role in many applications. Interestingly, recent experimental studies have suggested the preferential accumulation of $SO_4^{2-}$ ions…

Chemical Physics · Physics 2026-05-11 Ademola Soyemi , Tibor Szilvasi

The ability of semipermeable membranes to selectively impede the transport of undesirable solutes is key to many applications. Yet, obtaining a systematic understanding of how membrane structure affects selectivity remains elusive due to…

Soft Condensed Matter · Physics 2020-01-03 Hessam Malmir , Razi Epsztein , Menachem Elimelech , Amir Haji-Akbari

We employ molecular dynamics simulations to investigate ion and water transport driven by an electric field through quasi-two-dimensional nanoslits with a tapered geometry. Despite the absence of surface charge on the channel walls and the…

Soft Condensed Matter · Physics 2025-09-29 Tim Veenstra , Gerardo Campos-Villalobos , Giuliana Giunta , René van Roij , Marjolein Dijkstra