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In the age of big data and interpretable machine learning, approaches need to work at scale and at the same time allow for a clear mathematical understanding of the method's inner workings. While there exist inherently interpretable…

Computation · Statistics 2023-02-02 David Rügamer

Spatial omics has transformed our understanding of tissue architecture by preserving spatial context of gene expression patterns. Simultaneously, advances in imaging AI have enabled extraction of morphological features describing the…

Computer Vision and Pattern Recognition · Computer Science 2024-08-02 Eduard Chelebian , Christophe Avenel , Carolina Wählby

We introduce a Gibbs Markov random field for spatial data on Cartesian grids which is based on the generalized planar rotator (GPR) model. The GPR model generalizes the recently proposed modified planar rotator (MPR) model by including in…

Methodology · Statistics 2023-02-15 Milan Žukovič , Dionissios T. Hristopulos

Partially linear additive models generalize linear ones since they model the relation between a response variable and covariates by assuming that some covariates have a linear relation with the response but each of the others enter through…

Methodology · Statistics 2023-08-08 Graciela Boente , Alejandra Mercedes Martinez

Unmeasured, spatially-structured factors can confound associations between spatial environmental exposures and health outcomes. Adding flexible splines to a regression model is a simple approach for spatial confounding adjustment, but the…

Applications · Statistics 2020-06-22 Joshua P. Keller , Adam A. Szpiro

This review article focuses on regularised estimation procedures applicable to geostatistical and spatial econometric models. These methods are particularly relevant in the case of big geospatial data for dimensionality reduction or model…

Methodology · Statistics 2026-04-30 Philipp Otto , Alessandro Fassò , Paolo Maranzano

Compositional observations are an increasingly prevalent data source in spatial statistics. Analysis of such data is typically done on log-ratio transformations or via Dirichlet regression. However, these approaches often make unnecessarily…

Methodology · Statistics 2025-05-27 Michael R. Schwob , Mevin B. Hooten , Nicholas M. Calzada , Timothy H. Keitt

This paper deals with variable selection in multivariate linear regression model when the data are observations on a spatial domain being a grid of sites in $\mathbb{Z}^d$ with $d\geqslant 2$. We use a criterion that allows to characterize…

Statistics Theory · Mathematics 2023-05-23 Jean Roland Ebende Penda , Stéphane Bouka , Guy Martial Nkiet

Spatial environmental variation can either amplify or suppress the fixation of beneficial mutants in structured populations, yet the interplay of ecological factors and spatial structure in determining which outcome occurs remains…

Populations and Evolution · Quantitative Biology 2026-05-07 Hossein Nemati , Kamran Kaveh , Jakub Svoboda , Mohammad Reza Ejtehadi , Krishnendu Chatterjee

Single-cell RNA-sequencing technologies may provide valuable insights to the understanding of the composition of different cell types and their functions within a tissue. Recent technologies such as spatial transcriptomics, enable the…

Applications · Statistics 2023-05-16 Arhit Chakrabarti , Yang Ni , Bani K. Mallick

This paper proposes a probabilistic model of subspaces based on the probabilistic principal component analysis (PCA). Given a sample of vectors in the embedding space -- commonly known as a snapshot matrix -- this method uses quantities…

Computational Engineering, Finance, and Science · Computer Science 2025-10-07 Akash Yadav , Ruda Zhang

This paper considers some designs for sampling and interventions in dynamic networks and spatial temporal settings. The sample spreads through the population largely by tracing network links, although random sampling or spatial designs may…

Methodology · Statistics 2013-06-05 Steven K. Thompson

Deep learning methods achieve remarkable predictive performance in modeling complex, large-scale data. However, assessing the quality of derived models has become increasingly challenging, as more classical statistical assumptions may no…

Machine Learning · Statistics 2026-03-02 Daniele Zambon , Cesare Alippi

Spatial confounding between the spatial random effects and fixed effects covariates has been recently discovered and showed that it may bring misleading interpretation to the model results. Solutions to alleviate this problem are based on…

Methodology · Statistics 2016-05-17 Marcos O. Prates , Erica C. Rodrigues , Renato M. Assunção

Spatial statistics is concerned with the analysis of data that have spatial locations associated with them, and those locations are used to model statistical dependence between the data. The spatial data are treated as a single realisation…

Methodology · Statistics 2022-02-09 Noel Cressie , Matthew Sainsbury-Dale , Andrew Zammit-Mangion

We consider spatially dependent functional data collected under a geostatistics setting, where locations are sampled from a spatial point process. The functional response is the sum of a spatially dependent functional effect and a spatially…

Methodology · Statistics 2021-06-18 Haozhe Zhang , Yehua Li

We study settings where gradient penalties are used alongside risk minimization with the goal of obtaining predictors satisfying different notions of monotonicity. Specifically, we present two sets of contributions. In the first part of the…

Machine Learning · Computer Science 2022-05-18 Joao Monteiro , Mohamed Osama Ahmed , Hossein Hajimirsadeghi , Greg Mori

In structured additive distributional regression, the conditional distribution of the response variables given the covariate information and the vector of model parameters is modelled using a P-parametric probability density function where…

Computation · Statistics 2025-02-06 Gianmarco Callegher , Thomas Kneib , Johannes Söding , Paul Wiemann

Spatial Transcriptomics (ST) profiles thousands of gene expression values at discrete spots with precise coordinates on tissue sections, preserving spatial context essential for clinical and pathological studies. With rising sequencing…

Computer Vision and Pattern Recognition · Computer Science 2026-03-24 Yishun Zhu , Jiaxin Qi , Jian Wang , Yuhua Zheng , Jianqiang Huang

Model-agnostic tools for interpreting machine-learning models struggle to summarize the joint effects of strongly dependent features in high-dimensional feature spaces, which play an important role in pattern recognition, for example in…

Machine Learning · Computer Science 2023-06-01 Alexander Brenning