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To provide a phenomenological theory for the various interesting transitions in restructuring networks we employ a statistical mechanical approach with detailed balance satisfied for the transitions between topological states. This enables…

Statistical Mechanics · Physics 2007-05-23 Imre Derenyi , Illes Farkas , Gergely Palla , Tamas Vicsek

Topological landscape is introduced for networks with functions defined on the nodes. By extending the notion of gradient flows to the network setting, critical nodes of different indices are defined. This leads to a concise and…

Methodology · Statistics 2012-05-01 E. Weinan , Jianfeng Lu , Yuan Yao

Many biological, technological, and social systems can be effectively described as networks of interacting subsystems. Typically, these networks are not isolated objects, but interact with their environment through both signals and…

Systems and Control · Electrical Eng. & Systems 2026-01-06 Amirhossein Nazerian , Malbor Asllani , Melvyn Tyloo , Wai Lim Ku , Francesco Sorrentino

Key features of biological activity can often be captured by transitions between a finite number of semi-stable states that correspond to behaviors or decisions. We present here a broad class of dynamical systems that are ideal for modeling…

Dynamical Systems · Mathematics 2022-12-14 Megan Morrison , Lai-Sang Young

Models of simple excitable dynamics on graphs are an efficient framework for studying the interplay between network topology and dynamics. This subject is a topic of practical relevance to diverse fields, ranging from neuroscience to…

Neurons and Cognition · Quantitative Biology 2015-01-12 C. Fretter , A. Lesne , C. C. Hilgetag , M. -Th. Hütt

This thesis is a compendium of research which brings together ideas from the fields of Complex Networks and Computational Neuroscience to address two questions regarding neural systems: 1) How the activity of neurons, via synaptic changes,…

Neurons and Cognition · Quantitative Biology 2013-02-19 Samuel Johnson

Nature is full of random networks of complex topology describing such apparently disparate systems as biological, economical or informatical ones. Their most characteristic feature is the apparent scale-free character of interconnections…

Condensed Matter · Physics 2007-05-23 G. Wilk , Z. Wlodarczyk

The relationship between network topology and system dynamics has significant implications for unifying our understanding of the interplay among metabolic, gene-regulatory, and ecosystem network architecures. Here we analyze the stability…

Populations and Evolution · Quantitative Biology 2015-06-17 Cameron Smith , Raymond S. Puzio , Aviv Bergman

We consider a general class of stochastic networks and ask which network nodes need to be controlled, and how, to stabilize and switch between desired metastable (target) states in terms of the first and second statistical moments of the…

Adaptation and Self-Organizing Systems · Physics 2016-07-20 Dmytro Bielievtsov , Josef Ladenbauer , Klaus Obermayer

A plethora of computational models have been developed in recent decades to account for the morphogenesis of complex biological fluid networks, such as capillary beds. Contemporary adaptation models are based on optimization schemes where…

Tissues and Organs · Quantitative Biology 2021-11-16 Felix Kramer , Carl D. Modes

Mathematical models of motility are often based on random-walk descriptions of discrete individuals that can move according to certain rules. It is usually the case that large masses concentrated in small regions of space have a great…

Physics and Society · Physics 2022-11-23 Carles Falcó

Understanding the interactions among nodes in a complex network is of great importance, since they disclose how these nodes are cooperatively supporting the functioning of the network. Scientists have developed numerous methods to uncover…

Physics and Society · Physics 2017-09-13 Chengwei Wang , Celso Grebogi , Murilo S. Baptista

We study the dynamics of epidemic spreading processes aimed at spontaneous dissemination of information updates in populations with complex connectivity patterns. The influence of the topological structure of the network in these processes…

Statistical Mechanics · Physics 2009-11-10 Yamir Moreno , Maziar Nekovee , Alessandro Vespignani

Scale-free and non-computable characteristics of natural networks are found to result from the least-time dispersal of energy. To consider a network as a thermodynamic system is motivated since ultimately everything that exists can be…

General Physics · Physics 2011-06-22 Tuomo Hartonen , Arto Annila

Many active fluid systems encountered in biology are set in total geometric confinement. Cytoplasmic streaming in plant cells is a prominent and ubiquitous example, in which cargo-carrying molecular motors move along polymer filaments and…

Soft Condensed Matter · Physics 2013-01-10 Francis G. Woodhouse , Raymond E. Goldstein

The problem of stochastic advection of passive particles by circulating conserved flows on networks is formulated and investigated. The particles undergo transitions between the nodes with the transition rates determined by the flows…

Statistical Mechanics · Physics 2015-06-18 Shigefumi Hata , Hiroya Nakao , Alexander S. Mikhailov

A cell's behavior is a consequence of the complex interactions between its numerous constituents, such as DNA, RNA, proteins and small molecules. Cells use signaling pathways and regulatory mechanisms to coordinate multiple processes,…

Molecular Networks · Quantitative Biology 2007-09-12 Reka Albert

Topological protection has emerged as an organizing principle for understanding and engineering robust collective behavior in electronic and material systems. Recent work suggests that topology may also play a role in organizing stochastic…

Statistical Mechanics · Physics 2022-06-17 Pankaj Mehta , Jason Rocks

There has been much research on network flows over time due to their important role in real world applications. This has led to many results, but the more challenging continuous time model still lacks some of the key concepts and techniques…

Systems and Control · Computer Science 2014-01-24 Ebrahim Nasrabadi , Ronald Koch

Deciphering the control principles of metabolism and its interaction with other cellular functions is central to biomedicine and biotechnology. Yet, understanding the efficient control of metabolic fluxes remains elusive for large-scale…

Molecular Networks · Quantitative Biology 2015-09-04 Georg Basler , Zoran Nikoloski , Abdelhalim Larhlimi , Albert-László Barabási , Yang-Yu Liu