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Atrial fibrillation (AF) consequences on the heart valve dynamics are usually studied along with a valvular disfunction or disease, since in medical monitoring the two pathologies are often concomitant. Aim of the present work is to study,…

Fluid Dynamics · Physics 2015-10-27 Stefania Scarsoglio , Carlo Camporeale , Andrea Guala , Luca Ridolfi

Atrial fibrillation (AF) is the most common form of arrhythmia with accelerated and irregular heart rate (HR), leading to both heart failure and stroke and being responsible for an increase in cardiovascular morbidity and mortality. In…

Fluid Dynamics · Physics 2018-06-26 Stefania Scarsoglio , Caterina Gallo , Luca Ridolfi

Background. Different mechanisms have been proposed to relate atrial fibrillation (AF) and coronary flow impairment, even in absence of relevant coronary artery disease (CAD). However, the underlying hemodynamics remains unclear. Aim of the…

Medical Physics · Physics 2019-04-17 Stefania Scarsoglio , Caterina Gallo , Andrea Saglietto , Luca Ridolfi , Matteo Anselmino

We analyze left atrium haemodynamics, highlighting differences among healthy individuals and patients affected by atrial fibrillation. The computational study is based on patient-specific geometries of the left atria to simulate blood flow…

Fluid Dynamics · Physics 2022-10-06 Mattia Corti , Alberto Zingaro , Luca Dede' , Alfio Maria Quarteroni

Computer modeling can provide quantitative insight into cardiac fluid dynamics phenomena that are not evident from standard imaging tools. We propose a new approach to modeling left ventricle fluid dynamics based on an image-driven…

Ventricular Fibrillation (VF) is a malignant cardiac arrhythmia and the leading cause of sudden cardiac death, characterized by disorganized, high-frequency ventricular activity that results in the rapid loss of coordinated pump function…

Biological Physics · Physics 2025-11-04 Artemii Remizov , Sergey Lapin

Atrial fibrillation (AF) is considered the most common human arrhythmia. Around 99\% of thrombi in non-valvular AF are formed in the left atrial appendage (LAA). Studies suggest that abnormal LAA haemodynamics and the subsequently stagnated…

Computational fluid dynamics (CFD) studies of left atrial flows have reached a sophisticated level, e.g., revealing plausible relationships between hemodynamics and stresses with atrial fibrillation. However, little focus has been on…

Atrial fibrillation (AF) is associated with cognitive impairment/dementia, independently of clinical cerebrovascular events (stroke/TIA). One of the plausible mechanisms is the occurrence of AF-induced transient critical hemodynamic events;…

Medical Physics · Physics 2019-03-11 Andrea Saglietto , Stefania Scarsoglio , Luca Ridolfi , Fiorenzo Gaita , Matteo Anselmino

Changes in cardiovascular hemodynamics are closely related to the development of aortic regurgitation, a type of valvular heart disease. Metrics derived from blood flows are used to indicate aortic regurgitation onset and evaluate its…

Computer Vision and Pattern Recognition · Computer Science 2022-04-07 Derek Long , Cameron McMurdo , Edward Ferdian , Charlene A. Mauger , David Marlevi , Alistair A. Young , Martyn P. Nash

Introduction: Characteristics of hemodynamics strongly affect the patency of arteriovenous fistula (AVF) in hemodialysis patients. Because of pressure balance changes among arteries after AVF construction, regurgitating flow occurs in some…

Numerical Analysis · Mathematics 2023-08-30 Surabhi Rathore , Hironobu Sugiyama , Hiroshi Suito

Cardiac disease and clinical intervention may both lead to an increased risk for thrombosis events due to modified blood flow in the heart, and thereby a change in the mechanical stimuli of blood cells passing through the chambers of the…

There has recently been growing evidence that atrial fibrillation (AF), the most common cardiac arrhythmia, is independently associated with the risk of dementia. This represents a very recent frontier with high social impact for the number…

The aortic valve is a three-leaflet passive structure that, driven by pressure differences between the left ventricle and the aorta, opens and closes during the heartbeat to ensure the correct stream direction and flow rate. In elderly…

Fluid Dynamics · Physics 2021-03-30 Francesco Viola , Valentina Meschini , Roberto Verzicco

Image-based computational fluid dynamics (CFD) has emerged as a powerful tool to study cardiovascular flows while 2D echocardiography (echo) is the most widely used non-invasive imaging modality for diagnosis of heart disease. Here, echo is…

Cardiovascular diseases (CVDs) are the leading causes of mortality worldwide. The contraction and relaxation of left ventricle (LV) is the main driving force of blood circulation. Altered LV hemodynamics is believed to be associated with…

Medical Physics · Physics 2019-11-04 Fanwei Kong , Christoph Augustin , Kevin Sack , Shawn Shadden

Atrial fibrillation (AF) is the most common arrhythmia affecting millions of people in the Western countries and, due to the widespread impact on the population and its medical relevance, is largely investigated in both clinical and…

Medical Physics · Physics 2014-09-12 Stefania Scarsoglio , Andrea Guala , Carlo Camporeale , Luca Ridolfi

A network-based approach is presented to investigate the cerebrovascular flow patterns during atrial fibrillation (AF) with respect to normal sinus rhythm (NSR). AF, the most common cardiac arrhythmia with faster and irregular beating, has…

Data Analysis, Statistics and Probability · Physics 2017-09-27 Stefania Scarsoglio , Fabio Cazzato , Luca Ridolfi

Background. Despite the routine prescription of rate control therapy for atrial fibrillation (AF), clinical evidence demonstrating a heart rate target is lacking. Aim of the present study was to run a mathematical model simulating AF…

This study investigates the hemodynamic behavior of blood flow in the aortic arch across anemic, diabetic, and healthy conditions using computational fluid dynamics (CFD) simulations with a non-Newtonian Carreau viscosity model. Velocity…

Fluid Dynamics · Physics 2025-06-23 Farzana Akter Tina , Hashnayne Ahmed , Hena Rani Biswas
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