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Transmission electron microscopy (TEM) is a potent technique for the determination of three-dimensional atomic scale structure of samples in structural biology and materials science. In structural biology, three-dimensional structures of…

Super-resolution microscopy, or nanoscopy, enables the use of fluorescent-based molecular localization tools to study molecular structure at the nanoscale level in the intact cell, bridging the mesoscale gap to classical structural biology…

Subcellular Processes · Quantitative Biology 2024-05-28 Ivan R. Nabi , Ben Cardoen , Ismail M. Khater , Guang Gao , Timothy H. Wong , Ghassan Hamarneh

Accurately tracking particles and determining their coordinate along the optical axis is a major challenge in optical microscopy, especially when extremely high precision is needed. In this study, we introduce a deep learning approach using…

Image and Video Processing · Electrical Eng. & Systems 2025-08-05 Andrey Alexandrov , Giovanni Acampora , Giovanni De Lellis , Antonia Di Crescenzo , Chiara Errico , Daria Morozova , Valeri Tioukov , Autilia Vittiello

Image co-segmentation is important for its advantage of alleviating the ill-pose nature of image segmentation through exploring the correlation between related images. Many automatic image co-segmentation algorithms have been developed in…

Computer Vision and Pattern Recognition · Computer Science 2019-11-19 Xiabi Liu , Xin Duan

In general, objects can be distinguished on the basis of their features, such as color or shape. In particular, it is assumed that similarity judgments about such features can be processed independently in different metric spaces. However,…

Machine Learning · Computer Science 2025-02-13 Yoshiyuki Ohmura , Wataru Shimaya , Yasuo Kuniyoshi

This paper addresses the importance of full-image supervision for monocular depth estimation. We propose a semi-supervised architecture, which combines both unsupervised framework of using image consistency and supervised framework of dense…

Computer Vision and Pattern Recognition · Computer Science 2020-01-31 Bei Wang , Jianping An

Inverse scattering problems without the phase information arise in imaging of nanostructures whose sizes are hundreds of nanometers as well as in imaging of biological cells. The governing equation is the 3-d generalized Helmholtz equation…

Analysis of PDEs · Mathematics 2015-10-05 Michael V. Klibanov , Loc H. Nguyen , Kejia Pan

Autonomous methods to align beamlines can decrease the amount of time spent on diagnostics, and also uncover better global optima leading to better beam quality. The alignment of these beamlines is a high-dimensional, expensive-to-sample…

Existing unsupervised image alignment methods exhibit limited accuracy and high computational complexity. To address these challenges, we propose a dense cross-scale image alignment model. It takes into account the correlations between…

Computer Vision and Pattern Recognition · Computer Science 2025-11-13 Jinkun You , Jiaxue Li , Jie Zhang , Yicong Zhou

Image registration, or alignment of two or more images covering the same scenes or objects, is of great interest in many disciplines such as remote sensing, medical imaging, astronomy, and computer vision. In this paper, we introduce a new…

Computer Vision and Pattern Recognition · Computer Science 2013-01-10 Nargess Memarsadeghi , Jacqueline Le Moigne , Peter N. Blake , Peter A. Morey , Wayne B. Landsman , Victor J. Chambers , Samuel H. Moseley

Identifying the chemical structure from a graphical representation, or image, of a molecule is a challenging pattern recognition task that would greatly benefit drug development. Yet, existing methods for chemical structure recognition do…

Computer Vision and Pattern Recognition · Computer Science 2024-04-03 Martijn Oldenhof , Edward De Brouwer , Adam Arany , Yves Moreau

Nuclear magnetic resonance (NMR) spectroscopy is one of the leading techniques for protein studies. The method features a number of properties, allowing to explain macromolecular interactions mechanistically and resolve structures with…

Quantitative Methods · Quantitative Biology 2018-08-03 Piotr Klukowski , Adam Gonczarek

Scanning tunnelling microscopy (STM) is a powerful technique for imaging surfaces with atomic resolution, providing insight into physical and chemical processes at the level of single atoms and molecules. A regular task of STM image…

Nanoelectromechanical Systems (NEMS) have emerged as a promising technology for performing the mass spectrometry of large biomolecules and nanoparticles. As nanoscale objects land on NEMS sensor one by one, they induce resolvable shifts in…

Mesoscale and Nanoscale Physics · Physics 2019-07-24 Mert Yuksel , Ezgi Orhan , Cenk Yanik , Atakan B. Ari , Alper Demir , M. Selim Hanay

Low energy ion-beam sputtering of GaSb results in self-organized nanostructures, with the potential of structuring large surface areas. Characterisation of such nanostructures by optical methods is studied and compared to direct (local)…

Instance segmentation in electron microscopy (EM) volumes is tough due to complex shapes and sparse annotations. Self-supervised learning helps but still struggles with intricate visual patterns in EM. To address this, we propose a…

Computer Vision and Pattern Recognition · Computer Science 2023-09-06 Yinda Chen , Wei Huang , Xiaoyu Liu , Shiyu Deng , Qi Chen , Zhiwei Xiong

We propose a semantic similarity metric for image registration. Existing metrics like euclidean distance or normalized cross-correlation focus on aligning intensity values, giving difficulties with low intensity contrast or noise. Our…

Computer Vision and Pattern Recognition · Computer Science 2020-11-12 Steffen Czolbe , Oswin Krause , Aasa Feragen

Homography estimation is a basic image alignment method in many applications. It is usually conducted by extracting and matching sparse feature points, which are error-prone in low-light and low-texture images. On the other hand, previous…

Computer Vision and Pattern Recognition · Computer Science 2020-07-21 Jirong Zhang , Chuan Wang , Shuaicheng Liu , Lanpeng Jia , Nianjin Ye , Jue Wang , Ji Zhou , Jian Sun

Depth estimation is a crucial step for image-guided intervention in robotic surgery and laparoscopic imaging system. Since per-pixel depth ground truth is difficult to acquire for laparoscopic image data, it is rarely possible to apply…

Computer Vision and Pattern Recognition · Computer Science 2023-06-22 Baoru Huang , Jian-Qing Zheng , Anh Nguyen , Chi Xu , Ioannis Gkouzionis , Kunal Vyas , David Tuch , Stamatia Giannarou , Daniel S. Elson

Scanning transmission electron microscopy (STEM) has become a cornerstone instrument for semiconductor materials metrology, enabling nanoscale analysis of complex multilayer structures that define device performance. Developing effective…