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Motivation: Millions of genes in the modern species belong to only thousands of `gene families'. A gene family includes instances of the same gene in different species (orthologs) and duplicate genes in the same species (paralogs). Genes…

Populations and Evolution · Quantitative Biology 2012-05-04 Yu Zheng , Taoyang Wu , Louxin Zhang

Phylogenetic networks are a type of leaf-labelled, acyclic, directed graph used by biologists to represent the evolutionary history of species whose past includes reticulation events. A phylogenetic network is tree-child if each non-leaf…

Combinatorics · Mathematics 2017-11-27 Magnus Bordewich , Katharina T Huber , Vincent Moulton , Charles Semple

In molecular phylogeny, relationships among organisms are reconstructed using DNA or protein sequences and are displayed as trees. A linear increase in the number of sequences results in an exponential increase of possible trees. Thus,…

Genomics · Quantitative Biology 2007-05-23 Kerstin Hoef-Emden

Tree containment problem is a fundamental problem in phylogenetic study, as it is used to verify a network model. It asks whether a given network contain a subtree that resembles a binary tree. The problem is NP-complete in general, even in…

Populations and Evolution · Quantitative Biology 2017-02-15 Andreas Gunawan

Phylogenetic networks provide a means of describing the evolutionary history of sets of species believed to have undergone hybridization or gene flow during their evolution. The mutation process for a set of such species can be modeled as a…

Populations and Evolution · Quantitative Biology 2022-11-23 Travis Barton , Elizabeth Gross , Colby Long , Joseph Rusinko

Recently, much attention has been given to understanding recombination events along a chromosome in a variety of field. For instance, many population genetics problems are limited by the inaccuracy of inferred evolutionary histories of…

Quantitative Methods · Quantitative Biology 2017-10-31 Jacqueline Kane , Joseph Rusinko , Katherine Thompson

Phylogenetic networks provide a way to describe and visualize evolutionary histories that have undergone so-called reticulate evolutionary events such as recombination, hybridization or horizontal gene transfer. The level k of a network…

Populations and Evolution · Quantitative Biology 2008-07-21 Leo van Iersel , Steven Kelk , Matthias Mnich

A phylogenetic tree is an important way in Bioinformatics to find the evolutionary relationship among biological species. In this research, a proposed model is described for the estimation of a phylogenetic tree for a given set of data. To…

Populations and Evolution · Quantitative Biology 2025-09-03 S M Rafiuddin

Phylogenetic tree shapes capture fundamental signatures of evolution. We consider ``ranked'' tree shapes, which are equipped with a total order on the internal nodes compatible with the tree graph. Recent work has established an elegant…

Populations and Evolution · Quantitative Biology 2026-03-10 Chris Jennings-Shaffer , Ziyue , Chen , Julia A Palacios , Frederick A Matsen

Phylogenetic trees (i.e. evolutionary trees, additive trees or X-trees) play a key role in the processes of modeling and representing species evolution. Genome evolution of a given group of species is usually modeled by a species…

Populations and Evolution · Quantitative Biology 2023-01-03 Vladimir Makarenkov , Gayane S. Barseghyan , Nadia Tahiri

Rooted phylogenetic networks are used by biologists to infer and represent complex evolutionary relationships between species that cannot be accurately explained by a phylogenetic tree. Tree-child networks are a particular class of rooted…

Combinatorics · Mathematics 2024-09-02 Janosch Döcker , Simone Linz

Phylogenetic networks generalize phylogenetic trees by representing reticulate evolution. Tree-based networks and their support trees have been extensively studied, but not all networks are tree-based. To measure how far such networks are…

Populations and Evolution · Quantitative Biology 2026-05-27 Takatora Suzuki

Phylogenetic (evolutionary) trees and networks are leaf-labeled graphs that are widely used to represent the evolutionary relationships between entities such as species, languages, cancer cells, and viruses. To reconstruct and analyze…

Data Structures and Algorithms · Computer Science 2023-08-21 Michael J. Dinneen , Pankaj S. Ghodla , Simone Linz

Sequence comparison and alignment has had an enormous impact on our understanding of evolution, biology, and disease. Comparison and alignment of biological networks will likely have a similar impact. Existing network alignments use…

Molecular Networks · Quantitative Biology 2009-10-08 Oleksii Kuchaiev , Tijana Milenkovic , Vesna Memisevic , Wayne Hayes , Natasa Przulj

Tree-based networks are a class of phylogenetic networks that attempt to formally capture what is meant by "tree-like" evolution. A given non-tree-based phylogenetic network, however, might appear to be very close to being tree-based, or…

Populations and Evolution · Quantitative Biology 2020-01-17 Mareike Fischer , Andrew Francis

Attempting to recognize a tree inside a phylogenetic network is a fundamental undertaking in evolutionary analysis. In the last few years, therefore, tree-based phylogenetic networks, which are defined by a spanning tree called a…

Combinatorics · Mathematics 2020-09-29 Momoko Hayamizu

Reconstructing the tree of life from molecular sequences is a fundamental problem in computational biology. Modern data sets often contain a large number of genes, which can complicate the reconstruction problem due to the fact that…

Probability · Mathematics 2017-07-21 Constantinos Daskalakis , Sebastien Roch

Phylogenetic trees are a central tool in understanding evolution. They are typically inferred from sequence data, and capture evolutionary relationships through time. It is essential to be able to compare trees from different data sources…

Populations and Evolution · Quantitative Biology 2017-10-31 Michelle Kendall , Caroline Colijn

An important and well-studied problem in phylogenetics is to compute a \emph{consensus tree} so as to summarize the common features within a collection of rooted phylogenetic trees, all whose leaf-sets are bijectively labeled by the same…

Populations and Evolution · Quantitative Biology 2021-07-22 Katharina T. Huber , Vincent Moulton , Andreas Spillner

Combining a set of phylogenetic trees into a single phylogenetic network that explains all of them is a fundamental challenge in evolutionary studies. Existing methods are computationally expensive and can either handle only small numbers…

Populations and Evolution · Quantitative Biology 2023-04-07 Giulia Bernardini , Leo van Iersel , Esther Julien , Leen Stougie
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