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Standard optimal control methods perform optimization in the time domain. However, many experimental settings demand the expression of the control signal as a superposition of given waveforms, a case that cannot easily be accommodated using…

Optimization and Control · Mathematics 2015-06-22 Selina Meister , Jürgen T. Stockburger , Rebecca Schmidt , Joachim Ankerhold

Spiking neuronal networks are usually simulated with three main simulation schemes: the classical time-driven and event-driven schemes, and the more recent hybrid scheme. All three schemes evolve the state of a neuron through a series of…

Neurons and Cognition · Quantitative Biology 2018-01-24 Jeyashree Krishnan , PierGianLuca Porta Mana , Moritz Helias , Markus Diesmann , Edoardo Di Napoli

Optimal control is a central problem in quantum thermodynamics. When minimizing dissipated work and work fluctuations defined via the two-point measurement scheme in open quantum systems, existing approaches largely focus on the rapid- and…

Quantum Physics · Physics 2026-04-08 Yuki Kurokawa , Yoshihiko Hasegawa

Reaction-diffusion systems offer a powerful framework for understanding self-organized patterns in biological systems, yet controlling these patterns remains a significant challenge. As a consequence, we present a rigorous framework of…

Optimization and Control · Mathematics 2026-04-13 Mohamed Amine Ouchdiri , Hamza Faquir , Saad Benjelloun , Mohamed Adlene Maghenem , Irene Otero-Muras , Adnane Saoud

A complex interplay of single-neuron properties and the recurrent network structure shapes the activity of cortical neurons. The single-neuron activity statistics differ in general from the respective population statistics, including…

Neurons and Cognition · Quantitative Biology 2021-11-02 Alexander van Meegen , Sacha J. van Albada

We study the optimal control problem for a control-affine system, where we want to minimize the $L^1$ norm of the control. First, we show how Pontryagin Maximum Principle (PMP) applies to this problem and we divide the extremal trajectories…

Optimization and Control · Mathematics 2025-12-02 Andrei Agrachev , Ivan Beschastnyi , Michele Motta

In this article we study the minimal time for the exact controllability of one-dimensional first-order linear hyperbolic systems when all the controls are acting on the same side of the boundary. We establish an explicit and easy-to-compute…

Optimization and Control · Mathematics 2019-02-22 Long Hu , Guillaume Olive

This paper treats an optimal scheduling problem of control nodes in networked systems. We newly introduce both the L0 and l0 constraints on control inputs to extract a time-varying small number of effective control nodes. As the cost…

Optimization and Control · Mathematics 2021-08-31 Takuya Ikeda , Kazunori Sakurama , Kenji Kashima

This paper is concerned with impulse approximate controllability for stochastic evolution equations with impulse controls. As direct applications, we formulate captivating minimal norm and time optimal control problems; The minimal norm…

Optimization and Control · Mathematics 2024-01-09 Yuanhang Liu

We investigate several control strategies for the transport of an excitation along a spin chain. We demonstrate that fast, high fidelity transport can be achieved using protocols designed with differentiable programming. Building on this,…

Quantum Physics · Physics 2022-11-30 Luuk Coopmans , Steve Campbell , Gabriele De Chiara , Anthony Kiely

The way the brain selects and controls actions is still widely debated. Mainstream approaches based on Optimal Control focus on stimulus-response mappings that optimize cost functions. Ideomotor theory and cybernetics propose a different…

Precise timing of spikes and temporal locking are key elements of neural computation. Here we demonstrate how even strongly heterogeneous, deterministic neural networks with delayed interactions and complex topology can exhibit periodic…

Neurons and Cognition · Quantitative Biology 2009-11-13 Raoul-Martin Memmesheimer , Marc Timme

Network control theory (NCT) has recently been utilized in neuroscience to facilitate our understanding of brain stimulation effects. A particularly useful branch of NCT is optimal control, which focuses on applying theoretical and…

Other Quantitative Biology · Quantitative Biology 2025-01-17 Kangli Dong , Siya Chen , Ying Dan , Lu Zhang , Xinyi Li , Wei Liang , Yue Zhao , Yu Sun

Research has characterized the various forms cognitive control can take, including enhancement of goal-relevant information, suppression of goal-irrelevant information, and overall inhibition of potential responses, and has identified…

Neurons and Cognition · Quantitative Biology 2022-01-04 Harrison Ritz , Xiamin Leng , Amitai Shenhav

We investigate the time-optimal control problem in SIR (Susceptible-Infected-Recovered) epidemic models, focusing on different control policies: vaccination, isolation, culling, and reduction of transmission. Applying the Pontryagin's…

Optimization and Control · Mathematics 2017-06-15 Luca Bolzoni , Elena Bonacini , Cinzia Soresina , Maria Groppi

In this work, we investigate the optimal control problem for continuous-time Markov decision processes with the random impact of the environment. We provide conditions to show the existence of optimal controls under finite-horizon criteria.…

Optimization and Control · Mathematics 2020-06-23 Jinghai Shao , Kun Zhao

Characterising the representation of sensory stimuli in the brain is a fundamental scientific endeavor, which can illuminate principles of information coding. Most characterizations reduce the dimensionality of neural data by converting…

Neurons and Cognition · Quantitative Biology 2024-01-23 James B Isbister

A learning approach for optimal feedback gains for nonlinear continuous time control systems is proposed and analysed. The goal is to establish a rigorous framework for computing approximating optimal feedback gains using neural networks.…

Optimization and Control · Mathematics 2020-08-27 Karl Kunisch , Daniel Walter

This paper considers the problem of designing time-dependent, real-time control policies for controllable nonlinear diffusion processes, with the goal of obtaining maximally-informative observations about parameters of interest. More…

Methodology · Statistics 2014-10-16 Giles Hooker , Kevin K. Lin , Bruce Rogers

We study the optimal control of the mean and variance of the network state vector. We develop an algorithm that uses projected gradient descent to optimize the control input placement, subject to constraints on the state that must be…

Optimization and Control · Mathematics 2024-04-16 Philip Solimine , Anke Meyer-Baese
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