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In epidemiology, some have argued that multiple comparison corrections are not necessary as there is rarely interest in the universal null hypothesis. From a parameter estimation perspective, epidemiologists may still be interested in…

Confidence sets play a fundamental role in statistical inference. In this paper, we consider confidence intervals for high dimensional linear regression with random design. We first establish the convergence rates of the minimax expected…

Statistics Theory · Mathematics 2015-11-30 T. Tony Cai , Zijian Guo

National statistical institutes in many countries are now mandated to produce reliable statistics for important variables such as population, income, unemployment, health outcomes, etc. for small areas, defined by geography and/or…

Methodology · Statistics 2018-10-29 Adrijo Chakraborty , Gauri Sankar Datta , Abhyuday Mandal

Bayesian inference is widely used in many different fields to test hypotheses against observations. In most such applications, an assumption is made of precise input values to produce a precise output value. However, this is unrealistic for…

Artificial Intelligence · Computer Science 2025-09-12 John T. Rickard , William A. Dembski , James Rickards

Empirical likelihood is a popular nonparametric or semi-parametric statistical method with many nice statistical properties. Yet when the sample size is small, or the dimension of the accompanying estimating function is high, the…

Statistics Theory · Mathematics 2010-10-05 Yukun Liu , Jiahua Chen

We consider the nonparametric multivariate isotonic regression problem, where the regression function is assumed to be nondecreasing with respect to each predictor. Our goal is to construct a Bayesian credible interval for the function…

Statistics Theory · Mathematics 2022-11-24 Kang Wang , Subhashis Ghosal

We develop scalable methods for producing conformal Bayesian predictive intervals with finite sample calibration guarantees. Bayesian posterior predictive distributions, $p(y \mid x)$, characterize subjective beliefs on outcomes of…

Methodology · Statistics 2021-06-15 Edwin Fong , Chris Holmes

Small area estimation (SAE) improves estimates for local communities or groups, such as counties, neighborhoods, or demographic subgroups, when data are insufficient for each area. This is important for targeting local resources and…

Methodology · Statistics 2026-01-28 Rayleigh Lei , Yajuan Si

In the present paper, we derive lower bounds for the risk of the nonparametric empirical Bayes estimators. In order to attain the optimal convergence rate, we propose generalization of the linear empirical Bayes estimation method which…

Statistics Theory · Mathematics 2013-06-12 Rida Benhaddou , Marianna Pensky

This paper studies the construction of adaptive confidence intervals under Huber's contamination model when the contamination proportion is unknown. For the robust confidence interval of a Gaussian mean, we show that the optimal length of…

Statistics Theory · Mathematics 2025-06-05 Yuetian Luo , Chao Gao

This paper revisits the classical problem of interval estimation of a binomial proportion under Huber contamination. Our main result derives the rate of optimal interval length when the contamination proportion is unknown under a local…

Statistics Theory · Mathematics 2026-01-13 Minjun Cho , Yuetian Luo , Chao Gao

We consider clinical trials in which an experimental treatment is compared with a control in pre-specified patient subpopulations. In such settings, adaptive enrichment designs allow the enrolled population to be modified at an interim…

Methodology · Statistics 2026-03-17 Enyu Li , Nigel Stallard , Ekkehard Glimm , Dominic Magirr , Peter K. Kimani

Bayes factors for composite hypotheses have difficulty in encoding vague prior knowledge, as improper priors cannot be used and objective priors may be subjectively unreasonable. To address these issues I revisit the posterior Bayes factor,…

Methodology · Statistics 2024-02-29 Frank Dudbridge

We study empirical Bayes estimation in high-dimensional linear regression. To facilitate computationally efficient estimation of the underlying prior, we adopt a variational empirical Bayes approach, introduced originally in Carbonetto and…

Statistics Theory · Mathematics 2023-10-27 Sumit Mukherjee , Bodhisattva Sen , Subhabrata Sen

Using normal approximation (NA) to construct a kernel-smoother-based confidence interval faces a fundamental challenge: the normalization makes a small estimation bias become a non-negligible inferential bias. This paper takes a different…

Statistics Theory · Mathematics 2026-05-28 Zihao Yuan , Sven Klaassen

Observational healthcare data offer the potential to estimate causal effects of medical products on a large scale. However, the confidence intervals and p-values produced by observational studies only account for random error and fail to…

Applications · Statistics 2024-05-02 Jami J. Mulgrave , David Madigan , George Hripcsak

We discuss the use of empirical Bayes for data integration, in the sense of transfer learning. Our main interest is in settings where one wishes to learn structure (e.g. feature selection) and one only has access to incomplete data from…

Methodology · Statistics 2026-02-06 Paul Rognon-Vael , David Rossell

The Frequentist, Assisted by Bayes (FAB) framework constructs confidence regions that leverage prior information about parameter values. FAB confidence regions (FAB-CRs) have smaller volume for values of the parameter that are likely under…

Methodology · Statistics 2025-07-01 Stefano Cortinovis , François Caron

Two-stage hierarchical models have been widely used in small area estimation to produce indirect estimates of areal means. When the areas are treated exchangeably and the model parameters are assumed to be the same over all areas, we might…

Methodology · Statistics 2020-01-10 Shonosuke Sugasawa , Yuki Kawakubo , Kota Ogasawara

We construct honest confidence regions for a Hilbert space-valued parameter in various statistical models. The confidence sets can be centered at arbitrary adaptive estimators, and have diameter which adapts optimally to a given selection…

Statistics Theory · Mathematics 2007-06-13 James Robins , Aad van der Vaart