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The idea to estimate the statistical interdependence among (interacting) brain regions has motivated numerous researchers to investigate how the resulting connectivity patterns and networks may organize themselves under any conceivable…

Neurons and Cognition · Quantitative Biology 2021-02-03 Matteo Fraschini , Simone Maurizio La Cava , Luca Didaci , Luigi Barberini

Identifying causal relationships among distinct brain areas, known as effective connectivity, holds key insights into the brain's information processing and cognitive functions. Electroencephalogram (EEG) signals exhibit intricate dynamics…

Signal Processing · Electrical Eng. & Systems 2023-07-20 Peizhen Yang , Xinke Shen , Zongsheng Li , Zixiang Luo , Kexin Lou , Quanying Liu

Human brain development is a complex and dynamic process that is affected by several factors such as genetics, sex hormones, and environmental changes. A number of recent studies on brain development have examined functional connectivity…

Computer Vision and Pattern Recognition · Computer Science 2020-01-29 Peyman Hosseinzadeh Kassani , Li Xiao , Gemeng Zhang , Julia M. Stephen , Tony W. Wilson , Vince D. Calhoun , Yu Ping Wang

The human brain is a large-scale network which function depends on dynamic interactions between spatially-distributed regions. In the rapidly-evolving field of network neuroscience, two yet unresolved challenges are potential breakthroughs.…

Neurons and Cognition · Quantitative Biology 2018-01-09 M. Hassan , F. Wendling

An important field of research in functional neuroimaging is the discovery of integrated, distributed brain systems and networks, whose different regions need to work in unison for normal functioning. The EEG is a non-invasive technique…

A novel approach is developed for discovering directed connectivity between specified pairs of nodes in a high-dimensional network (HDN) of brain signals. To accurately identify causal connectivity for such specified objectives, it is…

Applications · Statistics 2025-05-06 Sipan Aslan , Hernando Ombao

MEG and EEG are noninvasive functional neuroimaging techniques that provide recordings of brain activity with high temporal resolution, and thus provide a unique window to study fast time-scale neural dynamics in humans. However, the…

Applications · Statistics 2015-11-13 Camilo Lamus , Matti S. Hamalainen , Emery N. Brown , Patrick L. Purdon

Contemporary neuroimaging methods can shed light on the basis of human neural and cognitive specializations, with important implications for neuroscience and medicine. Different MRI acquisitions provide different brain networks at the…

Neurons and Cognition · Quantitative Biology 2016-02-23 C. Alonso-Montes , I. Diez , L. Remaki , I. Escudero , B. Mateos , Y. Rosseel , D. Marinazzo , S. Stramaglia , J. Cortes

This paper indicates causality as the tool that unifies the analysis of both activations and connectivity of brain areas, obtained with fMRI data. Causality analysis is commonly applied to study connectivity, so this work focuses on…

Methodology · Statistics 2011-02-25 Nevio Dubbini

As neuroscientists we want to understand how causal interactions or mechanisms within the brain give rise to perception, cognition, and behavior. It is typical to estimate interaction effects from measured activity using statistical…

Neurons and Cognition · Quantitative Biology 2020-10-26 David Marc Anton Mehler , Konrad Paul Kording

This paper is motivated by studies in neuroscience experiments to understand interactions between nodes in a brain network using different types of data modalities that capture different distinct facets of brain activity. To assess…

Brain connectivity can be estimated through a wide number of analyses applied to electroencephalographic (EEG) data. However, substantial heterogeneity in the implementation of connectivity methods exist. Heterogeneity in conceptualization…

Neurons and Cognition · Quantitative Biology 2021-09-01 Aleksandra Miljevic , Neil W. Bailey , Fidel Vila-Rodriguez , Sally E. Herring , Paul B. Fitzgerald

In this work we use numerical simulation to investigate how the temporal length of the data affects the reliability of the estimates of brain connectivity from EEG time--series. We assume that the neural sources follow a stable MultiVariate…

Quantitative Methods · Quantitative Biology 2017-11-10 Sara Sommariva , Alberto Sorrentino , Michele Piana , Vittorio Pizzella , Laura Marzetti

In this paper, we address the the major hurdle of high dimensionality in EEG analysis by extracting the optimal lower dimensional representations. Using our approach, connectivity between regions in a high-dimensional brain network is…

Applications · Statistics 2016-10-26 Yuxiao Wang , Chee-Ming Ting , Hernando Ombao

We propose a novel technique to assess functional brain connectivity in EEG/MEG signals. Our method, called Sparsely-Connected Sources Analysis (SCSA), can overcome the problem of volume conduction by modeling neural data innovatively with…

Methodology · Statistics 2010-08-05 Stefan Haufe , Ryota Tomioka , Guido Nolte , Klaus-Robert Mueller , Motoaki Kawanabe

Separation of the sources and analysis of their connectivity have been an important topic in EEG/MEG analysis. To solve this problem in an automatic manner, we propose a two-layer model, in which the sources are conditionally uncorrelated…

Machine Learning · Computer Science 2012-03-19 Kun Zhang , Aapo Hyvarinen

Neural processes in the brain operate at a range of temporal scales. Granger causality, the most widely-used neuroscientific tool for inference of directed functional connectivity from neurophsyiological data, is traditionally deployed in…

Applications · Statistics 2019-07-17 Lionel Barnett , Anil K. Seth

Extracting causal connections can advance interpretable AI and machine learning. Granger causality (GC) is a robust statistical method for estimating directed influences (DC) between signals. While GC has been widely applied to analysing…

Neurons and Cognition · Quantitative Biology 2024-08-06 Abdoreza Asadpour , KongFatt Wong-Lin

High temporal resolution measurements of human brain activity can be performed by recording the electric potentials on the scalp surface (electroencephalography, EEG), or by recording the magnetic fields near the surface of the head…

Data Analysis, Statistics and Probability · Physics 2015-01-22 Kevin H. Knuth

Objective: This study proposes a new parametric TF (time frequency) CGC (conditional Granger causality) method for high precision connectivity analysis over time and frequency in multivariate coupling nonstationary systems, and applies it…

Signal Processing · Electrical Eng. & Systems 2018-10-23 Yang Li , Mengying Lei , Weigang Cui , Yuzhu Guo , Hua-Liang Wei
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