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A desire to achieve large medical imaging datasets keeps increasing as machine learning algorithms, parallel computing, and hardware technology evolve. Accordingly, there is a growing demand in pooling data from multiple clinical and…

Image and Video Processing · Electrical Eng. & Systems 2021-12-06 Yukai Zou , Ikbeom Jang

Estimating sample size and statistical power is an essential part of a good study design. This R package allows users to conduct power analysis based on Monte Carlo simulations in settings in which consideration of the correlations between…

Methodology · Statistics 2024-04-16 Phuc H. Nguyen , Stephanie M. Engel , Amy H. Herring

Quantile-based approaches to the spectral analysis of time series have recently attracted a lot of attention. Despite a growing literature that contains various estimation proposals, no systematic methods for computing the new estimators…

Computation · Statistics 2014-08-29 Tobias Kley

As part of Mathematical Research Data Initiative (MaRDI), we have developed a way to preserve a software package into an easy to deploy and use sandbox environment we call a "runtime", via a program we developed called MaPS : MaRDI…

Mathematical Software · Computer Science 2025-07-04 Aaruni Kaushik

A key tool in the package of software available for the analysis of data from the SPI spectrometer of Integral is the SPIROS system developed at the University of Birmingham. Although intended primarily for the analysis of point sources and…

Astrophysics · Physics 2009-11-10 G. K. Skinner , P. H. Connell

Molecular dynamics (MD) simulation is a powerful tool for studying biomolecular structural changes, molecular recognition, transmembrane transport, and functional mechanisms. However, its practical bottleneck lies not only in software…

Quantitative Methods · Quantitative Biology 2026-04-22 Zhenyu Ma , Chunyi Yang , Yuyang Song , Jingyi Zhu , Letian Yang , Limei Xu , Min Xiao , Xukai Jiang

Simulations with high accuracy are an essential part of scientific research to accelerate the innovation process. They are especially useful for finding novel approaches or optimizing existing methods. Today, powerful software tools are…

Medical Physics · Physics 2022-08-31 Patrick Vogel , Martin A. Rückert , Thomas Kampf , Volker C. Behr

We sought to develop a quantitative tool to quickly determine relative differences in MRI volumes both within and between large MR imaging cohorts (such as available in The Cancer Imaging Archive (TCIA)), in order to help determine the…

Image and Video Processing · Electrical Eng. & Systems 2021-06-09 Amir Reza Sadri , Andrew Janowczyk , Ren Zou , Ruchika Verma , Niha Beig , Jacob Antunes , Anant Madabhushi , Pallavi Tiwari , Satish E. Viswanath

Among the different types of skin cancer, melanoma is considered to be the deadliest and is difficult to treat at advanced stages. Detection of melanoma at earlier stages can lead to reduced mortality rates. Desktop-based computer-aided…

Image and Video Processing · Electrical Eng. & Systems 2022-05-26 Upender Kalwa , Christopher Legner , Taejoon Kong , Santosh Pandey

Liquid Chromatography Mass Spectrometry (LC-MS) is an indispensable analytical technique in proteomics, metabolomics, and other life sciences. While OpenMS provides advanced open-source software for MS data analysis, its complexity can be…

Machine learning (ML) offers a collection of powerful approaches for detecting and modeling associations, often applied to data having a large number of features and/or complex associations. Currently, there are many tools to facilitate…

Radiative transfer is a key component in almost all astrophysical and cosmological simulations. We present Magritte: a modern open-source software library for 3D radiative transfer. It uses a deterministic ray-tracer and formal solver, i.e.…

Instrumentation and Methods for Astrophysics · Physics 2020-01-08 Frederik De Ceuster , Ward Homan , Jeremy Yates , Leen Decin , Peter Boyle , James Hetherington

Two blind source separation methods (Independent Component Analysis and Non-negative Matrix Factorization), developed initially for signal processing in engineering, found recently a number of applications in analysis of large-scale data in…

Quantitative Methods · Quantitative Biology 2015-02-03 Andrei Zinovyev , Ulykbek Kairov , Tatiana Karpenyuk , Erlan Ramanculov

AMDAT (Amorphous Molecular Dynamics Analysis Toolkit) is an open-source C++ toolkit for post-processing molecular dynamics trajectories, focused on high-performance static and dynamic analyses of amorphous, glassy, and polymer materials,…

Materials Science · Physics 2026-02-06 Pierre Kawak , William F. Drayer , David S. Simmons

It is critical to accurately simulate data when employing Monte Carlo techniques and evaluating statistical methodology. Measurements are often correlated and high dimensional in this era of big data, such as data obtained in…

As genomic scale datasets motivate research on species tree inference, simulators of the multispecies coalescent (MSC) process are essential for the testing and evaluation of new inference methods. However, the simulators themselves must be…

Populations and Evolution · Quantitative Biology 2019-08-06 Elizabeth S. Allman , Hector Baños , John A. Rhodes

We present gradiend, an open-source Python package that operationalizes the GRADIEND method for learning feature directions from factual-counterfactual MLM and CLM gradients in language models. The package provides a unified workflow for…

Computation and Language · Computer Science 2026-03-02 Jonathan Drechsel , Steffen Herbold

We develop a Python-based open-source package to analyze the results stemming from ab initio molecular-dynamics simulations of fluids. The package is best suited for applications on natural systems, like silicate and oxide melts,…

We present the W-SLDA Toolkit, a general-purpose software package for simulating ultracold Fermi gases within the framework of density functional theory and its time-dependent extensions. The toolkit enables fully microscopic studies of…

Quantum Gases · Physics 2026-02-10 Gabriel Wlazłowski , Piotr Magierski , Michael McNeil Forbes , Aurel Bulgac

Accurate and efficient detection of ovarian cancer at early stages is critical to ensure proper treatments for patients. Among the first-line modalities investigated in studies of early diagnosis are features distilled from protein mass…

Machine Learning · Computer Science 2022-07-15 Dixon Vimalajeewa , Scott Alan Bruce , Brani Vidakovic
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