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Driven by the need for describing and understanding wave propagation in structural materials and components, several analytical, numerical, and experimental techniques have been developed to obtain dispersion curves. Accurate…

Signal Processing · Electrical Eng. & Systems 2020-02-26 Mohammad I. Albakri , Vijaya V. N. Sriram Malladi , Serkan Gugercin , Pablo A. Tarazaga

This study introduces a novel data-centric approach to improve real-time surgical guidance using fiber-based fluorescence lifetime imaging (FLIm). A key aspect of the methodology is the accurate detection of the aiming beam, which is…

Artificial Intelligence · Computer Science 2024-11-13 Mohamed Abul Hassan , Pu Sun , Xiangnan Zhou , Lisanne Kraft , Kelsey T Hadfield , Katjana Ehrlich , Jinyi Qi , Andrew Birkeland , Laura Marcu

Wavelength stability of free-electron lasers (FELs) is one of the important parameters for various applications. In this paper we describe two different methods to diagnose the wavelength stability of a mid-infrared (MIR) FEL. The first one…

In many industries, including aerospace and defense, waveform analysis is commonly conducted to compute the resonance of physical objects, with the Finite Element Method (FEM) being the standard approach. The Finite Difference Method (FDM)…

Audio and Speech Processing · Electrical Eng. & Systems 2025-07-09 Juliette Florin

In fluorescence diffuse optical tomography (fDOT), the reconstruction of the fluorophore concentration inside the target body is usually carried out using a normalized Born approximation model where the measured fluorescent emission data is…

Computational Physics · Physics 2015-01-05 Meghdoot Mozumder , Tanja Tarvainen , Simon Arridge , Jari P. Kaipio , Cosimo d'Andrea , Ville Kolehmainen

Advanced accelerator-based light sources such as free electron lasers (FEL) accelerate highly relativistic electron beams to generate incredibly short (10s of femtoseconds) coherent flashes of light for dynamic imaging, whose brightness…

Accelerator Physics · Physics 2024-07-19 Alexander Scheinker

The mechanical properties of soft materials can be probed on small length scales by various microrheology methods. A common approach tracks fluctuations of micrometer-sized beads embedded in the medium to be characterized. This approach…

Soft Condensed Matter · Physics 2021-10-13 Kengo Nishi , Fred C. MacKintosh , Christoph F. Schmidt

Using a streak camera, we directly measure time- and space-resolved dynamics of N2+ emission from a self-seeded filament. We observe characteristic signatures of superfluorescence even under ambient conditions and show that the timing of…

Optics · Physics 2020-01-03 Ali Rastegari , Jean-Claude Diels , Lee R. Liu , Ladan Arissian

Light sheet fluorescence microscopy (LSFM) has transformed the way we visualize biological tissues in three dimensions, offering high-resolution imaging while minimizing photo-induced damage to the samples. Recent breakthroughs in…

Optics · Physics 2025-05-27 Alireza Tabatabaei Mashayekh , Jeremy Witzens

Amperometry is a commonly used electrochemical method for studying the process of exocytosis in real-time. Given the high precision of recording that amperometry procedures offer, the volume of data generated can span over several hundreds…

Subcellular Processes · Quantitative Biology 2023-02-07 Jeyashree Krishnan , Zeyu Lian , Pieter E. Oomen , Xiulan He , Soodabeh Majdi , Andreas Schuppert , Andrew Ewing

Imaging flow cytometry shows significant potential for increasing our understanding of heterogeneous and complex life systems and is useful for biomedical applications. Ghost cytometry is a recently proposed approach for directly analyzing…

Optical turbulence modelling and simulation are crucial for developing astronomical ground-based instruments, laser communication, laser metrology, or any application where light propagates through a turbulent medium. In the context of…

Instrumentation and Methods for Astrophysics · Physics 2024-04-05 A. Berdja , M. Hadjara , M. Carbillet , R. L. Bernardi , R. G. Petrov

Interaction-free measurement (IFM) is a promising technique for low-dose detection and imaging, offering the unique advantage of probing an object without absorption of the interrogating photons. We propose an experiment to demonstrate IFM…

Quantum Physics · Physics 2024-07-10 Ron Cohen , Sharon Shwartz , Eliahu Cohen

Fluorescence microscopy has revolutionized biomedical research over the past three decades. Its high molecular specificity and unrivaled single molecule level sensitivity have enabled breakthroughs in a variety of research fields. For in…

Optics · Physics 2012-03-21 Meng Cui , Ke Si , Reto Fiolka

The author discusses the laser interference method to measure the size of small bio-particles: extracellular vesicles (EVs), exosomes and viruses of nanometer scale in flow cytometry. By introducing a new laser configuration in place of…

Instrumentation and Detectors · Physics 2021-05-26 T. Shintake

Chlorophyll fluorescence (CF) is a key indicator to study plant physiology or photosynthesis efficiency. Conventionally, CF is characterized by fluorometers, which only allows ensemble measurement through wide-field detection. For imaging…

Biological Physics · Physics 2016-11-10 Yi-Chin Tseng , Shi-Wei Chu

Spatial Fluorescence Cross Correlation Spectroscopy is a rarely investigated version of Fluorescence Correlation Spectroscopy, in which the fluorescence signals from different observation volumes are cross-correlated. In the reported…

Optics · Physics 2008-06-13 Yoann Blancquaert , Jie Gao , Jacques Derouard , Antoine Delon

Optical interferometers may not require a phase-stable optical link between the stations if instead sources of quantum-mechanically entangled pairs could be provided to them, enabling long baselines. We developed a new variation of this…

Instrumentation and Methods for Astrophysics · Physics 2023-02-01 Zhi Chen , Andrei Nomerotski , Anže Slosar , Paul Stankus , Stephen Vintskevich

A new generation of telescopes with mirror diameters of 20 m or more, called extremely large telescopes (ELTs) has the potential to provide unprecedented imaging and spectroscopy of exo-planetary systems, if the difficulties in achieving…

Instrumentation and Methods for Astrophysics · Physics 2016-04-20 Richard A. Frazin

Recently, weak measurements were used to measure small effects that are transverse to the propagation direction of a light beam. Here we address the question whether weak measurements are also useful for measuring small longitudinal phase…

Quantum Physics · Physics 2010-07-12 Nicolas Brunner , Christoph Simon