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4D-flow magnetic resonance imaging (MRI) is an emerging imaging technique where spatiotemporal 3D blood velocity can be captured with full volumetric coverage in a single non-invasive examination. This enables qualitative and quantitative…

Image and Video Processing · Electrical Eng. & Systems 2020-04-16 Edward Ferdian , Avan Suinesiaputra , David Dubowitz , Debbie Zhao , Alan Wang , Brett Cowan , Alistair Young

We present a novel numerical algorithm developed to reconstuct pulsatile blood flow from ECG-gated CT angiography data. A block-based optimization method was constructed to solve the inverse problem corresponding to the Riccati-type…

Numerical Analysis · Mathematics 2015-11-26 Attila Lovas , Róbert Nagy , Elek Csobo , Brigitta Szilágyi , Péter Sótonyi

Image-based, patient-specific modelling of hemodynamics can improve diagnostic capabilities and provide complementary insights to better understand the hemodynamic treatment outcomes. However, computational fluid dynamics simulations remain…

Numerical Analysis · Mathematics 2025-02-18 Francesco Romor , Felipe Galarce , Jan Brüning , Leonid Goubergrits , Alfonso Caiazzo

Super-resolution is widely used in medical imaging to enhance low-quality data, reducing scan time and improving abnormality detection. Conventional super-resolution approaches typically rely on paired datasets of downsampled and original…

Computer Vision and Pattern Recognition · Computer Science 2026-02-18 Xiaoyi Wen , Fei Jiang

Systematic in vivo validations of computational models of the aortic valve remain scarce, despite successful validation against in vitro data. Utilizing a combination of computed tomography and 4D flow magnetic resonance imaging data, we…

Computational fluid dynamics (CFD) is increasingly used to study blood flows in patient-specific arteries for understanding certain cardiovascular diseases. The techniques work quite well for relatively simple problems, but need…

Computational Physics · Physics 2018-10-11 Fande Kong , Vitaly Kheyfets , Ender Finol , Xiao-Chuan Cai

Blood flow is sensitive to disease and provides insight into cardiac function, making flow field analysis valuable for diagnosis. However, while safer than radiation-based imaging and more suitable for patients with medical implants,…

Machine Learning · Computer Science 2025-11-04 Viraj Patel , Lisa Kreusser , Katharine Fraser

Cerebrovascular diseases such as brain aneurysms are a primary cause of adult disability. The flow dynamics in brain arteries, both during periods of rest and increased activity, are known to be a major factor in the risk of aneurysm…

Distributed, Parallel, and Cluster Computing · Computer Science 2015-04-30 Mohamed A. Itani , Ulf D. Schiller , Sebastian Schmieschek , James Hetherington , Miguel O. Bernabeu , Hoskote Chandrashekar , Fergus Robertson , Peter V. Coveney , Derek Groen

We investigate the prediction of the turbulent flow around a canonical square cylinder at Re= 22000 solving the unsteady Reynolds-averaged Navier-Stokes (URANS) equations. The limitations of URANS modelling are overcome through the…

Fluid Dynamics · Physics 2022-03-09 Markus Zauner , Vincent Mons , Olivier Marquet , Benjamin Leclaire

We introduce a continuous (downscaling) data assimilation algorithm for the 2D B\'enard convection problem using vorticity or local circulation measurements only. In this algorithm, a nudging term is added to the vorticity equation to…

Analysis of PDEs · Mathematics 2017-09-11 Aseel Farhat , Hans Johnston , Michael S. Jolly , Edriss S. Titi

It is known that the maximum diameter for the rupture-risk assessment of the abdominal aortic aneurysm is a generally good method, but not sufficient. Alternative features obtained with computational modeling may provide additional useful…

Computational Engineering, Finance, and Science · Computer Science 2020-03-16 Shanlin Qin , Rongliang Chen , Bokai Wu , Jia Liu , Wen-Shin Shiu , Zhengzheng Yan , Xiao-Chuan Cai

Morphology of cardiovascular tissue is influenced by the unsteady behavior of the blood flow and vice versa. Therefore, the pathogenesis of several cardiovascular diseases is directly affected by the blood-flow dynamics. Understanding flow…

Obtaining system parameters and reconstructing the full flow state from limited velocity observations using conventional fluid dynamics solvers can be prohibitively expensive. Here we employ machine learning algorithms to overcome the…

Fluid Dynamics · Physics 2024-10-17 Vladimir Parfenyev , Mark Blumenau , Ilia Nikitin

In this article, we provide a methodology to reconstruct high-Reynolds number turbulent mean-flows from few time-averaged measurements. A turbulent flow over a backward-facing step at Re = 28275 is considered to illustrate the potential of…

Fluid Dynamics · Physics 2020-09-23 Lucas Franceschini , Denis Sipp , Olivier Marquet

We show how the 3DVAR data assimilation methodology can be used in the astrophysical context of a two-dimensional convection flow. We study the way this variational approach finds best estimates of the current state of the flow from a…

Solar and Stellar Astrophysics · Physics 2013-08-09 Andreas Svedin , Milena C. Cuellar , Axel Brandenburg

One of the challenges encountered by computational simulations at exascale is the reliability of simulations in the face of hardware and software faults. These faults, expected to increase with the complexity of the computational systems,…

Fluid Dynamics · Physics 2019-02-19 Marc T. Henry de Frahan , Ray W. Grout

The full-field reconstruction of three-dimensional (3D) turbulent flows from sparse experimental measurements remains a significant challenge, particularly for flows exhibiting complex 3D flow separation. In this work, we address this…

We performed numerical simulations of blood flow in arteries with a variable stiffness and cross-section at rest using a finite volume method coupled with a hydrostatic reconstruction of the variables at the interface of each mesh cell. The…

Numerical Analysis · Mathematics 2015-09-15 Olivier Delestre , Arthur Ghigo , Jose-Maria Fullana , Pierre-Yves Lagrée

Cardiovascular diseases (CVDs) are the leading causes of mortality worldwide. The contraction and relaxation of left ventricle (LV) is the main driving force of blood circulation. Altered LV hemodynamics is believed to be associated with…

Medical Physics · Physics 2019-11-04 Fanwei Kong , Christoph Augustin , Kevin Sack , Shawn Shadden

We present a novel framework for assimilating planar PIV experimental data using a variational approach to enhance the predictions of the Spalart-Allmaras RANS turbulence model. Our method applies three-dimensional constraints to the…

Fluid Dynamics · Physics 2026-01-27 Uttam Cadambi Padmanaban , Bharathram Ganapathisubramani , Sean Symon