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Aging is driven by subcellular processes that are relatively well-understood. However the qualitative mechanisms and quantitative dynamics of how these micro-level failures cascade to a macro-level catastrophe in a tissue or organs remain…

Tissues and Organs · Quantitative Biology 2021-02-03 Gurdip Uppal , Gokhan Bahcecioglu , Pinar Zorlutuna , Dervis Can Vural

Aging, the dependence of the dynamics of a physical process on the time $t_a$ since its original preparation, is observed in systems ranging from the motion of charge carriers in amorphous semiconductors over the blinking dynamics of…

Statistical Mechanics · Physics 2014-12-24 Henning Kruesemann , Aljaz Godec , Ralf Metzler

Continuous time random walk (CTRW) subdiffusion along with the associated fractional Fokker-Planck equation (FFPE) is traditionally based on the premise of random clock with divergent mean period. This work considers an alternative CTRW and…

Statistical Mechanics · Physics 2014-09-24 Igor Goychuk

In many physical situations involving diverse length scales, waves or rays representing them travel through media characterized by spatially smooth, random, modest refactive index variations. "Primary" diffraction (by individual…

Classical Physics · Physics 2021-12-14 Eric J Heller , Ragnar Fleischmann , Tobias Kramer

We study the effect of advection and small diffusion on passive tracers. The advecting velocity field is assumed to have mean zero and to possess time-periodic stream lines. Using a canonical transform to action-angle variables followed by…

Fluid Dynamics · Physics 2009-11-13 Tobias Schaefer , Andrew C. Poje , Jesenko Vukadinovic

Experiments on particles' motion in living cells show that it is often subdiffusive. This subdiffusion may be due to trapping, percolation-like structures, or viscoelatic behavior of the medium. While the models based on trapping (leading…

Disordered Systems and Neural Networks · Physics 2015-06-11 Yasmine Meroz , Igor M. Sokolov , Joseph Klafter

Commonly, normal diffusive behavior is characterized by a linear dependence of the second central moment on time, $< x^2(t) >\propto t$, while anomalous behavior is expected to show a different time dependence, $ < x^2(t) > \propto…

Statistical Mechanics · Physics 2015-05-13 Bartlomiej Dybiec , Ewa Gudowska-Nowak

The presence of global conserved quantities in interacting systems generically leads to diffusive transport at late times. Here, we show that systems conserving the dipole moment of an associated global charge, or even higher moment…

Strongly Correlated Electrons · Physics 2020-12-22 Johannes Feldmeier , Pablo Sala , Giuseppe de Tomasi , Frank Pollmann , Michael Knap

We investigate the transport dynamics of elongated particles in cellular vortical flows that undergo spatial oscillations over time. Experimental flow visualizations reveal mixed flow fields with chaotic and elliptic regions coexisting.…

Fluid Dynamics · Physics 2025-08-14 Shiyuan Hu , Xiuyuan Yang , Nan Luo , Jun Zhang , Xingkun Man

We present a model for diffusion in a molecularly crowded environment. The model consists of random barriers in percolation network. Random walks in the presence of slowly moving barriers show normal diffusion for long times, but anomalous…

Subcellular Processes · Quantitative Biology 2007-06-06 Dietrich Stauffer , Christian Schulze , Dieter W. Heermann

We explore the fractional advection-diffusion equation and rare events associated with the ACTRW model. When waiting times have a finite mean but infinite variance, and the displacements follow a narrow distribution, the fractional operator…

Statistical Mechanics · Physics 2025-02-18 Yuanze Hong , Tian zhou , Wanli Wang

The transport equation of active motion is generalised to consider time-fractional dynamics for describing the anomalous diffusion of self-propelled particles observed in many different systems. In the present study, we consider an…

Statistical Mechanics · Physics 2023-10-27 Francisco J. Sevilla , Guillermo Chacón-Acosta , Trifce Sandev

We demonstrate aging behavior in a simple non-linear system. Our model is a chaotic map which generates deterministically sub-diffusion. Asymptotic behaviors of the diffusion process are described using aging continuous time random walks,…

Statistical Mechanics · Physics 2007-05-23 E. Barkai

Transport across heterogeneous, patchy environments is a ubiquitous phenomenon spanning fields of study including ecological movement, intracellular transport and regions of specialised function in a cell. These regions or patches may be…

Statistical Mechanics · Physics 2017-10-06 Sergei Fedotov , Helena Stage

Continuous-time random walks are generalisations of random walks frequently used to account for the consistent observations that many molecules in living cells undergo anomalous diffusion, i.e. subdiffusion. Here, we describe the…

Analysis of PDEs · Mathematics 2015-03-31 Hugues Berry , Thomas Lepoutre , Álvaro Mateos González

The diffusion of a particle in a crowded environment typically proceeds through three regimes: for very short times the particle diffuses freely until it collides with an obstacle for the first time, while for very long times diffusion the…

Biological Physics · Physics 2019-10-09 Nguiya P. Neo , Gary W. Slater

We study a one dimensional generalization of the exponential trap model using both numerical simulations and analytical approximations. We obtain the asymptotic shape of the average diffusion front in the sub-diffusive phase. Our central…

Disordered Systems and Neural Networks · Physics 2009-11-07 E. M. Bertin , J. -P. Bouchaud

We consider the dynamics of a separable Continuous Time Random Walk (CTRW) when the random walker is biased by a velocity field in a uniformly growing domain. Concrete examples for such domains include growing biological cells or lipid…

Statistical Mechanics · Physics 2020-08-26 F. Le Vot , E. Abad , R. Metzler , S. B. Yuste

We investigate the outflux of ions through the channels in a cell membrane. The channels undergo an open/close cycle according to a periodic schedule. Our study is based both on theoretical considerations relying on homogenization theory,…

Analysis of PDEs · Mathematics 2014-11-21 D. Andreucci , D. Bellaveglia , E. N. M. Cirillo

The spread of a particular trait in a cell population often is modelled by an appropriate system of ordinary differential equations describing how the sizes of subpopulations of the cells with the same genome change in time. On the other…

Dynamical Systems · Mathematics 2016-05-26 J. Banasiak , A. Falkiewicz