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The cycleGAN is becoming an influential method in medical image synthesis. However, due to a lack of direct constraints between input and synthetic images, the cycleGAN cannot guarantee structural consistency between these two images, and…

Computer Vision and Pattern Recognition · Computer Science 2018-09-13 Heran Yang , Jian Sun , Aaron Carass , Can Zhao , Junghoon Lee , Zongben Xu , Jerry Prince

Computed tomography (CT) is a widely used imaging modality for medical diagnosis and treatment. In electroencephalography (EEG), CT imaging is necessary for co-registering with magnetic resonance imaging (MRI) and for creating more accurate…

Medical Physics · Physics 2019-06-12 Andreas D. Lauritzen , Xenophon Papademetris , Sergei Turovets , John A. Onofrey

In this paper we will focus on the potential and on the challenges associated with the development of an integrated brain and spinal cord modelling framework for processing MR neuroimaging data. The aim of the work is to explore how a…

Computer Vision and Pattern Recognition · Computer Science 2017-07-06 Claudia Blaiotta , Patrick Freund , M. Jorge Cardoso , John Ashburner

In genome-wide prediction, independence of marker allele substitution effects is typically assumed; however, since early stages of this technology it has been known that nature points to correlated effects. In statistics, graphical models…

Quantitative Methods · Quantitative Biology 2017-09-21 Carlos Alberto Martínez , Kshitij Khare , Syed Rahman , Mauricio A. Elzo

MRI provides superior soft tissue contrast without ionizing radiation; however, the absence of electron density information limits its direct use for dose calculation. As a result, current radiotherapy workflows rely on combined MRI and CT…

Computer Vision and Pattern Recognition · Computer Science 2026-02-06 Zolnamar Dorjsembe , Hung-Yi Chen , Furen Xiao , Hsing-Kuo Pao

Synthesized medical images have several important applications, e.g., as an intermedium in cross-modality image registration and as supplementary training samples to boost the generalization capability of a classifier. Especially,…

Computer Vision and Pattern Recognition · Computer Science 2019-03-19 Zizhao Zhang , Lin Yang , Yefeng Zheng

Electron density maps must be accurately estimated to achieve valid dose calculation in MR-only radiotherapy. The goal of this study is to assess whether two deep learning models, the conditional generative adversarial network (cGAN) and…

A novel Gaussian mixture model (GMM) aided sparse Bayesian learning (SBL) framework is proposed for channel state information (CSI) estimation in orthogonal time-frequency space (OTFS) modulated systems. The key attribute of the proposed…

Signal Processing · Electrical Eng. & Systems 2026-03-31 Surbhi Gehlot , Suraj Srivastava , Sandeep Kumar Yadav , Lajos Hanzo

Objective: Positron Emission Tomography (PET) has been a commonly used imaging modality in broad clinical applications. One of the most important tradeoffs in PET imaging is between image quality and radiation dose: high image quality comes…

Image and Video Processing · Electrical Eng. & Systems 2024-04-18 Shaoyan Pan , Elham Abouei , Junbo Peng , Joshua Qian , Jacob F Wynne , Tonghe Wang , Chih-Wei Chang , Justin Roper , Jonathon A Nye , Hui Mao , Xiaofeng Yang

Cone-Beam Computed Tomography (CBCT) is widely used for intraoperative imaging due to its rapid acquisition and low radiation dose. However, CBCT images typically suffer from artifacts and lower visual quality compared to conventional…

Image and Video Processing · Electrical Eng. & Systems 2025-07-09 Maximilian Tschuchnig , Lukas Lamminger , Philipp Steininger , Michael Gadermayr

In medical image synthesis, model training could be challenging due to the inconsistencies between images of different modalities even with the same patient, typically caused by internal status/tissue changes as different modalities are…

Image and Video Processing · Electrical Eng. & Systems 2021-09-16 Hajar Emami , Ming Dong , Siamak Nejad-Davarani , Carri Glide-Hurst

Background: Individual skull models of bone density and geometry are important when planning the expected transcranial ultrasound acoustic field and estimating mechanical and thermal safety in low-intensity transcranial ultrasound…

Although extensive research exists in spatial modeling, few studies have addressed finite mixture model-based clustering methods for spatial data. Finite mixture models, especially Gaussian mixture models, particularly suffer from high…

Graph-based reasoning over skeleton data has emerged as a promising approach for human action recognition. However, the application of prior graph-based methods, which predominantly employ whole temporal sequences as their input, to the…

Computer Vision and Pattern Recognition · Computer Science 2023-03-27 Lukas Hedegaard , Negar Heidari , Alexandros Iosifidis

Computed tomography (CT) plays an important role in lung malignancy diagnostics and therapy assessment and facilitating precision medicine delivery. However, the use of personalized imaging protocols poses a challenge in large-scale…

Image and Video Processing · Electrical Eng. & Systems 2020-04-06 Md Selim , Jie Zhang , Baowei Fei , Guo-Qiang Zhang , Jin Chen

Transcranial MRI-guided focused ultrasound (TcMRgFUS) is a therapeutic ultrasound method that focuses sound through the skull to a small region noninvasively under MRI guidance. It is clinically approved to thermally ablate regions of the…

Computer Vision and Pattern Recognition · Computer Science 2022-02-23 Han Liu , Michelle K. Sigona , Thomas J. Manuel , Li Min Chen , Charles F. Caskey , Benoit M. Dawant

Normative modeling has recently been proposed as an alternative for the case-control approach in modeling heterogeneity within clinical cohorts. Normative modeling is based on single-output Gaussian process regression that provides coherent…

Machine Learning · Statistics 2018-06-07 Seyed Mostafa Kia , Andre Marquand

Although convolutional neural networks (CNNs) currently dominate competitions on image segmentation, for neuroimaging analysis tasks, more classical generative approaches based on mixture models are still used in practice to parcellate…

Computer Vision and Pattern Recognition · Computer Science 2019-05-29 Mikael Brudfors , Yaël Balbastre , John Ashburner

We consider maximum likelihood estimation for Gaussian Mixture Models (Gmms). This task is almost invariably solved (in theory and practice) via the Expectation Maximization (EM) algorithm. EM owes its success to various factors, of which…

Machine Learning · Statistics 2018-06-04 Reshad Hosseini , Suvrit Sra

This work provides a computationally efficient and statistically consistent moment-based estimator for mixtures of spherical Gaussians. Under the condition that component means are in general position, a simple spectral decomposition…

Machine Learning · Computer Science 2012-10-30 Daniel Hsu , Sham M. Kakade
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