Related papers: Optimal Trajectories of Brain State Transitions
Finding minimal time and establishing the structure of the corresponding optimal controls which can transfer a given initial state of a quantum system into a given target state is a key problem of quantum control. In this work, this problem…
We report measurements of the brain activity of subjects engaged in behavioral exchanges with their environments. We observe brain states which are characterized by coordinated oscillation of populations of neurons that are changing rapidly…
Activity in neocortex exhibits a range of behaviors, from irregular to temporally precise, and from weakly to strongly correlated. So far there has been no single theoretical framework that could explain all these behaviors, leaving open…
Metastable brain dynamics are characterized by abrupt, jump-like modulations so that the neural activity in single trials appears to unfold as a sequence of discrete, quasi-stationary states. Evidence that cortical neural activity unfolds…
Loss of cortical integration and changes in the dynamics of electrophysiological brain signals characterize the transition from wakefulness towards unconsciousness. The common mechanism underlying these observations remains unknown. In this…
Functional brain networks can change rapidly as a function of stimuli or cognitive shifts. Tracking dynamic functional connectivity is particularly challenging as it requires estimating the structure of the network at each moment as well as…
Dynamic instability in the cytoskeleton underlies a great many vital cellular processes. In neurons, it is thought to play a role in information processing and the establishment of synaptic connections. It is from this interneuronal…
The functional brain network emerges from the complex, coordinated activity of distinct yet connected regions, which underlie the diverse repertoire of human cognitive functions. Structural Balance Theory (SBT) has been successfully applied…
We review how sensorimotor control is dictated by interacting neural populations, optimal feedback mechanisms, and the biomechanics of bodies. First, we outline the distributed anatomical loops that shuttle sensorimotor signals between…
The organization of interactions in complex systems can be described by networks connecting different units. These graphs are useful representations of the local and global complexity of the underlying systems. The origin of their…
Human brains are arguably the most complex entities known. Composed of billions of neurons, connected via a highly detailed structure where the underlying method by which functionality occurs is still debated. Here we consider one theory…
The threshold voltage for action potential generation is a key regulator of neuronal signal transduction, yet the mechanism of its dynamic variation is still not well described. In this paper, we propose that threshold phenomena can be…
To set the stage for viewing Consciousness in terms of brain phase space dynamics and criticality, I will first review currently prominent theoretical conceptualizations and, where appropriate, identify ill-advised and flawed notions in…
Anatomic connections between brain areas affect information flow between neuronal circuits and the synchronization of neuronal activity. However, such structural connectivity does not coincide with effective connectivity, related to the…
Primates display a marked ability to learn habits in uncertain and dynamic environments. The associated perceptions and actions of such habits engage distributed neural circuits. Yet, precisely how such circuits support the computations…
We develop a mathematical model of information transmission across the biological neural network of the human brain. The overall function of the brain consists of the emergent processes resulting from the spread of information through the…
Neural activity fluctuates over a wide range of timescales within and across brain areas. Experimental observations suggest that diverse neural timescales reflect information in dynamic environments. However, how timescales are defined and…
We apply the framework of optimal nonlinear control to steer the dynamics of a whole-brain network of FitzHugh-Nagumo oscillators. Its nodes correspond to the cortical areas of an atlas-based segmentation of the human cerebral cortex, and…
To explain consciousness as a physical process we must acknowledge the role of energy in the brain. Energetic activity is fundamental to all physical processes and causally drives biological behaviour. Recent neuroscientific evidence can be…
Recent experiments have highlighted how collective dynamics in networks of brain regions affect behavior and cognitive function. In this paper we show that a simple, homogeneous system of densely connected oscillators representing the…