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Increasing use of CT in modern medical practice has raised concerns over associated radiation dose. Reduction of radiation dose associated with CT can increase noise and artifacts, which can adversely affect diagnostic confidence. Denoising…

Computer Vision and Pattern Recognition · Computer Science 2017-02-24 Qingsong Yang , Pingkun Yan , Mannudeep K. Kalra , Ge Wang

This is a review paper on some of the physics, modeling, and iterative algorithms in proton computed tomography (pCT) image reconstruction. The primary challenge in pCT image reconstruction lies in the degraded spatial resolution resulting…

Medical Physics · Physics 2015-10-30 Scott Penfold , Yair Censor

In a standard computed tomography (CT) image, pixels having the same Hounsfield Units (HU) can correspond to different materials and it is, therefore, challenging to differentiate and quantify materials. Dual-energy CT (DECT) is desirable…

Medical Physics · Physics 2019-11-01 Wei Zhao , Tianling Lv , Peng Gao , Liyue Shen , Xianjin Dai , Kai Cheng , Mengyu Jia , Yang Chen , Lei Xing

Low Dose CT Denoising research aims to reduce the risks of radiation exposure to patients. Recently researchers have used deep learning to denoise low dose CT images with promising results. However, approaches that use mean-squared-error…

Image and Video Processing · Electrical Eng. & Systems 2024-09-05 Sepehr Ataei , Javad Alirezaie , Paul Babyn

A major challenge in computed tomography (CT) is to reduce X-ray dose to a low or even ultra-low level while maintaining the high quality of reconstructed images. We propose a new method for CT reconstruction that combines penalized…

Machine Learning · Statistics 2017-07-11 Xuehang Zheng , Zening Lu , Saiprasad Ravishankar , Yong Long , Jeffrey A. Fessler

Three-dimensional (3D) reconstruction of head Computed Tomography (CT) images elucidates the intricate spatial relationships of tissue structures, thereby assisting in accurate diagnosis. Nonetheless, securing an optimal head CT scan…

Computer Vision and Pattern Recognition · Computer Science 2023-09-18 Bowen Zheng , Chenxi Huang , Yuemei Luo

Single-Photon Emission Computed Tomography (SPECT) is widely applied for the diagnosis of ischemic heart diseases. Low-dose (LD) SPECT aims to minimize radiation exposure but leads to increased image noise. Limited-angle (LA) SPECT enables…

Computer Vision and Pattern Recognition · Computer Science 2023-05-18 Xiongchao Chen , Bo Zhou , Huidong Xie , Xueqi Guo , Qiong Liu , Albert J. Sinusas , Chi Liu

The restoration of images affected by blur and noise has been widely studied and has broad potential for applications including in medical imaging modalities like computed tomography (CT). Although the blur and noise in CT images can be…

Medical Physics · Physics 2024-07-23 Yijie Yuan , Grace J. Gang , J. Webster Stayman

Purpose: Optoacoustic tomography (OAT) is inherently a three-dimensional (3D) inverse problem. However, most studies of OAT image reconstruction still employ two-dimensional (2D) imaging models. One important reason is because 3D image…

Medical Physics · Physics 2013-04-09 Kun Wang , Chao Huang , Yu-Jiun Kao , Cheng-Ying Chou , Alexander A. Oraevsky , Mark A. Anastasio

As a sensitive functional imaging technique, positron emission tomography (PET) plays a critical role in early disease diagnosis. However, obtaining a high-quality PET image requires injecting a sufficient dose (standard dose) of…

Image and Video Processing · Electrical Eng. & Systems 2024-12-06 Caiwen Jiang , Mianxin Liu , Kaicong Sun , Dinggang Shen

The problem of reconstruction of digital images from their degraded measurements is regarded as a problem of central importance in various fields of engineering and imaging sciences. In such cases, the degradation is typically caused by the…

Computer Vision and Pattern Recognition · Computer Science 2010-01-06 E. Shaked , O. Michailovich

Limited view tomographic reconstruction aims to reconstruct a tomographic image from a limited number of sinogram or projection views arising from sparse view or limited angle acquisitions that reduce radiation dose or shorten scanning…

Image and Video Processing · Electrical Eng. & Systems 2020-09-04 Bo Zhou , S. Kevin Zhou , James S. Duncan , Chi Liu

While Computed Tomography (CT) reconstruction from X-ray sinograms is necessary for clinical diagnosis, iodine radiation in the imaging process induces irreversible injury, thereby driving researchers to study sparse-view CT reconstruction,…

Image and Video Processing · Electrical Eng. & Systems 2021-11-29 Ce Wang , Kun Shang , Haimiao Zhang , Qian Li , Yuan Hui , S. Kevin Zhou

Photon-counting computed tomography (PCCT) has emerged as a promising imaging technique, enabling spectral imaging and material decomposition (MD). However, images typically suffer from a low signal-to-noise ratio (SNR) due to constraints…

Spectral Computed Tomography (CT) is an emerging technology that enables to estimate the concentration of basis materials within a scanned object by exploiting different photon energy spectra. In this work, we aim at efficiently solving a…

Optimization and Control · Mathematics 2021-03-26 Alessandro Perelli , Martin S. Andersen

Low-Dose computer tomography (LDCT) is an ideal alternative to reduce radiation risk in clinical applications. Although supervised-deep-learning-based reconstruction methods have demonstrated superior performance compared to conventional…

Image and Video Processing · Electrical Eng. & Systems 2024-05-24 Feng Wang , Renfang Wang , Hong Qiu

Computed tomography (CT) has been used worldwide as a non-invasive test to assist in diagnosis. However, the ionizing nature of X-ray exposure raises concerns about potential health risks such as cancer. The desire for lower radiation doses…

Image and Video Processing · Electrical Eng. & Systems 2024-07-01 Yucheng Lu , Zhixin Xu , Moon Hyung Choi , Jimin Kim , Seung-Won Jung

Low-dose computed tomography (LDCT) is critical for minimizing radiation exposure, but it often leads to increased noise and reduced image quality. Traditional denoising methods, such as iterative optimization or supervised learning, often…

Computer Vision and Pattern Recognition · Computer Science 2025-09-23 Debopom Sutradhar , Ripon Kumar Debnath , Mohaimenul Azam Khan Raiaan , Yan Zhang , Reem E. Mohamed , Sami Azam

Computed tomography has propelled scientific advances in fields from biology to materials science. This technology allows for the elucidation of 3-dimensional internal structure by the attenuation of x-rays through an object at different…

Computer Vision and Pattern Recognition · Computer Science 2022-11-02 Rey Mendoza , Minh Nguyen , Judith Weng Zhu , Vincent Dumont , Talita Perciano , Juliane Mueller , Vidya Ganapati

The iterative refinement method (IRM) has been very successfully applied in many different fields for examples the modern quantum chemical calculation and CT image reconstruction. It is proved that the refinement method can create an exact…

Medical Physics · Physics 2015-12-23 Kang Yang , Kevin Yang , Xintie Yang , Shuang-Ren Zhao