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Multimodal sentiment analysis (MSA) aims to predict human sentiment from textual, acoustic, and visual information in videos. Recent studies improve multimodal fusion by modeling modality interaction and assigning different modality…

Multimedia · Computer Science 2026-04-08 Chen Su , Yuanhe Tian , Yan Song

Witnessing subsystems for probabilistic reachability thresholds in discrete Markovian models are an important concept both as diagnostic information on why a property holds, and as input to refinement algorithms. We present SWITSS, a tool…

Logic in Computer Science · Computer Science 2020-08-11 Simon Jantsch , Hans Harder , Florian Funke , Christel Baier

Protein structure prediction is a challenging and unsolved problem in computer science. Proteins are the sequence of amino acids connected together by single peptide bond. The combinations of the twenty primary amino acids are the…

Computational Engineering, Finance, and Science · Computer Science 2015-10-12 Mahmood A. Rashid , Firas Khatib , Abdul Sattar

We introduce Metis, a foundation model for unified speech generation. Unlike previous task-specific or multi-task models, Metis follows a pre-training and fine-tuning paradigm. It is pre-trained on large-scale unlabeled speech data using…

Sound · Computer Science 2025-02-06 Yuancheng Wang , Jiachen Zheng , Junan Zhang , Xueyao Zhang , Huan Liao , Zhizheng Wu

In this study, we expand upon the FLIP benchmark-designed for evaluating protein fitness prediction models in small, specialized prediction tasks-by assessing the performance of state-of-the-art large protein language models, including…

Machine Learning · Computer Science 2025-01-31 Manuel F. Mollon , Joaquin Gonzalez-Rodriguez , Alicia Lozano-Diez , Daniel Ramos , Doroteo T. Toledano

Designing protein mutants of both high stability and activity is a critical yet challenging task in protein engineering. Here, we introduce PRIME, a deep learning model, which can suggest protein mutants of improved stability and activity…

Efficient Maximum Inner Product Search (MIPS) is an important task that has a wide applicability in recommendation systems and classification with a large number of classes. Solutions based on locality-sensitive hashing (LSH) as well as…

Machine Learning · Computer Science 2015-12-01 Alex Auvolat , Sarath Chandar , Pascal Vincent , Hugo Larochelle , Yoshua Bengio

Retrieving code functions, classes or files that are relevant in order to solve a given user query, bug report or feature request from large codebases is a fundamental challenge for Large Language Model (LLM)-based coding agents. Agentic…

Software Engineering · Computer Science 2026-02-09 Shravan Chaudhari , Rahul Thomas Jacob , Mononito Goswami , Jiajun Cao , Shihab Rashid , Christian Bock

Motivation: In the last few years a growing interest in biology has been shifting towards the problem of optimal information extraction from the huge amount of data generated via large scale and high-throughput techniques. One of the most…

Quantitative Methods · Quantitative Biology 2007-05-23 M. Leone , A. Pagnani

Time series models are ubiquitous in science, arising in any situation where researchers seek to understand how a system's behaviour changes over time. A key problem in time series modelling is \emph{inference}; determining properties of…

Mathematical Software · Computer Science 2020-01-13 Michael Clerx , Martin Robinson , Ben Lambert , Chon Lok Lei , Sanmitra Ghosh , Gary R. Mirams , David J. Gavaghan

This paper summarizes the ideas and key concepts in MISE (Memory Interference-induced Slowdown Estimation), which was published in HPCA 2013 [97], and examines the work's significance and future potential. Applications running concurrently…

Hardware Architecture · Computer Science 2018-05-16 Lavanya Subramanian , Vivek Seshadri , Yoongu Kim , Ben Jaiyen , Onur Mutlu

Multimodal semantic communication has gained widespread attention due to its ability to enhance downstream task performance. A key challenge in such systems is the effective fusion of features from different modalities, which requires the…

Image and Video Processing · Electrical Eng. & Systems 2025-09-03 Haoshuo Zhang , Yufei Bo , Hongwei Zhang , Meixia Tao

Systematic identification of protein function is a key problem in current biology. Most traditional methods fail to identify functionally equivalent proteins if they lack similar sequences, structural data or extensive manual annotations.…

Genomics · Quantitative Biology 2016-03-08 Dan Ofer

Background: Increasingly, decision-making in healthcare relies on computer models, be it clinical prediction models at point of care or decision-analytic models at the policymaking level. Given the important role models play in both…

Computation · Statistics 2022-02-22 Amin Adibi , Stephanie Harvard , Mohsen Sadatsafavi

Protein inference plays a vital role in the proteomics study. Two major approaches could be used to handle the problem of protein inference; top-down and bottom-up. This paper presents a framework for protein inference, which uses hardware…

Computational Engineering, Finance, and Science · Computer Science 2014-03-07 S. M. Vidanagamachchi , S. D. Dewasurendra , R. G. Ragel

Recent advances in cross-prompt automated essay scoring (AES) typically train models jointly on all source prompts, often requiring additional access to unlabeled target prompt essays simultaneously. However, using all sources is suboptimal…

Computation and Language · Computer Science 2025-05-27 Sanwoo Lee , Kun Liang , Yunfang Wu

Motivation: Assigning statistical significance accurately has become increasingly important as meta data of many types, often assembled in hierarchies, are constructed and combined for further biological analyses. Statistical inaccuracy of…

Quantitative Methods · Quantitative Biology 2014-07-25 Gelio Alves , Yi-Kuo Yu

Inference on time series data is a common requirement in many scientific disciplines and internet of things (IoT) applications, yet there are few resources available to domain scientists to easily, robustly, and repeatably build such…

Mathematical Software · Computer Science 2016-09-16 Brett Naul , Stéfan van der Walt , Arien Crellin-Quick , Joshua S. Bloom , Fernando Pérez

Protein structure similarity search (PSSS), which tries to search proteins with similar structures, plays a crucial role across diverse domains from drug design to protein function prediction and molecular evolution. Traditional…

Machine Learning · Computer Science 2024-11-14 Jin Han , Wu-Jun Li

Understanding and predicting polymer solubility in various solvents is critical for applications ranging from recycling to pharmaceutical formulation. This work presents a deep learning framework that predicts polymer solubility, expressed…

Machine Learning · Computer Science 2025-12-11 Andrew Reinhard
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