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Emerging Big Data analytics and machine learning applications require a significant amount of computational power. While there exists a plethora of large-scale data processing frameworks which thrive in handling the various complexities of…

Distributed, Parallel, and Cluster Computing · Computer Science 2019-06-26 Jan S. Rellermeyer , Sobhan Omranian Khorasani , Dan Graur , Apourva Parthasarathy

The last twenty years have witnessed molecular data emerge as a primary research instrument in most branches of mycology. Fungal systematics, taxonomy, and ecology have all seen tremendous progress and have undergone rapid, far-reaching…

Relation of genome sizes to organisms complexity is still described rather equivocally. Neither the number of genes (G-value), nor the total amount of DNA (C-value) correlates consistently with phenotype complexity. Using information theory…

Genomics · Quantitative Biology 2007-05-23 Dmitri V. Parkhomchuk

Introduction: Even in effectively conducted randomised trials, the probability of a successful study remains relatively low. With recent advances in the next-generation sequencing technologies, there is a rapidly growing number of…

A series of results of evolution supervised by genetic algorithms with interest to agricultural and horticultural fields are reviewed. New obtained original results from the use of genetic algorithms on structure-activity relationships are…

Neural and Evolutionary Computing · Computer Science 2010-09-07 Lorentz Jäntschi , Sorana D. Bolboac{\ba} , Mugur C. Bălan , Radu E. Sestraş

Biosciences have been revolutionized by next generation sequencing (NGS) technologies in last years, leading to new perspectives in medical, industrial and environmental applications. And although our motivation comes from biosciences, the…

Distributed, Parallel, and Cluster Computing · Computer Science 2017-01-16 Bruno Dantas , Calmenelias Fleitas , Alexandre P. Francisco , José Simão , Cátia Vaz

Deep learning and other big data technologies have over time become very powerful and accurate. There are algorithms and models developed that have near human accuracy in their task. In health care, the amount of data available is massive…

Computers and Society · Computer Science 2019-09-09 Dinesh Samuel Sathia Raj , Vijayakumar V , Bharat Rawal , Longzhi Yang

Recent advances in DNA sequencing open prospects to make whole-genome analysis rapid and reliable, which is promising for various applications including personalized medicine. However, existing techniques for {\it de novo} genome assembly,…

Genomics is changing our understanding of humans, evolution, diseases, and medicines to name but a few. As sequencing technology is developed collecting DNA sequences takes less time thereby generating more genetic data every day. Today the…

Quantitative Methods · Quantitative Biology 2020-07-29 Sahand Salamat , Tajana Rosing

Motivation: Array Comparative Genomic Hybridization (aCGH) is used to scan the entire genome for variations in DNA copy number. A central task in the analysis of aCGH data is the segmentation into groups of probes sharing the same DNA copy…

Quantitative Methods · Quantitative Biology 2008-04-29 Erez Ben-Yaacov , Yonina Eldar

Although the applications of Non-Homogeneous Poisson Processes to model and study the threshold overshoots of interest in different time series of measurements have proven to provide good results, they needed to be complemented with an…

Applications · Statistics 2023-09-15 Biviana Marcela Suárez-Sierra , Arrigo Coen , Carlos Alberto Taimal

Generative AI systems have entered everyday academic, professional, and personal life with remarkable speed, yet most users encounter them as mysterious artifacts rather than intelligible systems. This chapter discusses large language…

Computers and Society · Computer Science 2026-04-21 John T. Behrens

Online genealogy datasets contain extensive information about millions of people and their past and present family connections. This vast amount of data can assist in identifying various patterns in human population. In this study, we…

Social and Information Networks · Computer Science 2014-01-07 Michael Fire , Yuval Elovici

The continuing, explosive developments in generative artificial intelligence (GenAI), built on large language models and related algorithms, has led to much excitement and speculation about the potential impact of this new technology.…

Computers and Society · Computer Science 2025-03-11 Veda C. Storey , Wei Thoo Yue , J. Leon Zhao , Roman Lukyanenko

With ongoing developments and innovations in single-cell RNA sequencing methods, advancements in sequencing performance could empower significant discoveries as well as new emerging possibilities to address biological and medical…

Applications · Statistics 2019-12-19 Jiawei Long , Yu Xia

Generative Knowledge Graph Construction (KGC) refers to those methods that leverage the sequence-to-sequence framework for building knowledge graphs, which is flexible and can be adapted to widespread tasks. In this study, we summarize the…

Computation and Language · Computer Science 2023-09-19 Hongbin Ye , Ningyu Zhang , Hui Chen , Huajun Chen

The analysis of biological sequencing data has been one of the biggest applications of string algorithms. The approaches used in many such applications are based on the analysis of k-mers, which are short fixed-length strings present in a…

Data Structures and Algorithms · Computer Science 2020-06-15 Rayan Chikhi , Jan Holub , Paul Medvedev

DNA microarrays are a relatively new technology that can simultaneously measure the expression level of thousands of genes. They have become an important tool for a wide variety of biological experiments. One of the most common goals of DNA…

Methodology · Statistics 2013-07-02 Eric Bair

The human microbiome is the ensemble of genes in the microbes that live inside and on the surface of humans. Because microbial sequencing information is now much easier to come by than phenotypic information, there has been an explosion of…

Populations and Evolution · Quantitative Biology 2014-07-08 Frederick A Matsen

The rapid development of high-throughput sequencing technologies has led to an explosive increase in biological sequence data, making sequence clustering a fundamental task in large-scale bioinformatics analyses. Unlike traditional…

Genomics · Quantitative Biology 2026-01-22 Simeng Zhang , Xinying Liu , Jun Lou , Mudi Jiang , Quan Zou , Zengyou He