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Age prediction based on appearances of different anatomies in medical images has been clinically explored for many decades. In this paper, we used deep learning to predict a persons age on Chest X-Rays. Specifically, we trained a CNN in…

Computer Vision and Pattern Recognition · Computer Science 2019-03-18 Alexandros Karargyris , Satyananda Kashyap , Joy T Wu , Arjun Sharma , Mehdi Moradi , Tanveer Syeda-Mahmood

Cardiovascular diseases (CVD) remain a leading health concern and contribute significantly to global mortality rates. While clinical advancements have led to a decline in CVD mortality, accurately identifying individuals who could benefit…

Image and Video Processing · Electrical Eng. & Systems 2024-11-18 Minfeng Xu , Chen-Chen Fan , Yan-Jie Zhou , Wenchao Guo , Pan Liu , Jing Qi , Le Lu , Hanqing Chao , Kunlun He

Breast cancer is the most prevalent cancer among women and predicting pathologic complete response (pCR) after anti-cancer treatment is crucial for patient prognosis and treatment customization. Deep learning has shown promise in medical…

Image and Video Processing · Electrical Eng. & Systems 2024-10-02 Jonghun Kim , Hyunjin Park

The rich chemical information from tissue metabolomics provides a powerful means to elaborate tissue physiology or tumor characteristics at cellular and tumor microenvironment levels. However, the process of obtaining such information…

Purpose: To develop a novel deep-learning model that integrates radiomics analysis in a multi-dimensional feature fusion workflow for glioblastoma (GBM) post-resection survival prediction. Methods: A cohort of 235 GBM patients with complete…

Medical Physics · Physics 2022-03-14 Zongsheng Hu , Zhenyu Yang , Haozhao Zhang , Eugene Vaios , Kyle Lafata , Fang-Fang Yin , Chunhao Wang

Cardiovascular diseases state as one of the greatest risks of death for the general population. Late detection in heart diseases highly conditions the chances of survival for patients. Age, sex, cholesterol level, sugar level, heart rate,…

Background: While deep learning technology, which has the capability of obtaining latent representations based on large-scale data, can be a potential solution for the discovery of a novel aging biomarker, existing deep learning methods for…

Machine Learning · Computer Science 2023-02-02 Seong-Eun Moon , Ji Won Yoon , Shinyoung Joo , Yoohyung Kim , Jae Hyun Bae , Seokho Yoon , Haanju Yoo , Young Min Cho

Importance: Lung cancer is the leading cause of cancer mortality in the US, responsible for more deaths than breast, prostate, colon and pancreas cancer combined and it has been recently demonstrated that low-dose computed tomography (CT)…

Assessing coronary artery plaque segments in coronary CT angiography scans is an important task to improve patient management and clinical outcomes, as it can help to decide whether invasive investigation and treatment are necessary. In…

Risk prediction is central to both clinical medicine and public health. While many machine learning models have been developed to predict mortality, they are rarely applied in the clinical literature, where classification tasks typically…

Machine Learning · Statistics 2017-12-05 Maggie Makar , Marzyeh Ghassemi , David Cutler , Ziad Obermeyer

Radiomics is an active area of research focusing on high throughput feature extraction from medical images with a wide array of applications in clinical practice, such as clinical decision support in oncology. However, noise in low dose…

Quantitative Methods · Quantitative Biology 2021-09-07 Junhua Chen , Inigo Bermejo , Andre Dekker , Leonard Wee

Early diagnosis of pathological invasiveness of pulmonary adenocarcinomas using computed tomography (CT) imaging would alter the course of treatment of adenocarcinomas and subsequently improve the prognosis. Most of the existing systems use…

Computer Vision and Pattern Recognition · Computer Science 2019-09-27 Xiang Li , Jiechao Ma , Hongwei Li

Herein we propose a deep learning-based approach for the prediction of lung lesion response based on radiomic features extracted from clinical CT scans of patients in non-small cell lung cancer trials. The approach starts with the…

Image and Video Processing · Electrical Eng. & Systems 2020-03-09 Antong Chen , Jennifer Saouaf , Bo Zhou , Randolph Crawford , Jianda Yuan , Junshui Ma , Richard Baumgartner , Shubing Wang , Gregory Goldmacher

Background. Pre-operative risk assessments used in clinical practice are limited in their ability to identify risk for post-operative mortality. We hypothesize that electrocardiograms contain hidden risk markers that can help prognosticate…

Quantitative extraction of high-dimensional mineable data from medical images is a process known as radiomics. Radiomics is foreseen as an essential prognostic tool for cancer risk assessment and the quantification of intratumoural…

Heart failure hospitalization is a severe burden on healthcare. How to predict and therefore prevent readmission has been a significant challenge in outcomes research. To address this, we propose a deep learning approach to predict…

Computation and Language · Computer Science 2019-12-24 Xiong Liu , Yu Chen , Jay Bae , Hu Li , Joseph Johnston , Todd Sanger

As early detection of breast cancer strongly favors successful therapeutic outcomes, there is major commercial interest in optimizing breast cancer screening. However, current risk prediction models achieve modest performance and do not…

Image and Video Processing · Electrical Eng. & Systems 2025-09-03 Manon A. Dorster , Felix J. Dorfner , Mason C. Cleveland , Melisa S. Guelen , Jay Patel , Dania Daye , Jean-Philippe Thiran , Albert E. Kim , Christopher P. Bridge

Most deep learning models in medical imaging are trained on adult data with unclear performance on pediatric images. In this work, we aim to address this challenge in the context of automated anatomy segmentation in whole-body Computed…

Image and Video Processing · Electrical Eng. & Systems 2024-04-23 Chih-Ying Liu , Jeya Maria Jose Valanarasu , Camila Gonzalez , Curtis Langlotz , Andrew Ng , Sergios Gatidis

Renal cell carcinoma represents a significant global health challenge with a low survival rate. This research aimed to devise a comprehensive deep-learning model capable of predicting survival probabilities in patients with renal cell…

Computer Vision and Pattern Recognition · Computer Science 2023-07-10 Maryamalsadat Mahootiha , Hemin Ali Qadir , Jacob Bergsland , Ilangko Balasingham

Predicting future clinical events helps physicians guide appropriate intervention. Machine learning has tremendous promise to assist physicians with predictions based on the discovery of complex patterns from historical data, such as large,…