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It is shown that certain classes of differential equations arising from the modelling of chemical reaction networks have the following property: the state space is foliated by invariant subspaces each of which contains a unique equilibrium…

Classical Analysis and ODEs · Mathematics 2012-11-07 Murad Banaji , Janusz Mierczynski

For dynamical systems arising from chemical reaction networks, persistence is the property that each species concentration remains positively bounded away from zero, as long as species concentrations were all positive in the beginning. We…

Dynamical Systems · Mathematics 2016-07-29 Michael Marcondes de Freitas , Elisenda Feliu , Carsten Wiuf

Chemical reactions often proceed through the formation and the consumption of intermediate species. An example is the creation and subsequent degradation of the substrate-enzyme complexes in an enzymatic reaction. In this paper we provide a…

Dynamical Systems · Mathematics 2018-05-22 Daniele Cappelletti , Carsten Wiuf

In a recent paper it was shown that, for chemical reaction networks possessing a subtle structural property called concordance, dynamical behavior of a very circumscribed (and largely stable) kind is enforced, so long as the kinetics lies…

Molecular Networks · Quantitative Biology 2012-04-26 Guy Shinar , Martin Feinberg

The trend to equilibrium for reaction-diffusion systems modelling chemical reaction networks is investigated, in the case when reaction processes happen on subsets of the domain. We prove the convergence to equilibrium by directly showing…

Analysis of PDEs · Mathematics 2024-12-17 Laurent Desvillettes , Kim Dang Phung , Bao Quoc Tang

In this article we give an in depth overview of the recent advances in the field of equilibrium networks. After outlining this topic, we provide a novel way of defining equilibrium graph (network) ensembles. We illustrate this concept on…

Statistical Mechanics · Physics 2007-05-23 I. Farkas , I. Derenyi , G. Palla , T. Vicsek

Motivated by recent progress on the interplay between graph theory, dynamics, and systems theory, we revisit the analysis of chemical reaction networks described by mass action kinetics. For reaction networks possessing a thermodynamic…

Optimization and Control · Mathematics 2012-06-19 Arjan van der Schaft , Shodhan Rao , Bayu Jayawardhana

In this paper we present a general procedure that allows for the reduction or expansion of any network (considered as a weighted graph). This procedure maintains the spectrum of the network's adjacency matrix up to a set of eigenvalues…

Dynamical Systems · Mathematics 2011-11-15 L. A. Bunimovich , B. Z. Webb

Time-continuous dynamical systems defined on graphs are often used to model complex systems with many interacting components in a non-spatial context. In the reverse sense attaching meaningful dynamics to given 'interaction diagrams' is a…

Molecular Networks · Quantitative Biology 2010-07-02 Markus Kirkilionis , Luca Sbano

In this paper we discuss the question of how to decide when a general chemical reaction system is incapable of admitting multiple equilibria, regardless of parameter values such as reaction rate constants, and regardless of the type of…

Dynamical Systems · Mathematics 2009-07-17 Murad Banaji , Gheorghe Craciun

Analyzing qualitative behaviors of biochemical reactions using its associated network structure has proven useful in diverse branches of biology. As an extension of our previous work, we introduce a graph-based framework to calculate steady…

Classical Analysis and ODEs · Mathematics 2014-04-28 Inom Mirzaev , David Matthew Bortz

All current formulations of nonequilibrium thermodynamics of open chemical reaction networks rely on the assumption of non-interacting species. We develop a general theory which accounts for interactions between chemical species within a…

Statistical Mechanics · Physics 2021-03-09 Francesco Avanzini , Emanuele Penocchio , Gianmaria Falasco , Massimiliano Esposito

Chemical reaction networks in living cells maintain precise control over thousands of metabolites despite operating far from equilibrium under constant perturbations. While mass action kinetics accurately describe the underlying dynamics,…

Optimization and Control · Mathematics 2025-08-27 Steven Diamond

Equilibrium is a rather ideal situation, the exception rather than the rule in Nature. Whenever the external or internal parameters of a physical system are varied its subsequent relaxation to equilibrium may be either impossible or take…

Statistical Mechanics · Physics 2016-10-04 Leticia F. Cugliandolo

The behavior of dynamical system interacting with non-equilibrium medium is investigated. Formally exact kinetic equations are derived for the statistical operator of the dynamical system and the macroscopic parameters of the medium. In the…

Statistical Mechanics · Physics 2016-12-30 Mikheil Zviadadze , Alexander kvirikadze

The process of genetic recombination can be seen as a chemical reaction network with mass-action kinetics. We review the known results on existence, uniqueness, and global stability of an equilibrium in every compatibility class and for all…

Molecular Networks · Quantitative Biology 2015-03-05 Stefan Müller , Josef Hofbauer

A class of chemical reaction networks is described with the property that each positive equilibrium is locally asymptotically stable relative to its stoichiometry class, an invariant subspace on which it lies. The reaction systems treated…

Dynamical Systems · Mathematics 2013-04-11 Pete Donnell , Murad Banaji

A crisp survey is given of chemical reaction networks from the perspective of general nonlinear network dynamics, in particular of consensus dynamics. It is shown how by starting from the complex-balanced assumption the reaction dynamics…

Dynamical Systems · Mathematics 2015-02-10 Arjan van der Schaft , Shodhan Rao , Bayu Jayawardhana

The paper presents amended basic map of states of chemical systems in discrete thermodynamics of chemical equilibria. Uniting two previously found basic map types in one and covering a wider range of situations, it allows us to obtain more…

Chemical Physics · Physics 2011-02-17 B. Zilbergleyt

The quantitative convergence to equilibrium for reaction-diffusion systems arising from complex balanced chemical reaction networks with mass action kinetics is studied by using the so-called entropy method. In the first part of the paper,…

Analysis of PDEs · Mathematics 2016-11-11 Laurent Desvillettes , Klemens Fellner , Bao Quoc Tang
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