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Tree rearrangements such as Nearest Neighbor Interchange (NNI) and Subtree Prune and Regraft (SPR) are commonly used to explore phylogenetic treespace. Computing distances based on them, however, is often intractable, so the efficiently…

Populations and Evolution · Quantitative Biology 2025-12-29 Lena Collienne , Frederick A Matsen

Phylogenetic networks are rooted directed acyclic graphs that represent evolutionary relationships between species whose past includes reticulation events such as hybridisation and horizontal gene transfer. To search the space of…

Combinatorics · Mathematics 2019-04-09 Jonathan Klawitter , Simone Linz

Statistical phylogenetic inference methods use tree rearrangement operations to perform either hill-climbing local search or Markov chain Monte Carlo across tree topologies. The canonical class of such moves are the subtree-prune-regraft…

Discrete Mathematics · Computer Science 2015-11-05 Chris Whidden , Frederick A. Matsen

The subtree prune-and-regraft (SPR) distance metric is a fundamental way of comparing evolutionary trees. It has wide-ranging applications, such as to study lateral genetic transfer, viral recombination, and Markov chain Monte Carlo…

Data Structures and Algorithms · Computer Science 2017-11-07 Chris Whidden , Frederick A. Matsen

A rearrangement operation makes a small graph-theoretical change to a phylogenetic network to transform it into another one. For unrooted phylogenetic trees and networks, popular rearrangement operations are tree bisection and reconnection…

Combinatorics · Mathematics 2023-06-22 Jonathan Klawitter

We present an algorithm that, with high probability, generates a random spanning tree from an edge-weighted undirected graph in $\tilde{O}(n^{4/3}m^{1/2}+n^{2})$ time (The $\tilde{O}(\cdot)$ notation hides $\operatorname{polylog}(n)$…

Data Structures and Algorithms · Computer Science 2017-06-22 David Durfee , Rasmus Kyng , John Peebles , Anup B. Rao , Sushant Sachdeva

We show an $\widetilde{O}(m^{1.5} \epsilon^{-1})$ time algorithm that on a graph with $m$ edges and $n$ vertices outputs its spanning tree count up to a multiplicative $(1+\epsilon)$ factor with high probability, improving on the previous…

Data Structures and Algorithms · Computer Science 2025-05-21 Yang P. Liu , Richard Peng , Junzhao Yang

Phylogenetic trees are leaf-labelled trees, where the leaves correspond to extant species (taxa), and the internal vertices represent ancestral species. The evolutionary history of a set of species can be explained by more than one…

Data Structures and Algorithms · Computer Science 2016-09-07 Asish Mukhopadhyay , Puspal Bhabak

We present the first sub-quadratic time algorithm that with high probability correctly reconstructs phylogenetic trees for short sequences generated by a Markov model of evolution. Due to rapid expansion in sequence databases, such very…

Populations and Evolution · Quantitative Biology 2012-06-01 Daniel G. Brown , Jakub Truszkowski

The nni-distance is a well-known distance measure for phylogenetic trees. We construct an efficient parallel approximation algorithm for the nni-distance in the CRCW-PRAM model running in O(log n) time on O(n) processors. Given two…

Data Structures and Algorithms · Computer Science 2012-05-16 Mikael Gast , Mathias Hauptmann

We give an algorithm for finding the arboricity of a weighted, undirected graph, defined as the minimum number of spanning forests that cover all edges of the graph, in $\sqrt{n} m^{1+o(1)}$ time. This improves on the previous best bound of…

Data Structures and Algorithms · Computer Science 2025-07-22 Ruoxu Cen , Henry Fleischmann , George Z. Li , Jason Li , Debmalya Panigrahi

Network rearrangement operations like SNPR (SubNet Prune and Regraft), a recent generalisation of rSPR (rooted Subtree Prune and Regraft), induce a metric on phylogenetic networks. To search the space of these networks one important…

Combinatorics · Mathematics 2018-10-17 Jonathan Klawitter

We significantly improve known time bounds for solving the minimum cut problem on undirected graphs. We use a ``semi-duality'' between minimum cuts and maximum spanning tree packings combined with our previously developed random sampling…

Data Structures and Algorithms · Computer Science 2007-05-23 David R. Karger

This paper introduces constNJ, the first algorithm for phylogenetic reconstruction of sets of trees with constrained pairwise rooted subtree-prune regraft (rSPR) distance. We are motivated by the problem of constructing sets of trees which…

Populations and Evolution · Quantitative Biology 2009-09-30 Frederick A. Matsen

The subtree prune-and-regraft (SPR) distance metric is a fundamental way of comparing evolutionary trees. It has wide-ranging applications, such as to study lateral genetic transfer, viral recombination, and Markov chain Monte Carlo…

Discrete Mathematics · Computer Science 2016-11-09 Chris Whidden , Frederick A. Matsen

The minimal number of rooted subtree prune and regraft (rSPR) operations needed to transform one phylogenetic tree into another one induces a metric on phylogenetic trees - the rSPR-distance. The rSPR-distance between two phylogenetic trees…

Combinatorics · Mathematics 2023-06-22 Jonathan Klawitter

For an $m$-edge connected simple graph $G$, finding a spanning tree of $G$ with the maximum number of leaves is MAXSNP-complete. The problem remains NP-complete even if $G$ is planar and the maximal degree of $G$ is at most four. Lu and…

Data Structures and Algorithms · Computer Science 2024-04-02 I-Cheng Liao , Hsueh-I Lu

Most of major algorithms for phylogenetic tree reconstruction assume that sequences in the analyzed set either do not have any offspring, or that parent sequences can maximally mutate into just two descendants. The graph resulting from such…

Populations and Evolution · Quantitative Biology 2013-10-09 Piotr Plonski , Jan P. Radomski

The maximum/minimum bisection problems are, given an edge-weighted graph, to find a bipartition of the vertex set into two sets whose sizes differ by at most one, such that the total weight of edges between the two sets is…

Data Structures and Algorithms · Computer Science 2020-09-17 Tesshu Hanaka , Yasuaki Kobayashi , Taiga Sone

We present a new algorithm for generating a uniformly random spanning tree in an undirected graph. Our algorithm samples such a tree in expected $\tilde{O}(m^{4/3})$ time. This improves over the best previously known bound of…

Data Structures and Algorithms · Computer Science 2017-03-16 Aleksander Madry , Damian Straszak , Jakub Tarnawski
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