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In this paper we will address the problem of developing mathematical models for the numerical simulation of the human circulatory system. In particular, we will focus our attention on the problem of haemodynamics in large human arteries.

Dynamical Systems · Mathematics 2007-05-23 Alfio Quarteroni

Probabilistic integration provides a criterion for stopping a simulation when a specified error tolerance is satisfied with high confidence. We comment on some of the modeling assumptions and implementation issues involved in designing an…

Numerical Analysis · Mathematics 2018-12-06 Fred J. Hickernell , R. Jagadeeswaran

Heart murmurs are a common manifestation of cardiovascular diseases and can provide crucial clues to early cardiac abnormalities. While most current research methods primarily focus on the accuracy of models, they often overlook other…

Sound · Computer Science 2024-05-08 Zixing Zhang , Tao Pang , Jing Han , Björn W. Schuller

In experimental causal inference, we distinguish between two sources of uncertainty: design uncertainty, due to the treatment assignment mechanism, and sampling uncertainty, when the sample is drawn from a super-population. This distinction…

Machine learning models are often evaluated using point estimates of performance metrics such as accuracy, F1 score, or mean squared error. Such summaries fail to capture the inherent variability induced by stochastic elements of the…

Machine Learning · Computer Science 2026-05-13 Christoph Lehmann , Yahor Paromau

We study the statistical complexity of estimating partition functions given sample access to a proposal distribution and an unnormalized density ratio for a target distribution. While partition function estimation is a classical problem,…

Machine Learning · Statistics 2026-03-02 Adam Block , Abhishek Shetty

Quantifying errors and losses due to the use of Floating-Point (FP) calculations in industrial scientific computing codes is an important part of the Verification, Validation and Uncertainty Quantification (VVUQ) process. Stochastic…

Three-dimensional cardiovascular fluid dynamics simulations typically require computation of several cardiac cycles before they reach a periodic solution, rendering them computationally expensive. Furthermore, there is currently no…

Computational Engineering, Finance, and Science · Computer Science 2021-06-28 Martin R. Pfaller , Jonathan Pham , Nathan M. Wilson , David W. Parker , Alison L. Marsden

The paper considers the problem of implementation on graphics processors of numerical integration routines for higher order finite element approximations. The design of suitable GPU kernels is investigated in the context of general purpose…

Mathematical Software · Computer Science 2014-03-03 Krzysztof Banaś , Przemysław Płaszewski , Paweł Macioł

This work proposes a novel approach to evaluate and analyze the behavior of multi-population parallel genetic algorithms (PGAs) when running on a cluster of multi-core processors. In particular, we deeply study their numerical and…

Neural and Evolutionary Computing · Computer Science 2025-08-05 Tomohiro Harada , Enrique Alba , Gabriel Luque

The vast majority of stochastic simulation models are imperfect in that they fail to exactly emulate real system dynamics. The inexactness of the simulation model, or model discrepancy, can impact the predictive accuracy and usefulness of…

Methodology · Statistics 2017-07-21 Matthew Plumlee , Henry Lam

Uncertainty in surgery durations continues to be difficult to account for in operating room scheduling. In particular, it remains complex to accurately incorporate uncertainty in surgical overtime constraints within mixed-integer linear…

Optimization and Control · Mathematics 2026-04-29 Cindy Pistorius , J. Theresia van Essen

Computer simulation models are widely used to study complex physical systems. A related fundamental topic is the inverse problem, also called calibration, which aims at learning about the values of parameters in the model based on…

Methodology · Statistics 2024-01-03 Yang Li , Shifeng Xiong

A functional risk curve gives the probability of an undesirable event as a function of the value of a critical parameter of a considered physical system. In several applicative situations, this curve is built using phenomenological…

Statistics Theory · Mathematics 2017-07-26 Bertrand Iooss , Loïc Le Gratiet

Mathematical modeling of cardiac function can provide augmented simulation-based diagnosis tool for complementing and extending human understanding of cardiac diseases which represent the most common cause of worldwide death. As the…

Computational Engineering, Finance, and Science · Computer Science 2021-05-05 Chi Zhang , Jianhang Wang , Massoud Rezavand , Dong Wu , Xiangyu Hu

Bayesian inference and the use of posterior or posterior predictive probabilities for decision making have become increasingly popular in clinical trials. The current practice in Bayesian clinical trials relies on a hybrid…

Methodology · Statistics 2024-04-30 Shirin Golchi , James Willard

We study the problem of data integration from sources that contain probabilistic uncertain information. Data is modeled by possible-worlds with probability distribution, compactly represented in the probabilistic relation model. Integration…

Databases · Computer Science 2016-07-20 Fereidoon Sadri , Gayatri Tallur

Numerical simulation codes are very common tools to study complex phenomena, but they are often time-consuming and considered as black boxes. For some statistical studies (e.g. asset management, sensitivity analysis) or optimization…

Statistics Theory · Mathematics 2017-08-14 Vincent Moutoussamy , Simon Nanty , Benoît Pauwels

Nowadays, high performance computing is becoming more and more important in different fields research and industry, such as medical imaging and diagnostics, mathematics as well as oil exploration. It refers to intensive computing in some…

Distributed, Parallel, and Cluster Computing · Computer Science 2019-02-07 Mouadh Ayachi

A fundamental challenge in probabilistic modeling is to balance expressivity and inference efficiency. Tractable probabilistic models (TPMs) aim to directly address this tradeoff by imposing constraints that guarantee efficient inference of…

Artificial Intelligence · Computer Science 2025-10-28 John Leland , YooJung Choi
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