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We present GridFF, an efficient method for simulating molecules on rigid substrates, derived from techniques used in protein-ligand docking in biochemistry. By projecting molecule-substrate interactions onto precomputed spatial grids with…

Chemical Physics · Physics 2025-08-22 Indranil Mal , Milan Kočí , Paolo Nicolini , Prokop Hapala

Identifying local structural motifs and packing patterns of molecular solids is a challenging task for both simulation and experiment. We demonstrate two novel approaches to characterize local environments in different polymorphs of…

Materials Science · Physics 2024-04-02 Daisuke Kuroshima , Michael Kilgour , Mark E. Tuckerman , Jutta Rogal

The paper proposes a novel adaptive search space decomposition method and a novel gradient-free optimization-based formulation for the pre- and post-buckling analyses of space truss structures. Space trusses are often employed in structural…

Optimization and Control · Mathematics 2022-11-15 Varun Ojha , Bartolomeo Panto , Giuseppe Nicosia

Accurate structural analysis is essential to gain physical knowledge and understanding of atomic-scale processes in materials from atomistic simulations. However, traditional analysis methods often reach their limits when applied to…

We present a global optimization routine for the variational quantum algorithms, which utilizes the dynamic tunneling flow. Originally designed to leverage information gathered by a gradient-based optimizer around local minima, we adapt the…

Quantum Physics · Physics 2024-08-05 Seung Park , Kyunghyun Baek , Seungjin Lee , Mahn-Soo Choi

To facilitate rational molecular and materials design, this research proposes an integrated computational framework that combines stochastic simulation, ab initio quantum chemistry, and molecular docking. The suggested workflow allows…

Materials Science · Physics 2026-01-08 Md Rakibul Karim Akanda , Michael P. Richard

This paper proposes and develops new Newton-type methods to solve structured nonconvex and nonsmooth optimization problems with justifying their fast local and global convergence by means of advanced tools of variational analysis and…

Optimization and Control · Mathematics 2026-03-03 Pham Duy Khanh , Boris S. Mordukhovich , Vo Thanh Phat

Geometry optimization is an important task in quantum chemical calculations to analyze the characteristics of molecules. A top concern on it is a long execution time because time-consuming energy and gradient calculations are repeated…

Chemical Physics · Physics 2024-04-22 Satoshi Imamura , Akihiko Kasagi , Eiji Yoshida

Despite recent advances in automated machine learning, model selection is still a complex and computationally intensive process. For Gaussian processes (GPs), selecting the kernel is a crucial task, often done manually by the expert.…

Machine Learning · Computer Science 2022-10-24 Matthias Bitzer , Mona Meister , Christoph Zimmer

We present a method for electronic structure calculations that retains all of the advantages of real space and addresses the inherent inefficiency of a regular grid, which has equal precision everywhere. The computations are carried out on…

Condensed Matter · Physics 2009-10-28 Gil Zumbach , N. A. Modine , Efthimios Kaxiras

Although spatial indexes shorten the query response time, they rely on complex tree structures to narrow down the search space. Such structures in turn yield additional storage overhead and take a toll on index maintenance. Recently, there…

Databases · Computer Science 2023-09-15 Congying Wang , Jia Yu , Zhuoyue Zhao

An efficient gradient-based method to solve the volume constrained topology optimization problems is presented. Each iterate of this algorithm is obtained by the projection of a Barzilai-Borwein step onto the feasible set consisting of box…

Optimization and Control · Mathematics 2010-06-04 Ruhollah Tavakoli , Hongchao Zhang

Molecular dynamics (MD) has long been the de facto choice for simulating complex atomistic systems from first principles. Recently deep learning models become a popular way to accelerate MD. Notwithstanding, existing models depend on…

Computational Engineering, Finance, and Science · Computer Science 2023-01-10 Fang Wu , Stan Z. Li

Due to the increasing demand for high performance and cost reduction within the framework of complex system design, numerical optimization of computationally costly problems is an increasingly popular topic in most engineering fields. In…

Optimization and Control · Mathematics 2018-06-12 Julien Pelamatti , Loïc Brevault , Mathieu Balesdent , El-Ghazali Talbi , Yannick Guerin

Identifying the atomic structure of organic-inorganic interfaces is challenging with our current research tools. Interpreting the structure of complex molecular adsorbates from microscopy images can be difficult, and using atomistic…

Materials Science · Physics 2020-12-02 Jari Järvi , Patrick Rinke , Milica Todorović

Preliminary spacecraft trajectory optimization is a parameter dependent global search problem that aims to provide a set of solutions that are of high quality and diverse. In the case of numerical solution, it is dependent on the original…

Optimization and Control · Mathematics 2024-12-31 Ryne Beeson , Anjian Li , Amlan Sinha

Table structure recognition is a challenging task due to the various structures and complicated cell spanning relations. Previous methods handled the problem starting from elements in different granularities (rows/columns, text regions),…

Computer Vision and Pattern Recognition · Computer Science 2022-04-21 Liang Qiao , Zaisheng Li , Zhanzhan Cheng , Peng Zhang , Shiliang Pu , Yi Niu , Wenqi Ren , Wenming Tan , Fei Wu

Some methods based on simple regularizing geometric element transformations have heuristically been shown to give runtime efficient and quality effective smoothing algorithms for meshes. We describe the mathematical framework and a…

Computational Geometry · Computer Science 2013-07-09 Dimitris Vartziotis , Benjamin Himpel

Recent learning-based visual localization methods use global descriptors to disambiguate visually similar places, but existing approaches often derive these descriptors from geometric cues alone (e.g., covisibility graphs), limiting their…

Computer Vision and Pattern Recognition · Computer Science 2026-01-09 Son Tung Nguyen , Alejandro Fontan , Michael Milford , Tobias Fischer

We present a novel approach for studying the global dynamics of a vibro-impact pair, that is, a ball moving in a harmonically forced capsule. Motivated by a specific context of vibro-impact energy harvesting, we develop the method with…

Dynamical Systems · Mathematics 2024-12-06 Lanjing Bao , Rachel Kuske , Daniil Yurchenko , Igor Belykh