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Differential privacy is a strong notion for privacy that can be used to prove formal guarantees, in terms of a privacy budget, $\epsilon$, about how much information is leaked by a mechanism. However, implementations of privacy-preserving…

Machine Learning · Computer Science 2019-08-14 Bargav Jayaraman , David Evans

Many biomedical experiments are carried out by pooling individual biological samples. However, pooling samples can potentially hide biological variance and give false confidence concerning the data significance. In the context of microarray…

Quantitative Methods · Quantitative Biology 2008-06-02 Shu-Dong Zhang , Timothy W. Gant

Allowing organizations to share their data for training of machine learning (ML) models without unintended information leakage is an open problem in practice. A promising technique for this still-open problem is to train models on the…

Combining observational and experimental data for causal inference can improve treatment effect estimation. However, many observational data sets cannot be released due to data privacy considerations, so one researcher may not have access…

Methodology · Statistics 2024-08-26 Charlotte Z. Mann , Adam C. Sales , Johann A. Gagnon-Bartsch

Confidence intervals are a fundamental tool for quantifying the uncertainty of parameters of interest. With the increase of data privacy awareness, developing a private version of confidence intervals has gained growing attention from both…

Methodology · Statistics 2024-04-12 Shurong Lin , Mark Bun , Marco Gaboardi , Eric D. Kolaczyk , Adam Smith

Privacy data protection in the medical field poses challenges to data sharing, limiting the ability to integrate data across hospitals for training high-precision auxiliary diagnostic models. Traditional centralized training methods are…

Computer Vision and Pattern Recognition · Computer Science 2024-08-26 Tian Bowen , Xu Zhengyang , Yin Zhihao , Wang Jingying , Yue Yutao

Recently introduced privacy legislation has aimed to restrict and control the amount of personal data published by companies and shared to third parties. Much of this real data is not only sensitive requiring anonymization, but also…

Databases · Computer Science 2020-07-20 Mostafa Milani , Yu Huang , Fei Chiang

The projected increase of genotyping in the clinic and the rise of large genomic databases has led to the possibility of using patient medical data to perform genomewide association studies (GWAS) on a larger scale and at a lower cost than…

Quantitative Methods · Quantitative Biology 2016-04-18 Sean Simmons , Cenk Sahinalp , Bonnie Berger

We study the problem of data release with privacy, where data is made available with privacy guarantees while keeping the usability of the data as high as possible --- this is important in health-care and other domains with sensitive data.…

Machine Learning · Computer Science 2019-01-09 Anh T. Pham , Shalini Ghosh , Vinod Yegneswaran

Privacy protection and uncertainty quantification are increasingly important in data-driven decision making. Conformal prediction provides finite-sample marginal coverage, but existing private approaches often rely on data splitting,…

Machine Learning · Statistics 2026-03-10 Young Hyun Cho , Jordan Awan

Estimating individualized treatment rules - particularly in the context of right-censored outcomes - is challenging because the treatment effect heterogeneity of interest is often small, thus difficult to detect. While this motivates the…

Applications · Statistics 2022-02-16 Erica EM Moodie , Janie Coulombe , Coraline Danieli , Christel Renoux , Susan M Shortreed

This paper presents a stochastic sampling framework for privacy-aware data sharing, where a sensor observes a process correlated with private information. A sampler determines whether to retain or discard sensor observations, balancing the…

Systems and Control · Electrical Eng. & Systems 2025-05-22 Chuanghong Weng , Ehsan Nekouei

Differential Privacy (DP) is the current gold-standard for ensuring privacy for statistical queries. Estimation problems under DP constraints appearing in the literature have largely focused on providing equal privacy to all users. We…

Machine Learning · Computer Science 2025-04-22 Syomantak Chaudhuri , Thomas A. Courtade

In survival analysis, regression models are used to understand the effects of explanatory variables (e.g., age, sex, weight, etc.) to the survival probability. However, for sensitive survival data such as medical data, there are serious…

Machine Learning · Computer Science 2017-08-28 Thông T. Nguyên , Siu Cheung Hui

Preserving the privacy of individuals by protecting their sensitive attributes is an important consideration during microdata release. However, it is equally important to preserve the quality or utility of the data for at least some…

Machine Learning · Statistics 2017-11-07 Dennis Wei , Karthikeyan Natesan Ramamurthy , Kush R. Varshney

Data sharing enables critical advances in many research areas and business applications, but it may lead to inadvertent disclosure of sensitive summary statistics (e.g., means or quantiles). Existing literature only focuses on protecting a…

Cryptography and Security · Computer Science 2024-06-14 Shuaiqi Wang , Rongzhe Wei , Mohsen Ghassemi , Eleonora Kreacic , Vamsi K. Potluru

Large organizations that collect data about populations (like the US Census Bureau) release summary statistics that are used by multiple stakeholders for resource allocation and policy making problems. These organizations are also legally…

Databases · Computer Science 2021-11-08 David Pujol , Yikai Wu , Brandon Fain , Ashwin Machanavajjhala

Adaptive experiment is widely adopted to estimate conditional average treatment effect (CATE) in clinical trials and many other scenarios. While the primary goal in experiment is to maximize estimation accuracy, due to the imperative of…

Methodology · Statistics 2024-02-06 Jiachun Li , Kaining Shi , David Simchi-Levi

This paper focuses on the privacy paradigm of providing access to researchers to remotely carry out analyses on sensitive data stored behind firewalls. We address the situation where the analysis demands data from multiple physically…

Methodology · Statistics 2017-10-20 Joshua Snoke , Timothy R. Brick , Aleksandra Slavkovic , Michael D. Hunter

Organizations are collecting vast amounts of data, but they often lack the capabilities needed to fully extract insights. As a result, they increasingly share data with external experts, such as analysts or researchers, to gain value from…

Machine Learning · Computer Science 2025-05-16 Yusi Wei , Hande Y. Benson , Joseph K. Agor , Muge Capan