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In the recent past, electronic health records and distributed data networks emerged as a viable resource for medical and scientific research. As the use of confidential patient information from such sources become more common, maintaining…

Applications · Statistics 2016-03-18 Paramita Saha-Chaudhuri

Precision medicine is a rapidly expanding area of health research wherein patient level information is used to inform treatment decisions. A statistical framework helps to formalize the individualization of treatment decisions that…

Methodology · Statistics 2021-12-23 Coraline Danieli , Erica Moodie

With the recent bloom of data, there is a huge surge in threats against individuals' private information. Various techniques for optimizing privacy-preserving data analysis are at the focus of research in the recent years. In this paper, we…

Cryptography and Security · Computer Science 2022-11-11 Sayan Biswas , Graham Cormode , Carsten Maple

The sharing of patient-level data necessary for covariate-adjusted survival analysis between medical institutions is difficult due to privacy protection restrictions. We propose a privacy-preserving framework that estimates balanced…

Personalized health analytics increasingly rely on population benchmarks to provide contextual insights such as ''How do I compare to others like me?'' However, cohort-based aggregation of health data introduces nontrivial privacy risks,…

Cryptography and Security · Computer Science 2026-01-21 Richik Chakraborty , Lawrence Liu , Syed Hasnain

The discovery of clinical biomarkers requires large patient cohorts and is aided by a pooled data approach across institutions. In many countries, data protection constraints, especially in the clinical environment, forbid the exchange of…

Machine Learning · Statistics 2023-10-03 Daniela Zöller , Harald Binder

Pooled testing offers an efficient solution to the unprecedented testing demands of the COVID-19 pandemic, although with potentially lower sensitivity and increased costs to implementation in some settings. Assessments of this trade-off…

Applications · Statistics 2021-07-13 Saskia Comess , Hannah Wang , Susan Holmes , Claire Donnat

Objective: To enable privacy-preserving learning of high quality generative and discriminative machine learning models from distributed electronic health records. Methods and Results: We describe general and scalable strategy to build…

Cryptography and Security · Computer Science 2018-06-19 Marina Blanton , Ah Reum Kang , Subhadeep Karan , Jaroslaw Zola

Differential privacy is widely adopted to provide provable privacy guarantees in data analysis. We consider the problem of combining public and private data (and, more generally, data with heterogeneous privacy needs) for estimating…

Machine Learning · Computer Science 2021-11-02 Cecilia Ferrando , Jennifer Gillenwater , Alex Kulesza

In many mobile health interventions, treatments should only be delivered in a particular context, for example when a user is currently stressed, walking or sedentary. Even in an optimal context, concerns about user burden can restrict which…

Machine Learning · Computer Science 2018-12-04 Sabina Tomkins , Predrag Klasnja , Susan Murphy

Distributed health data networks that use information from multiple sources have drawn substantial interest in recent years. However, missing data are prevalent in such networks and present significant analytical challenges. The current…

Cryptography and Security · Computer Science 2021-01-01 Yi Deng , Xiaoqian Jiang , Qi Long

Online collaborative medical prediction platforms offer convenience and real-time feedback by leveraging massive electronic health records. However, growing concerns about privacy and low prediction quality can deter patient participation…

Machine Learning · Computer Science 2025-07-16 Shao-Bo Lin , Xiaotong Liu , Yao Wang

Differential privacy is becoming a gold standard for privacy research; it offers a guaranteed bound on loss of privacy due to release of query results, even under worst-case assumptions. The theory of differential privacy is an active…

Sampling schemes are fundamental tools in statistics, survey design, and algorithm design. A fundamental result in differential privacy is that a differentially private mechanism run on a simple random sample of a population provides…

Methodology · Statistics 2023-06-23 Mark Bun , Jörg Drechsler , Marco Gaboardi , Audra McMillan , Jayshree Sarathy

We introduce profile matching, a multivariate matching method for randomized experiments and observational studies that finds the largest possible unweighted samples across multiple treatment groups that are balanced relative to a covariate…

Methodology · Statistics 2022-07-07 Eric R. Cohn , Jose R. Zubizarreta

Data stewards and analysts can promote transparent and trustworthy science and policy-making by facilitating assessments of the sensitivity of published results to alternate analysis choices. For example, researchers may want to assess…

Methodology · Statistics 2023-08-24 Chengxin Yang , Jerome P. Reiter

We consider the privacy amplification properties of a sampling scheme in which a user's data is used in $k$ steps chosen randomly and uniformly from a sequence (or set) of $t$ steps. This sampling scheme has been recently applied in the…

Machine Learning · Computer Science 2026-02-20 Vitaly Feldman , Moshe Shenfeld

Data quality is an important consideration in many engineering applications and projects. Data collection procedures do not always involve careful utilization of the most precise instruments and strictest protocols. As a consequence, data…

Methodology · Statistics 2023-03-02 Krasymyr Tretiak , Scott Ferson

Differential privacy is a leading protection setting, focused by design on individual privacy. Many applications, in medical / pharmaceutical domains or social networks, rather posit privacy at a group level, a setting we call integral…

Machine Learning · Statistics 2019-07-04 Hisham Husain , Zac Cranko , Richard Nock

In statistical disclosure control, the goal of data analysis is twofold: The released information must provide accurate and useful statistics about the underlying population of interest, while minimizing the potential for an individual…

Methodology · Statistics 2016-07-15 Jing Lei , Anne-Sophie Charest , Aleksandra Slavkovic , Adam Smith , Stephen Fienberg
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