Related papers: A rigorous sharp interface limit of a diffuse inte…
Computational modeling of cancer can help unveil dynamics and interactions that are hard to replicate experimentally. Thanks to the advancement in cancer databases and data analysis technologies, these models have become more robust than…
In this paper, we propose an improved phase field model for interface capturing in simulating two-phase incompressible flows. The model incorporates a second-order diffusion term, which utilizes a nonlinear coefficient to assess the degree…
Using a hydrodynamic lattice-gas model, we study interface growth in a binary fluid with various concentrations of surfactant. We find that the interface is smoothed by small concentrations of surfactant, while microemulsion droplets form…
We study a model introduced by Perthame and Vauchelet that describes the growth of a tumor governed by Brinkman's Law, which takes into account friction between the tumor cells. We adopt the viscosity solution approach to establish an…
In this work, the sharp interface limit of the degenerate Cahn-Hilliard equation (in two space dimensions) with a polynomial double well free energy and a quadratic mobility is derived via a matched asymptotic analysis involving…
Diffuse interface descriptions offer many advantages for the modeling of microstructure evolution. However, the numerical representation of moving diffuse interfaces on discrete numerical grids involves spurious grid friction, which limits…
The aim of this paper is to investigate the asymptotic behavior of a biphase tumor fluid flow derived by 2-scale homogenisation techniques in recent works. This biphase fluid flow model accounts for the capillary wall permeability, and the…
This paper deals with the evolution equation of a curve obtained as the sharp interface limit of a non-linear system of two reaction-diffusion PDEs. This system was introduced as a phase-field model of (crawling) motion of eukaryotic cells…
We use a sharp interface model for active cells to study the jamming transition point and behavior near it by varying cell concentration, active velocity and elasticity, including a binary mixture of soft and stiff cells. We determine the…
Diffuse gliomas are highly infiltrative tumors whose early diagnosis and follow-up usually rely on magnetic resonance imaging (MRI). However, the limited sensitivity of this technique makes it impossible to directly assess the extent of the…
Known as one of the hallmarks of cancer [30], cancer cell invasion of human body tissue is a complicated spatio-temporal multiscale process which enables a localised solid tumour to transform into a systemic, metastatic and fatal disease.…
Phase field models for two-phase flow with a surfactant soluble in possibly both fluids are derived from balance equations and an energy inequality so that thermodynamic consistency is guaranteed. Via a formal asymptotic analysis, they are…
Central to the quest for a deeper understanding of the cancer growth and spread process, the naturally multiscale character of cancer invasion demands appropriate multiscale modelling and analysis approach. The cross-talk between the tissue…
The interfacial diffusion associated with finite volume method (FVM) discretizations of multiphase flows creates the need for an interface sharpening mechanism. Such solutions for structured quadrilateral grids are well documented, but…
The spread of metastases is a crucial process in which some questions remain unanswered. In this work, we focus on tumor cells circulating in the bloodstream, the so-called Circulating Tumor Cells (CTCs). Our aim is to characterize their…
We define a new model of interface roughening which has the property that the minimum of interface height is conserved locally during the growth. This model corresponds to the limit $q \to \infty$ of the q-color dimer deposition-evaporation…
Tumor growth has long been a target of investigation within the context of mathematical and computer modelling. The objective of this study is to propose and analyze a two-dimensional probabilistic cellular automata model to describe…
We introduce a diffuse interface model describing the evolution of a mixture of two different viscous incompressible fluids of equal density. The main novelty of the present contribution consists in the fact that the effects of temperature…
We study a diffuse interface model for the flow of two viscous incompressible Newtonian fluids in a bounded domain. The fluids are assumed to be macroscopically immiscible, but a partial mixing in a small interfacial region is assumed in…
In this paper a macroscopic model of tumor cord growth is developed, relying on the mathematical theory of deformable porous media. Tumor is modeled as a saturated mixture of proliferating cells, extracellular fluid and extracellular…