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Biologically-informed neural networks typically leverage pathway annotations to enhance performance in biomedical applications. We hypothesized that the benefits of pathway integration does not arise from its biological relevance, but…

Quantitative Methods · Quantitative Biology 2025-05-08 Isabella Caranzano , Corrado Pancotti , Cesare Rollo , Flavio Sartori , Pietro Liò , Piero Fariselli , Tiziana Sanavia

Doctors use statistics to advance medical knowledge; we use a medical analogy to introduce statistical inference "from scratch" and to highlight an improvement. Your doctor, perhaps implicitly, predicts the effectiveness of a treatment for…

Methodology · Statistics 2015-11-29 Keli Liu , Xiao-Li Meng

Recent advances in artificial intelligence (AI) - particularly generative AI - present new opportunities to accelerate, or even automate, epidemiological research. Unlike disciplines based on physical experimentation, a sizable fraction of…

Computers and Society · Computer Science 2025-07-22 David Bann , Ed Lowther , Liam Wright , Yevgeniya Kovalchuk

Advances in entity-graph based analysis of histopathology images have brought in a new paradigm to describe tissue composition, and learn the tissue structure-to-function relationship. Entity-graphs offer flexible and scalable…

Image and Video Processing · Electrical Eng. & Systems 2021-07-22 Guillaume Jaume , Pushpak Pati , Valentin Anklin , Antonio Foncubierta , Maria Gabrani

Digital pathology has become a standard in the pathology workflow due to its many benefits. These include the level of detail of the whole slide images generated and the potential immediate sharing of cases between hospitals. Recent…

Human-Computer Interaction · Computer Science 2023-07-18 Cristian Camilo Pulgarín-Ospina , Rocío del Amor , Adrián Colomera , Julio Silva-Rodríguez , Valery Naranjo

Purpose of review: Artificial intelligence (AI) has become popular in medical applications, specifically as a clinical support tool for computer-aided diagnosis. These tools are typically employed on medical data (i.e., image, molecular…

Machine Learning · Computer Science 2022-06-08 Ahmad Chaddad , Yousef Katib , Lama Hassan

Histopathology refers to the examination by a pathologist of biopsy samples. Histopathology images are captured by a microscope to locate, examine, and classify many diseases, such as different cancer types. They provide a detailed view of…

Image and Video Processing · Electrical Eng. & Systems 2020-11-12 Naira Elazab , Hassan Soliman , Shaker El-Sappagh , S. M. Riazul Islam , Mohammed Elmogy

When pneumonia is not found on a chest X-ray, should the report describe this negative observation or omit it? We argue that this question cannot be answered from the X-ray alone and requires a pragmatic perspective, which captures the…

Computation and Language · Computer Science 2023-11-30 Dang Nguyen , Chacha Chen , He He , Chenhao Tan

In this paper, we present a diagnosis method of diseases from clinical data. The data are routine test such as urine test, hematology, chemistries etc. Though those tests have been done for people who check in medical institutes, how each…

Computational Engineering, Finance, and Science · Computer Science 2007-05-23 Gene Kim , MyungHo Kim

Grouping patients meaningfully can give insights about the different types of patients, their needs, and the priorities. Finding groups that are meaningful is however very challenging as background knowledge is often required to determine…

Databases · Computer Science 2019-04-04 Seyed Amin Tabatabaei , Xixi Lu , Mark Hoogendoorn , Hajo A. Reijers

The rapid emergence of highly adaptable and reusable artificial intelligence (AI) models is set to revolutionize the medical field, particularly in the diagnosis and management of Parkinson's disease (PD). Currently, there are no effective…

Machine Learning · Computer Science 2025-02-18 Aite Zhao , Yongcan Liu , Xinglin Yu , Xinyue Xing

There are challenges that must be overcome to make recommender systems useful in healthcare settings. The reasons are varied: the lack of publicly available clinical data, the difficulty that users may have in understanding the reasons why…

Clinical systems operate in safety-critical environments and are not intended to function autonomously; however, they are currently designed to replicate clinicians' diagnoses rather than assist them in the diagnostic process. To enable…

Human-Computer Interaction · Computer Science 2025-04-07 Kailas Dayanandan , Brejesh Lall

The visual analysis of retinal data contributes to the understanding of a wide range of eye diseases. For the evaluation of cross-sectional studies, ophthalmologists rely on workflows and toolsets established in their work environment. That…

Human-Computer Interaction · Computer Science 2023-01-06 Martin Röhlig , Lars Nonnemann , Hans-Jörg Schulz , Oliver Stachs , Heidrun Schumann

Objectives: This study aims to systematically review the literature on the computational processing of the language of pain, or pain narratives, whether generated by patients or physicians, identifying current trends and challenges.…

Computation and Language · Computer Science 2024-05-13 Diogo A. P. Nunes , Joana Ferreira-Gomes , Fani Neto , David Martins de Matos

Applying machine learning in the health care domain has shown promising results in recent years. Interpretable outputs from learning algorithms are desirable for decision making by health care personnel. In this work, we explore the…

Machine Learning · Computer Science 2017-11-30 Marcus Klasson , Kun Zhang , Bo C. Bertilson , Cheng Zhang , Hedvig Kjellström

Business intelligence in the banking industry has been studied extensively in the last decade; however, business executives still do not perceive efficiency in the decision-making process since the management and treatment of information…

Human-Computer Interaction · Computer Science 2025-08-12 Alex Escalante Viteri , Javier Gamboa Cruzado , Leonidas Asto Huaman

Radiology reports are an important means of communication between radiologists and other physicians. These reports express a radiologist's interpretation of a medical imaging examination and are critical in establishing a diagnosis and…

Computer Vision and Pattern Recognition · Computer Science 2017-09-14 Hojjat Salehinejad , Shahrokh Valaee , Aren Mnatzakanian , Tim Dowdell , Joseph Barfett , Errol Colak

This paper presents a study of the approaches in the state-of-the-art in the field of pathological speech signal analysis with a special focus on parametrization techniques. It provides a description of 92 speech features where some of them…

The automatic generation of radiology reports has the potential to assist radiologists in the time-consuming task of report writing. Existing methods generate the full report from image-level features, failing to explicitly focus on…

Computer Vision and Pattern Recognition · Computer Science 2023-09-06 Tim Tanida , Philip Müller , Georgios Kaissis , Daniel Rueckert
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