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Although several measurements and analyses support the idea that the brain is energy-optimized, there is one disturbing, contradictory observation: In theory, computation limited by thermal noise can occur as cheaply as ~$2.9\cdot 10^{-21}$…

Neurons and Cognition · Quantitative Biology 2014-11-24 William B. Levy , Toby Berger , Ilya A. Fleidervish

Understanding how network function constrains neural connectivity is a central challenge in neuroscience. An influential approach is to train neural networks with gradient descent on cognitive tasks and characterize the resulting…

Neurons and Cognition · Quantitative Biology 2026-05-26 Ludwig Hruza , Srdjan Ostojic

We define a neural network as a septuple consisting of (1) a state vector, (2) an input projection, (3) an output projection, (4) a weight matrix, (5) a bias vector, (6) an activation map and (7) a loss function. We argue that the loss…

Machine Learning · Computer Science 2021-02-15 Vitaly Vanchurin

The principle of maximum entropy provides a useful method for inferring statistical mechanics models from observations in correlated systems, and is widely used in a variety of fields where accurate data are available. While the assumptions…

Neurons and Cognition · Quantitative Biology 2017-06-02 Ulisse Ferrari , Tomoyuki Obuchi , Thierry Mora

In this paper, we consider contention resolution algorithms that are augmented with predictions about the network. We begin by studying the natural setup in which the algorithm is provided a distribution defined over the possible network…

Distributed, Parallel, and Cluster Computing · Computer Science 2021-05-27 Seth Gilbert , Calvin Newport , Nitin Vaidya , Alex Weaver

Maximum entropy methods provide a principled path connecting measurements of neural activity directly to statistical physics models, and this approach has been successful for populations of $N\sim 100$ neurons. As $N$ increases in new…

Biological Physics · Physics 2023-10-18 Christopher W. Lynn , Qiwei Yu , Rich Pang , William Bialek , Stephanie E. Palmer

The mammalian brain is a metabolically expensive device, and evolutionary pressures have presumably driven it to make productive use of its resources. For sensory areas, this concept has been expressed more formally as an optimality…

Neurons and Cognition · Quantitative Biology 2016-03-02 Deep Ganguli , Eero P. Simoncelli

In this paper, a Neural network is derived from first principles, assuming only that each layer begins with a linear dimension-reducing transformation. The approach appeals to the principle of Maximum Entropy (MaxEnt) to find the posterior…

Machine Learning · Statistics 2020-02-19 Paul M Baggenstoss

We derive asymptotic formulas for the number of integer partitions with given sums of $j$th powers of the parts for $j$ belonging to a finite, non-empty set $J \subset \mathbb N$. The method we use is based on the `principle of maximum…

Combinatorics · Mathematics 2021-01-01 Gweneth McKinley , Marcus Michelen , Will Perkins

Synapses are information efficient in the sense that their natural conductance values convey as many bits per Joule as possible, but efficiency falls rapidly if the conductance is forced to deviate from its natural value (Harris et al,…

Neurons and Cognition · Quantitative Biology 2026-05-19 James V Stone

Maximum entropy models are increasingly being used to describe the collective activity of neural populations with measured mean neural activities and pairwise correlations, but the full space of probability distributions consistent with…

Biological Physics · Physics 2017-08-22 Badr F. Albanna , Christopher Hillar , Jascha Sohl-Dickstein , Michael R. DeWeese

Maximum entropy principle (MEP) offers an effective and unbiased approach to inferring unknown probability distributions when faced with incomplete information, while neural networks provide the flexibility to learn complex distributions…

Machine Learning · Statistics 2024-12-04 Wuyue Yang , Liangrong Peng , Guojie Li , Liu Hong

Recent work emphasizes that the maximum entropy principle provides a bridge between statistical mechanics models for collective behavior in neural networks and experiments on networks of real neurons. Most of this work has focused on…

Neurons and Cognition · Quantitative Biology 2015-06-05 Gasper Tkacik , Olivier Marre , Thierry Mora , Dario Amodei , Michael J. Berry , William Bialek

Data analysis in science, e.g., high-energy particle physics, is often subject to an intractable likelihood if the observables and observations span a high-dimensional input space. Typically the problem is solved by reducing the…

Data Analysis, Statistics and Probability · Physics 2021-01-14 Stefan Wunsch , Simon Jörger , Roger Wolf , Günter Quast

The well known maximum-entropy principle due to Jaynes, which states that given mean parameters, the maximum entropy distribution matching them is in an exponential family, has been very popular in machine learning due to its "Occam's…

Machine Learning · Computer Science 2016-07-13 Yuanzhi Li , Andrej Risteski

We propose a method to derive the stationary size distributions of a system, and the degree distributions of networks, using maximisation of the Gibbs-Shannon entropy. We apply this to a preferential attachment-type algorithm for systems of…

Physics and Society · Physics 2020-03-17 Cornelia Metzig , Caroline Colijn

The network inference problem arises in biological research when one needs to quantitatively choose the best protein-interaction model for explaining a phenotype. The diverse nature of the data and nonlinear dynamics pose significant…

Molecular Networks · Quantitative Biology 2025-12-22 Guy Karlebach

A fundamental question in the conjunction of information theory, biophysics, bioinformatics and thermodynamics relates to the principles and processes that guide the development of natural intelligence in natural environments where…

Neural and Evolutionary Computing · Computer Science 2024-12-31 Serge Dolgikh

Perceptions and actions, thoughts and memories result from coordinated activity in hundreds or even thousands of neurons in the brain. It is an old dream of the physics community to provide a statistical mechanics description for these and…

Disordered Systems and Neural Networks · Physics 2024-09-04 Leenoy Meshulam , William Bialek

The principle of maximum entropy is a broadly applicable technique for computing a distribution with the least amount of information possible constrained to match empirical data, for instance, feature expectations. We seek to generalize…

Information Theory · Computer Science 2022-05-30 Kenneth Bogert
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