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In many areas of science multiple sets of data are collected pertaining to the same system. Examples are food products which are characterized by different sets of variables, bio-processes which are on-line sampled with different…

An applied problem facing all areas of data science is harmonizing data sources. Joining data from multiple origins with unmapped and only partially overlapping features is a prerequisite to developing and testing robust, generalizable…

Quantifying the dependence between high-dimensional random variables is central to statistical learning and inference. Two classical methods are canonical correlation analysis (CCA), which identifies maximally correlated projected versions…

Machine Learning · Computer Science 2023-09-29 Dor Tsur , Ziv Goldfeld , Kristjan Greenewald

The interdependence and high dimensionality of multivariate signals present significant challenges for denoising, as conventional univariate methods often struggle to capture the complex interactions between variables. A successful approach…

Machine Learning · Computer Science 2024-07-29 Jaesung Choi , Pilwon Kim

The Information Bottleneck (IB) principle offers a compelling theoretical framework to understand how neural networks (NNs) learn. However, its practical utility has been constrained by unresolved theoretical ambiguities and significant…

Machine Learning · Computer Science 2026-02-02 Charles Westphal , Stephen Hailes , Mirco Musolesi

This paper is devoted to the mathematical study of some divergences based on the mutual information well-suited to categorical random vectors. These divergences are generalizations of the "entropy distance" and "information distance". Their…

Statistics Theory · Mathematics 2016-08-16 Jean-François Coeurjolly , Rémy Drouilhet , Jean-François Robineau

Background: Alignment of biological sequences such as DNA, RNA or proteins is one of the most widely used tools in computational bioscience. All existing alignment algorithms rely on heuristic scoring schemes based on biological expertise.…

Genomics · Quantitative Biology 2008-10-27 Orion Penner , Peter Grassberger , Maya Paczuski

The maximal information coefficient (MIC), which measures the amount of dependence between two variables, is able to detect both linear and non-linear associations. However, computational cost grows rapidly as a function of the dataset…

Information Theory · Computer Science 2015-08-18 Ali Mousavi , Richard G. Baraniuk

The assumption of conditional independence among observed variables, primarily used in the Variational Autoencoder (VAE) decoder modeling, has limitations when dealing with high-dimensional datasets or complex correlation structures among…

Machine Learning · Computer Science 2023-10-26 Seunghwan An , Jong-June Jeon

Mutual Information (MI) is a powerful statistical measure that quantifies shared information between random variables, particularly valuable in high-dimensional data analysis across fields like genomics, natural language processing, and…

Machine Learning · Computer Science 2024-12-02 Andre O. Falcao

Accurately estimating the informativeness of individual samples in a dataset is an important objective in deep learning, as it can guide sample selection, which can improve model efficiency and accuracy by removing redundant or potentially…

Machine Learning · Computer Science 2025-05-22 Johannes Kaiser , Kristian Schwethelm , Daniel Rueckert , Georgios Kaissis

Complex systems, from the human brain to the global economy, are made of multiple elements that interact in such ways that the behaviour of the `whole' often seems to be more than what is readily explainable in terms of the `sum of the…

Neurons and Cognition · Quantitative Biology 2021-09-28 Pedro A. M. Mediano , Fernando E. Rosas , Andrea I Luppi , Robin L. Carhart-Harris , Daniel Bor , Anil K. Seth , Adam B. Barrett

Describing statistical dependencies is foundational to empirical scientific research. For uncovering intricate and possibly non-linear dependencies between a single target variable and several source variables within a system, a principled…

Information Theory · Computer Science 2024-03-28 David A. Ehrlich , Kyle Schick-Poland , Abdullah Makkeh , Felix Lanfermann , Patricia Wollstadt , Michael Wibral

We propose an approach to rapidly find the upper limit of separability between datasets that is directly applicable to HEP classification problems. The most common HEP classification task is to use $n$ values (variables) for an object…

High Energy Physics - Experiment · Physics 2017-09-01 Nicholas Carrara , Jesse A. Ernst

The Information bottleneck method is an unsupervised non-parametric data organization technique. Given a joint distribution P(A,B), this method constructs a new variable T that extracts partitions, or clusters, over the values of A that are…

Machine Learning · Computer Science 2013-01-14 Nir Friedman , Ori Mosenzon , Noam Slonim , Naftali Tishby

This paper presents evidence for the idea that much of artificial intelligence, human perception and cognition, mainstream computing, and mathematics, may be understood as compression of information via the matching and unification of…

Artificial Intelligence · Computer Science 2015-07-14 J. Gerard Wolff

Due to increased awareness of data protection and corresponding laws many data, especially involving sensitive personal information, are not publicly accessible. Accordingly, many data collecting agencies only release aggregated data, e.g.…

Methodology · Statistics 2022-04-12 Rajbir-Singh Nirwan , Nils Bertschinger

Small sample sizes are common in many disciplines, which necessitates pooling roughly similar datasets across multiple institutions to study weak but relevant associations between images and disease outcomes. Such data often manifest…

Machine Learning · Computer Science 2024-11-19 Sotirios Panagiotis Chytas , Vishnu Suresh Lokhande , Peiran Li , Vikas Singh

Distributed computation in artificial life and complex systems is often described in terms of component operations on information: information storage, transfer and modification. Information modification remains poorly described however,…

Information Theory · Computer Science 2013-10-10 Joseph T. Lizier , Benjamin Flecker , Paul L. Williams

Causality is a central topic in scientific inquiry, yet for complex systems, the identification and analysis of synergistic causation remain a challenging and fundamental problem. In the context of causal relations among multivariate…

Machine Learning · Statistics 2026-05-06 Mingzhe Yang , Shuo Wang , Jiang Zhang