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Thermophoresis moves molecules along temperature gradients, typically from hot to cold. We superpose fluid flow with thermophoretic molecule flow under well defined microfluidic conditions, imaged by fluorescence microscopy. DNA is trapped…

Biological Physics · Physics 2007-05-23 Stefan Duhr , Dieter Braun

With the continued improvement of sequencing technologies, the prospect of genome-based medicine is now at the forefront of scientific research. To realize this potential, however, we need a revolutionary sequencing method for the…

Biological Physics · Physics 2008-01-03 Michael Zwolak , Massimiliano Di Ventra

A novel non-invasive microscopy technique for imaging and sizing of folded DNA molecules with the use of photovoltaic tweezers and phase-sensitive detection is elaborated and realized. This novel method is compared with the state-of-the-art…

Atomic Physics · Physics 2025-02-27 Lusine Tsarukyan , Anahit Badalyan , Rafael Drampyan

Most bacteriophages are known to inject their double-stranded DNA into bacteria upon receptor binding in an essentially spontaneous way. This downhill thermodynamic process from the intact virion toward the empty viral capsid plus released…

Biological Physics · Physics 2010-01-07 Meerim Jeembaeva , B. Jönsson , Martin Castelnovo , Alex Evilevitch

We present a portable multi-channel, multi-sample UV/vis absorption and fluorescence detection device, which has no moving parts, can operate wirelessly and on batteries, interfaces with smart mobile phones or tablets, and has the…

Instrumentation and Detectors · Physics 2012-05-31 Peter J. Lu , Melanie M. Hoehl , James B. Macarthur , Peter A. Sims , Hongshen Ma , Alexander H. Slocum

Charge transport in porous electrodes is foundational for modern energy storage technologies like supercapacitors, fuel cells, and batteries. Supercapacitors in particular rely solely on storing energy in charged pores. Here, we simulate…

Soft Condensed Matter · Physics 2025-12-12 Aaron D. Ratschow , Alexander J. Wagner , Mathijs Janssen , Steffen Hardt

A novel portable fluorometer combining the attributes of a smartphone with an easy fit, simple and compact sample chamber fabricated using 3D printing has been developed for pH measurements of environmental water in the field. The results…

Quantitative Methods · Quantitative Biology 2015-06-11 Md. Arafat Hossain , John Canning , Sandra Ast , Peter J. Rutledge , Teh Li Yen , Abbas Jamalipour

DNA sequencing is revolutionising the field of medicine. DNA sequencers, the machines which perform DNA sequencing, have evolved from the size of a fridge to that of a mobile phone over the last two decades. The cost of sequencing a human…

Genomics · Quantitative Biology 2021-01-14 Hasindu Gamaarachchi

Using a field-portable, smartphone fluorometer to assess water quality based on the pH response of a designer probe, a map of pH of public tap water sites has been obtained. A custom designed Android application digitally processed and…

Instrumentation and Detectors · Physics 2015-10-27 Arafat Hossain , John Canning , Sandra Ast , Peter J. Rutledge , Abbas Jamalipour

We devised a mobile biometric-based authentication system only relying on local processing. Our Android open source solution explores the capability of current smartphones to acquire, process and match fingerprints using only its built-in…

Cryptography and Security · Computer Science 2017-06-13 J. S. Hammudoglu , J. Sparreboom , J. I. Rauhamaa , J. K. Faber , L. C. Guerchi , I. P. Samiotis , S. P. Rao , J. A. Pouwelse

Background: A smartphone is a promising tool for daily cardiovascular measurement and mental stress monitoring. A smartphone camera-based PhotoPlethysmoGraphy (PPG) and a low-cost thermal camera can be used to create cheap, convenient and…

Medical Physics · Physics 2019-01-03 Youngjun Cho , Simon J. Julier , Nadia Bianchi-Berthouze

We present the first proof-of-concept simulations of detectors using biomaterials to detect particle interactions. The essential idea behind a "DNA detector" involves the attachment of a forest of precisely-sequenced single or…

Our growing ability to tailor healthcare to the needs of individuals has the potential to transform clinical treatment. However, the measurement of multiple biomarkers to inform clinical decisions requires rapid, effective, and affordable…

The widespread use of genetic testing in high risk pregnancies has created strong interest in rapid and accurate molecular diagnostics for common chromosomal aneuploidies. We show here that digital polymerase chain reaction (dPCR) can be…

Quantitative Methods · Quantitative Biology 2007-05-23 H. Christina Fan , Stephen R. Quake

The control of solute fluxes through either microscopic phoresis or hydrodynamic advection is a fundamental way to transport molecules, which are ubiquitously present in nature and technology. We study the transport of large solute such as…

Soft Condensed Matter · Physics 2021-09-29 Tatsuya Fukuyama , Sho Nakama , Yusuke T. Maeda

This work builds on the previous introduction [1] of a coupled experimental-computational system devised to fully characterize the thermal behavior of complex 3D submicron electronic devices. The new system replaces the laser-based surface…

Materials Science · Physics 2007-09-13 Peter E. Raad , Pavel L. Komarov , M. Burzo

Potato late blight, caused by the oomycete pathogen Phytophthora infestans, is one of the most devastating diseases affecting potato crops in the history. Although conventional detection methods of plant diseases such as PCR and LAMP are…

Quantitative Methods · Quantitative Biology 2025-06-23 Jiangnan Zhao , Hanbo Xu , Cifu Xu , Wenlong Yin , Laixin Luo , Gang Liu , Yan Wang

In the post-covid19 era, every new wave of the pandemic causes an increased concern among the masses to learn more about their state of well-being. Therefore, it is the need of the hour to come up with ubiquitous, low-cost, non-invasive…

Signal Processing · Electrical Eng. & Systems 2024-12-04 Ahsan Mehmood , Asma Sarauji , M. Mahboob Ur Rahman , Tareq Y. Al-Naffouri

Smartphone-based heart rate (HR) monitoring apps using finger-over-camera photoplethysmography (PPG) face significant challenges in performance evaluation and device compatibility due to device variability and fragmentation. Manual testing…

Computer Vision and Pattern Recognition · Computer Science 2025-07-01 Ming-Zher Poh , Jonathan Wang , Jonathan Hsu , Lawrence Cai , Eric Teasley , James A. Taylor , Jameson K. Rogers , Anupam Pathak , Shwetak Patel

DNA nanotechnology promises to provide controllable self-assembly on the nanoscale, allowing for the design of static structures, dynamic machines and computational architectures. In this article I review the state-of-the art of DNA…

Soft Condensed Matter · Physics 2015-07-13 Thomas E. Ouldridge