Related papers: Image-Based Modeling of Blood Flow and Oxygen Tran…
We propose an analytical approach to solving the diffusion-convection equations governing oxygen transport in the human placenta. We show that only two geometrical characteristics of a placental cross-section, villi density and the…
The primary exchange units in the human placenta are terminal villi, in which fetal capillary networks are surrounded by a thin layer of villous tissue, separating fetal from maternal blood. To understand how the complex spatial structure…
We present a stream-tube model of oxygen exchange inside a human placenta functional unit (a placentone). The effect of villi density on oxygen transfer efficiency is assessed by numerically solving the diffusion-convection equation in a…
Fetal oxygen delivery and consumption and blood gases in relation to gestational age. Oxygen crosses the placenta by diffusion and placental permeability to O$_2$ is high. Thus, the fetus receives adequate amounts, but vascular Po$_2$ is…
Microcirculation of blood and oxygen transport play important roles in biological function of optic nerve and are directly affected by damages or pathologies. This work develops a multi-domain model for optic nerve, that includes important…
External pressure significantly influences microcirculatory capillary blood flow, yet current studies lack quantitative modeling. This work proposes a nonlinear segmented coupling model between external pressure and capillary flow,…
Diffuse optics has the potential to offer a substantial advancement in fetal health monitoring via enabling continuous measurement of fetal blood oxygen saturation (fSpO$_2$). Aiming to enhance the sensing accuracy and to elucidate the…
The relationship between the spatiotemporal distribution of oxygen transport and blood flow dynamics, accounting for the motion and deformation of individual red blood cells (RBCs), is of fundamental importance for understanding…
Maintaining cerebral blood flow is critical for adequate neuronal function. Previous computational models of brain capillary networks have predicted that heterogeneous cerebral capillary flow patterns result in lower brain tissue partial…
Topological structure of bronchial trees affects transport of gases and aerosols in the respiratory system. We start by providing a quantitative assessment of the ability of the alternative tree representations to predict observable…
Accurate simulations of the flow in the human airway are essential for advancing diagnostic methods. Many existing computational studies rely on simplified geometries or turbulence models, limiting their simulation's ability to resolve flow…
Purpose: To study placental function - both perfusion and an oxygenation surrogate (T2*)-simultaneously and quantitatively in-vivo. Methods: 15 pregnant women were scanned on a 3T MR scanner. For perfusion measurements, a velocity selective…
A detailed study of the transfer of ions in transfer capillaries of electrospray ion sources is presented. The laminar flow field for various capillary sizes and wall temperatures is calculated. It forms the base of ion transfer simulation…
Background and Objective: This proof of concept study investigates mathematical modelling of blood flow and oxygen transport in cerebral microcirculation, focusing on understanding hemodynamic responses. By coupling oxygen transport models…
Airflow through the nasal cavity exhibits a wide variety of fluid dynamicsbehaviour due to the intricacy of the nasal geometry. The flow is naturallyunsteady and perhaps turbulent, despite CFD in the literature that assumesa steady laminar…
Across mammalian species, solute exchange takes place in complex microvascular networks. In the human placenta, the primary exchange units are terminal villi that contain disordered networks of fetal capillaries and are surrounded…
High frequency thickness mode ultrasound is an energy-efficient way to atomize high-viscosity fluid at high flow rate into fine aerosol mists of micron-sized droplet distributions. However the complex physics of the atomization process is…
The rheology of suspensions showing discontinuous shear thickening (DST) is well documented in conventional rheometer with rotating tools, but their study in capillary flow is still lacking. We present results obtained in a homemade…
The paper deals with modeling the liver perfusion intended to improve quantitative analysis of the tissue scans provided by the contrast-enhanced computed tomography (CT). For this purpose, we developed a model of dynamic transport of the…
Background: Experiments have reported low normal tissue toxicities during FLASH radiation, but the mechanism has not been elaborated. Several hypotheses have been proposed to explain the mechanism. The oxygen depletion hypothesis has been…