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Related papers: Modular non-repeating codes for DNA storage

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DNA strings and their properties are widely studied since last 20 years due to its applications in DNA computing. In this area, one designs a set of DNA strings (called DNA code) which satisfies certain thermodynamic and combinatorial…

Information Theory · Computer Science 2025-10-03 Krishna Gopal Benerjee , Manish K Gupta

Modern distributed storage systems apply redundancy coding techniques to stored data. One form of redundancy is based on regenerating codes, which can minimize the repair bandwidth, i.e., the amount of data transferred when repairing a…

Information Theory · Computer Science 2013-01-23 Yuchong Hu , Patrick P. C. Lee , Kenneth W. Shum

Motivated by applications in DNA-based storage, we introduce the new problem of code design in the Damerau metric. The Damerau metric is a generalization of the Levenshtein distance which, in addition to deletions, insertions and…

Information Theory · Computer Science 2018-05-02 Ryan Gabrys , Eitan Yaakobi , Olgica Milenkovic

The nucleotide sequence representation of DNA can be inadequate for resolving protein-DNA binding sites and regulatory substrates, such as those involved in gene expression and horizontal gene transfer. Considering that sequence-like…

Genomics · Quantitative Biology 2020-07-30 Jan Zrimec

We live in a period where bio-informatics is rapidly expanding, a significant quantity of genomic data has been produced as a result of the advancement of high-throughput genome sequencing technology, raising concerns about the costs…

Quantitative Methods · Quantitative Biology 2023-03-10 Mehedi Hasan Sarkar , Adnan Ferdous Ashrafi

In coding for distributed storage systems, efficient data reconstruction and repair through accessing a predefined number of arbitrarily chosen storage nodes is guaranteed by regenerating codes. Traditionally, code parameters, specially the…

Information Theory · Computer Science 2018-01-01 Kaveh Mahdaviani , Soheil Mohajer , Ashish Khisti

The problem of storing large amounts of information safely for a long period of time has become essential. One of the most promising new data storage mediums are the polymer-based data storage systems, like the DNA-storage system. These…

Information Theory · Computer Science 2025-04-21 Ville Junnila , Tero Laihonen , Tuomo Lehtilä

In the current world due to the huge demand for storage, DNA-based storage solution sounds quite promising because of their longevity, low power consumption, and high capacity. However in real life storing data in the form of DNA is quite…

Information Theory · Computer Science 2024-04-09 Sanket Doshi , Mihir Gohel , Manish K. Gupta

With recent high-throughput technology we can synthesize large heterogeneous collections of DNA structures, and also read them all out precisely in a single procedure. Can we use these tools, not only to do things faster, but also to devise…

Data Structures and Algorithms · Computer Science 2021-12-07 Luca Cardelli

Digital information can be encoded in the building-block sequence of macromolecules, such as RNA and single-stranded DNA. Methods of "writing" and "reading" macromolecular strands are currently available, but they are slow and expensive. In…

Emerging Technologies · Computer Science 2017-09-14 Pramod K. Khulbe , Raphael Gruener , Masud Mansuripur

In this paper, we propose a new coded computing technique called "substitute decoding" for general iterative distributed computation tasks. In the first part of the paper, we use PageRank as a simple example to show that substitute decoding…

Information Theory · Computer Science 2018-05-17 Yaoqing Yang , Malhar Chaudhari , Pulkit Grover , Soummya Kar

Learning to solve sequential tasks with recurrent models requires the ability to memorize long sequences and to extract task-relevant features from them. In this paper, we study the memorization subtask from the point of view of the design…

Machine Learning · Computer Science 2020-02-03 Antonio Carta , Alessandro Sperduti , Davide Bacciu

Distributed storage systems support failures of individual devices by the use of replication or erasure correcting codes. While erasure correcting codes offer a better storage efficiency than replication for similar fault tolerance, they…

Distributed, Parallel, and Cluster Computing · Computer Science 2014-12-10 Nicolas Le Scouarnec

In recent years, the emergence of DNA storage systems has led to a widespread focus on the research of codes correcting insertions, deletions, and classic substitutions. During the initial investigation, Levenshtein discovered the VT codes…

Information Theory · Computer Science 2024-01-23 Yuhang Pi , Zhifang Zhang

Erasure coding techniques are getting integrated in networked distributed storage systems as a way to provide fault-tolerance at the cost of less storage overhead than traditional replication. Redundancy is maintained over time through…

Distributed, Parallel, and Cluster Computing · Computer Science 2012-06-12 Lluis Pamies-Juarez , Frédérique Oggier , Anwitaman Datta

High read depth can be used to assemble short sequence repeats. The existing genome assemblers fail in repetitive regions of longer than average read. I propose a new algorithm for a DNA assembly which uses the relative frequency of reads…

Genomics · Quantitative Biology 2015-01-08 Robert M. Nowak

To equip DNA-based data storage with random-access capabilities, Yazdi et al. (2018) prepended DNA strands with specially chosen address sequences called primers and provided certain design criteria for these primers. We provide explicit…

Information Theory · Computer Science 2019-01-07 Yeow Meng Chee , Han Mao Kiah , Hengjia Wei

DNA storage has matured from concept to practical stage, yet its integration with neural compression pipelines remains inefficient. Early DNA encoders applied redundancy-heavy constraint layers atop raw binary data - workable but primitive.…

Machine Learning · Computer Science 2026-02-09 Cihan Ruan , Lebin Zhou , Rongduo Han , Linyi Han , Bingqing Zhao , Chenchen Zhu , Wei Jiang , Wei Wang , Nam Ling

Molecular data systems have the potential to store information at dramatically higher density than existing electronic media. Some of the first experimental demonstrations of this idea have used DNA, but nature also uses a wide diversity of…

Synthetic polymer-based storage seems to be a particularly promising candidate that could help to cope with the ever-increasing demand for archival storage requirements. It involves designing molecules of distinct masses to represent the…

Information Theory · Computer Science 2026-04-02 Anisha Banerjee , Antonia Wachter-Zeh , Eitan Yaakobi