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We consider general high-dimensional spiked sample covariance models and show that their leading sample spiked eigenvalues and their linear spectral statistics are asymptotically independent when the sample size and dimension are…

Statistics Theory · Mathematics 2020-09-25 Zhixiang Zhang , Shurong Zheng , Guangming Pan , Pingshou Zhong

Deep latent generative models have attracted increasing attention due to the capacity of combining the strengths of deep learning and probabilistic models in an elegant way. The data representations learned with the models are often…

Machine Learning · Computer Science 2023-04-04 Zhao Xu , Daniel Onoro Rubio , Giuseppe Serra , Mathias Niepert

We perform a finite sample analysis of the detection levels for sparse principal components of a high-dimensional covariance matrix. Our minimax optimal test is based on a sparse eigenvalue statistic. Alas, computing this test is known to…

Statistics Theory · Mathematics 2014-01-30 Quentin Berthet , Philippe Rigollet

This paper studies the problem of high-dimensional multiple testing and sparse recovery from the perspective of sequential analysis. In this setting, the probability of error is a function of the dimension of the problem. A simple…

Statistics Theory · Mathematics 2011-06-06 Matthew Malloy , Robert Nowak

We develop a stochastic differential equation, called homogenized SGD, for analyzing the dynamics of stochastic gradient descent (SGD) on a high-dimensional random least squares problem with $\ell^2$-regularization. We show that homogenized…

Statistics Theory · Mathematics 2022-05-17 Courtney Paquette , Elliot Paquette , Ben Adlam , Jeffrey Pennington

Modern medicine requires generalised approaches to the synthesis and integration of multimodal data, often at different biological scales, that can be applied to a variety of evidence structures, such as complex disease analyses and…

Quantitative Methods · Quantitative Biology 2019-11-11 Devin Taylor , Simeon Spasov , Pietro Liò

Associating genetic markers with a multidimensional phenotype is an important yet challenging problem. In this work, we establish the equivalence between two popular methods: kernel-machine regression (KMR), and kernel distance covariance…

Machine Learning · Statistics 2014-04-03 Wen-Yu Hua , Debashis Ghosh

In this paper, we consider testing the correlation coefficient matrix between two subsets of high-dimensional variables. We produce a test statistic by using the extended cross-data-matrix (ECDM) methodology and show the unbiasedness of…

Methodology · Statistics 2015-03-24 Kazuyoshi Yata , Makoto Aoshima

Standard statistical learning theory predicts that Large Language Models (LLMs) should overfit because their parameter counts vastly exceed the number of training tokens. Yet, in practice, they generalize robustly. We propose that the…

Machine Learning · Computer Science 2026-02-13 Dibyanayan Bandyopadhyay , Asif Ekbal

Differentially Private Stochastic Gradient Descent (DP-SGD) limits the amount of private information deep learning models can memorize during training. This is achieved by clipping and adding noise to the model's gradients, and thus…

Computer Vision and Pattern Recognition · Computer Science 2023-06-22 Florian A. Hölzl , Daniel Rueckert , Georgios Kaissis

Standard approaches to analysing data in genome-wide association studies (GWAS) ignore any potential functional relationships between genetic markers. In contrast gene pathways analysis uses prior information on functional structure within…

Methodology · Statistics 2013-02-26 M. Silver , P. Chen , L. Ruoying , C. Y. Cheng , T. Y. Wong , E. Tai , Y. Y. Teo , G. Montana

Based on a generalized cosine measure between two symmetric matrices, we propose a general framework for one-sample and two-sample tests of covariance and correlation matrices. We also develop a set of associated permutation algorithms for…

Methodology · Statistics 2018-12-05 Longyang Wu , Chengguo Weng , Xu Wang , Kesheng Wang , Xuefeng Liu

The research presents a machine learning (ML) classifier designed to differentiate between schizophrenia patients and healthy controls by utilising features extracted from electroencephalogram (EEG) data, specifically focusing on…

Machine Learning · Computer Science 2025-03-18 Sara Alkhalifa

Schizophrenia is a serious psychiatric disorder. Its pathogenesis is not completely clear, making it difficult to treat patients precisely. Because of the complicated non-Euclidean network structure of the human brain, learning critical…

Computer Vision and Pattern Recognition · Computer Science 2024-08-28 Yuhong Jiao , Jiaqing Miao , Jinnan Gong , Hui He , Ping Liang , Cheng Luo , Ying Tan

Estimating a sparse covariance matrix is a fundamental problem in high-dimensional statistics. However, thresholding methods developed for independent data are generally not directly applicable to high-dimensional time series, where…

Methodology · Statistics 2026-05-15 Wenhao Zhang , Zhaoxing Gao

Schizophrenia is a globally prevalent psychiatric disorder that severely impairs daily life. Schizophrenia is caused by dopamine imbalances in the fronto-striatal pathways of the brain, which influences fine motor control in the cerebellum.…

Computer Vision and Pattern Recognition · Computer Science 2024-08-14 Rafael Castro , Ishaan Patel , Tarun Patanjali , Priya Iyer

Estimation of the high-dimensional banded covariance matrix is widely used in multivariate statistical analysis. To ensure the validity of estimation, we aim to test the hypothesis that the covariance matrix is banded with a certain…

Methodology · Statistics 2022-04-26 Xiaoyi Wang , Gongjun Xu , Shurong Zheng

Genome-wide association studies (GWAS) provide a means of examining the common genetic variation underlying a range of traits and disorders. In addition, it is hoped that GWAS may provide a means of differentiating affected from unaffected…

Sparse autoencoders (SAEs) are a useful tool for uncovering human-interpretable features in the activations of large language models (LLMs). While some expect SAEs to find the true underlying features used by a model, our research shows…

Machine Learning · Computer Science 2025-01-31 Gonçalo Paulo , Nora Belrose

Schizophrenia (SCZ) is a brain disorder where different people experience different symptoms, such as hallucination, delusion, flat-talk, disorganized thinking, etc. In the long term, this can cause severe effects and diminish life…

Machine Learning · Computer Science 2023-01-19 Shradha Verma , Tripti Goel , M Tanveer , Weiping Ding , Rahul Sharma , R Murugan
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